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Fletta eftir efnisorði "Metabolomics/methods"

Fletta eftir efnisorði "Metabolomics/methods"

Röðun: Raða: Niðurstöður:

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    Circulating N-formylmethionine and metabolic shift in critical illness : a multicohort metabolomics study 
    Sigurðsson, Martin Ingi; Kobayashi, Hirotada; Amrein, Karin; Nakahira, Kiichi; Rogers, Angela J.; Pinilla-Vera, Mayra; Baron, Rebecca M.; Fredenburgh, Laura E.; Lasky-Su, Jessica A.; Christopher, Kenneth B. (2022-10-19)
    BACKGROUND: Cell stress promotes degradation of mitochondria which release danger-associated molecular patterns that are catabolized to N-formylmethionine. We hypothesized that in critically ill adults, the response to N-formylmethionine is associated ...
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    Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer 
    Grinde, Maria T; Hilmarsdóttir, Bylgja; Tunset, Hanna Maja; Henriksen, Ida Marie; Kim, Jana; Haugen, Mads H; Rye, Morten Beck; Mælandsmo, Gunhild M; Moestue, Siver A (2019-05-14)
    INTRODUCTION: Glutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione. The drug CB-839 has shown promising effects ...