Opin vísindi

Fletta eftir efnisorði "Multiple myeloma"

Fletta eftir efnisorði "Multiple myeloma"

Röðun: Raða: Niðurstöður:

  • Icon
    Aminopeptidase expression in multiple myeloma associates with disease progression and sensitivity to melflufen 
    Miettinen, Juho J.; Kumari, Romika; Traustadóttir, Gunnhildur Ásta; Huppunen, Maiju Emilia; Sergeev, Philipp; Majumder, Muntasir M.; Schepsky, Alexander; Guðjónsson, Þórarinn; Lievonen, Juha; Bazou, Despina; Dowling, Paul; O‘gorman, Peter; Slipicevic, Ana; Anttila, Pekka; Silvennoinen, Raija; Nupponen, Nina N.; Lehmann, Fredrik; Heckman, Caroline A. (2021-03-26)
    Multiple myeloma (MM) is characterized by extensive immunoglobulin production leading to an excessive load on protein homeostasis in tumor cells. Aminopeptidases contribute to proteolysis by catalyzing the hydrolysis of amino acids from proteins or ...
  • Icon
    Dietary intake is associated with risk of multiple myeloma and its precursor disease 
    Thordardottir, Marianna; Lindqvist, Ebba K.; Lund, Sigrún Helga; Costello, Rene; Burton, Debra; Steingrimsdottir, Laufey; Korde, Neha; Mailankody, Sham; Eiriksdottir, Gudny; Launer, Lenore J.; Gudnason, Vilmundur; Harris, Tamara B.; Landgren, Ola; Torfadottir, Johanna; Kristinsson, Sigurður Yngvi (Public Library of Science (PLoS), 2018-11-01)
    The etiology of monoclonal gammopathy of undetermined significance (MGUS), the precursor state of multiple myeloma (MM), is mostly unknown and no studies have been conducted on the effect of diet on MGUS or progression from MGUS to MM. We aimed to ...
  • Icon
    Mechanisms of transcriptional regulation in Waldenström’s macroglobulinemia and multiple myeloma 
    Anderson, Kimberley (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-04)
    Transcriptional regulatory mechanisms drive the maturation of B cells to plasma cells, with a dramatic transcriptional rewiring taking place during the transition. This rewiring is dependent on a number of factors, including the transcription factor B ...
  • Icon
    Obesity and dietary habits across the lifespan and risk of multiple myeloma and its precursor 
    Þórðardóttir, Maríanna (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-02)
    Background and aim: Multiple myeloma is a malignant chronic B-cell disorder characterized by a monoclonal proliferation of plasma cells in the bone marrow. Almost all multiple myeloma cases are preceded by the premalignant state, monoclonal gammopathy ...