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Fletta eftir efnisorði "Mergæxli"

Fletta eftir efnisorði "Mergæxli"

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    Dietary intake is associated with risk of multiple myeloma and its precursor disease 
    Thordardottir, Marianna; Lindqvist, Ebba K.; Lund, Sigrún Helga; Costello, Rene; Burton, Debra; Steingrimsdottir, Laufey; Korde, Neha; Mailankody, Sham; Eiriksdottir, Gudny; Launer, Lenore J.; Gudnason, Vilmundur; Harris, Tamara B.; Landgren, Ola; Torfadottir, Johanna; Kristinsson, Sigurður Yngvi (Public Library of Science (PLoS), 2018-11-01)
    The etiology of monoclonal gammopathy of undetermined significance (MGUS), the precursor state of multiple myeloma (MM), is mostly unknown and no studies have been conducted on the effect of diet on MGUS or progression from MGUS to MM. We aimed to ...
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    Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma 
    Gudbjartsson, Daniel; Thorsteinsdottir, Unnur (Springer Science and Business Media LLC, 2018-09-13)
    Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of the heritability remains unexplained. We report a new GWAS, a meta-analysis with previous GWAS and a replication series, ...
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    Mechanisms of transcriptional regulation in Waldenström’s macroglobulinemia and multiple myeloma 
    Anderson, Kimberley (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-04)
    Transcriptional regulatory mechanisms drive the maturation of B cells to plasma cells, with a dramatic transcriptional rewiring taking place during the transition. This rewiring is dependent on a number of factors, including the transcription factor B ...
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    Monoclonal gammopathy of what significance?: Overcoming the methodological limitations of studying an asymptomatic precursor disorder 
    Rögnvaldsson, Sæmundur (University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-10-10)
    Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic disorder caused by the accumulation of monoclonal immunoglobulin secreting cells in the bone marrow. The main clinical implication of MGUS is that it’s the precursor of multiple ...
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    Obesity and dietary habits across the lifespan and risk of multiple myeloma and its precursor 
    Þórðardóttir, Maríanna (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-02)
    Background and aim: Multiple myeloma is a malignant chronic B-cell disorder characterized by a monoclonal proliferation of plasma cells in the bone marrow. Almost all multiple myeloma cases are preceded by the premalignant state, monoclonal gammopathy ...
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    Outcome and survival of myeloma patients diagnosed 2008–2015. Real-world data on 4904 patients from the Swedish Myeloma Registry 
    Blimark, Cecilie Hveding; Turesson, Ingemar; Genell, Anna; Ahlberg, Lucia; Björkstrand, Bo; Carlson, Kristina; Forsberg, Karin; Juliusson, Gunnar; Linder, Olle; Mellqvist, Ulf-Henrik; Nahi, Hareth; Kristinsson, Sigurður Yngvi (Ferrata Storti Foundation (Haematologica), 2017-12-07)
    Epidemiology and outcome of myeloma are mainly reported from large university centers and collaborative groups, and do not represent ‘real-world’ patients. The Swedish Myeloma Registry is a prospective population-based registry documenting characteristics, ...
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    Second Malignancies in Patients with Multiple Myeloma: Risk Factors and Impact on Survival 
    Jónsdóttir, Guðbjörg (University of Iceland, School of Health Sciences, Faculty of Medicine, 2021-05-21)
    Inngangur: Með tilkomu áhrifaríkari lyfja í meðhöndlun sjúklinga með mergæxli síðastliðna áratugi hefur lifun þeirra stóraukist. Þessi aukna lifun hefur leitt til aukinnar áherslu rannsakennda á langtíma afleiðingum í formi þróun annarra krabbameina. ...