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Browsing by Subject "Metaanalysis"

Browsing by Subject "Metaanalysis"

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    Hsa-miR-21-3p associates with breast cancer patient survival and targets genes in tumor suppressive pathways 
    Amirfallah, Arsalan; Knutsdottir, Hildur; Arason, Aðalgeir; Hilmarsdóttir, Bylgja; Jóhannsson, Óskar Þór; Agnarsson, Bjarni Agnar; Barkardottir, Rosa B.; Reynisdottir, Inga (2021-11-19)
    Breast cancer is the cancer most often diagnosed in women. MicroRNAs (MIRs) are short RNA molecules that bind mRNA resulting in their downregulation. MIR21 has been shown to be an oncomiR in most cancer types, including breast cancer. Most of the effects ...
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    Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria 
    Day, Felix; Karaderi, Tugce; Jones, Michelle R.; Meun, Cindy; He, Chunyan; Drong, Alex; Kraft, Peter; Lin, Nan; Huang, Hongyan; Broer, Linda; Magi, Reedik; Saxena, Richa; Laisk, Triin; Urbanek, Margrit; Hayes, M. Geoffrey; Thorleifsson, Gudmar; Fernandez-Tajes, Juan; Mahajan, Anubha; Mullin, Benjamin H.; Stuckey, Bronwyn G. A.; Spector, Timothy D.; Wilson, Scott G.; Goodarzi, Mark O.; Davis, Lea; Obermayer-Pietsch, Barbara; Uitterlinden, André G.; Anttila, Verneri; Neale, Benjamin M.; Jarvelin, Marjo-Riitta; Fauser, Bart; Kowalska, Irina; Visser, Jenny A.; Andersen, Marianne; Ong, Ken; Stener-Victorin, Elisabet; Ehrmann, David; Legro, Richard S.; Salumets, Andres; McCarthy, Mark I.; Morin-Papunen, Laure; Thorsteinsdottir, Unnur; Stefansson, Kari; Styrkarsdottir, Unnur; Perry, John R. B.; Dunaif, Andrea; Laven, Joop; Franks, Steve; Lindgren, Cecilia M.; Welt, Corrine K. (Public Library of Science (PLoS), 2018-12-19)
    Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have metabolic disturbances including insulin resistance and dysregulation of glucose ...
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    Occupational issues of adults with ADHD 
    Adamou, Marios; Arif, Muhammad; Asherson, Philip; Aw, Tar-Ching; Bolea, Blanca; Coghill, David; Guðjónsson, Gísli; Halmøy, Anne; Hodgkins, Paul; Müller, Ulrich; Pitts, Mark; Trakoli, Anna; Williams, Nerys; Young, Susan (Biomed Central LTD, 2013-02-17)
    Background: ADHD is a common neurodevelopmental disorder that persists into adulthood. Its symptoms cause impairments in a number of social domains, one of which is employment. We wish to produce a consensus statement on how ADHD affects employment. Methods: ...
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    Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose 
    Wu, Peitao; Rybin, Denis; Bielak, Lawrence F.; Feitosa, Mary F.; Franceschini, Nora; Li, Yize; Lu, Yingchang; Marten, Jonathan; Musani, Solomon K.; Noordam, Raymond; Raghavan, Sridharan; Rose, Lynda M.; Schwander, Karen; Smith, Albert Vernon; Tajuddin, Salman M.; Vojinovic, Dina; Amin, Najaf; Arnett, Donna K.; Bottinger, Erwin P.; Demirkan, Ayse; Florez, Jose C.; Ghanbari, Mohsen; Harris, Tamara B.; Launer, Lenore J.; Liu, Jingmin; Liu, Jun; Mook-Kanamori, Dennis O.; Murray, Alison D.; Nalls, Mike A.; Peyser, Patricia A.; Uitterlinden, André G.; Voortman, Trudy; Bouchard, Claude; Chasman, Daniel; Correa, Adolfo; de Mutsert, Renée; Evans, Michele K.; Gudnason, Vilmundur; Hayward, Caroline; Kao, Linda; Kardia, Sharon L. R.; Kooperberg, Charles; Loos, Ruth J. F.; Province, Michael M.; Rankinen, Tuomo; Redline, Susan; Ridker, Paul M.; Rotter, Jerome I.; Siscovick, David; Smith, Blair H.; van Duijn, Cornelia; Zonderman, Alan B.; Rao, D. C.; Wilson, James G.; Dupuis, Josée; Meigs, James B.; Liu, Ching-Ti; Vassy, Jason L. (Public Library of Science (PLoS), 2020-05-07)
    Smoking is a potentially causal behavioral risk factor for type 2 diabetes (T2D), but not all smokers develop T2D. It is unknown whether genetic factors partially explain this variation. We performed genome-environment-wide interaction studies to ...