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Fletta eftir efnisorði "MS sjúkdómur"

Fletta eftir efnisorði "MS sjúkdómur"

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    Adverse events related to biologicals used for patients with multiple sclerosis: a comparison between information originating from regulators and information originating from the scientific community 
    Minnema, L. A.; Giezen, T. J.; Egberts, T. C. G.; Leufkens, H. G. M.; Gardarsdottir, Helga (Wiley, 2020-05-10)
    Background and purpose: Clinical decision making is facilitated by healthcare professionals’ and patients’ adequate knowledge of the adverse events. This is especially important for biologicals used for treating multiple sclerosis (MS). So far, little ...
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    Áhrif lyfsins fampridíns á skerta göngugetu sjúklinga með MS (Multiple Sclerosis) 
    Guðjónsdóttir, Björg; Hjaltason, Haukur; Andrésdóttir, Guðbjörg Þóra (2021-04)
    INTRODUCTION: Fampridine is a drug for people with Multiple Sclerosis (MS). It is a broad-spectrum voltage-dependent potassium channel blocker that enhances synaptic transmission. The drug has been shown to be able to enhance conduction in demyelinated ...
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    DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis 
    Kular, Lara; Liu, Yun; Ruhrmann, Sabrina; Zheleznyakova, Galina; Marabita, Francesco; Gomez-Cabrero, David; James, Tojo; Ewing, Ewoud; Lindén, Magdalena; Górnikiewicz, Bartosz; Aeinehband, Shahin; Stridh, Pernilla; Link, Jenny; Andlauer, Till F. M.; Gasperi, Christiane; Wiendl, Heinz; Zipp, Frauke; Gold, Ralf; Tackenberg, Björn; Weber, Frank; Hemmer, Bernhard; Strauch, Konstantin; Heilmann-Heimbach, Stefanie; Rawal, Rajesh; Schminke, Ulf; Schmidt, Carsten O.; Kacprowski, Tim; Franke, Andre; Laudes, Matthias; Dilthey, Alexander T.; Celius, Elisabeth G.; Søndergaard, Helle B.; Tegnér, Jesper; Harbo, Hanne F.; Oturai, Annette B.; Sigurgeir Ólafsson; Eggertsson, Hannes; Halldórsson, Bjarni; Hjaltason, Haukur; Elías Ólafsson; Jonsdottir, Ingileif; Stefansson, Kari; Olsson, Tomas; Piehl, Fredrik; Ekström, Tomas J.; Kockum, Ingrid; Feinberg, Andrew P.; Jagodic, Maja (Springer Science and Business Media LLC, 2018-06-19)
    The human leukocyte antigen (HLA) haplotype DRB1*15:01 is the major risk factor for multiple sclerosis (MS). Here, we find that DRB1*15:01 is hypomethylated and predominantly expressed in monocytes among carriers of DRB1*15:01. A differentially methylated ...
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    Epidemiology of Multiple Sclerosis in Iceland 2002-2007 
    Elíasdóttir, Ólöf Jóna (University of Iceland, School of Health Sciences, Faculty of Medicine, 2020)
    Purpose and aims: Multiple sclerosis (MS) is an autoimmune disease that leads to damage in the central nervous system. Although the cause of MS is still unknown, the generally accepted view is that environmental and life-style factors influence the ...
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    Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations 
    Ólafsson, Sigurgeir; Stridh, Pernilla; Bos, Steffan Daniël; Ingason, Andrés; Euesden, Jack; sulem, patrick; Thorleifsson, Gudmar; Gústafsson, Ómar; Jóhannesson, Ari; Geirsson, Árni J.; Þórsson, Árni V.; Sigurgeirsson, Bárður; Ludviksson, Bjorn; Ólafsson, Elías; Kristjansdottir, Helga; Jónasson, Jón G.; Ólafsson, Jón Hjaltalín; Örvar, Kjartan B.; Benediktsson, Rafn; Bjarnason, Ragnar Grímur; Kristjánsdóttir, Sjöfn; Gislason, Thorarinn; Valdimarsson, Trausti; Mikaelsdóttir, Evgenía; Sigurðsson, Snævar; Jonsson, Stefan; Rafnar, Thorunn; Aarsland, Dag; Djurovic, Srdjan; Fladby, Tormod; Knudsen, Gun Peggy; Celius, Elisabeth G.; Myhr, Kjell-Morten; Gröndal, Gerður; Steinsson, Kristján; Valdimarsson, Helgi; Björnsson, Sigurður; Björnsdóttir, Unnur Steina; Björnsson, Einar Stefán; Nilsson, Bjorn; Andreassen, Ole A.; Alfredsson, Lars; Hillert, Jan; Kockum, Ingrid Skelton; Másson, Gísli; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Stefansson, Hreinn; Hjaltason, Haukur; Harbo, Hanne F.; Olsson, Tomas; Jonsdottir, Ingileif; Stefansson, Kari (Springer Nature, 2017-08-08)
    A meta-analysis of publicly available summary statistics on multiple sclerosis combined with three Nordic multiple sclerosis cohorts (21,079 cases, 371,198 controls) revealed seven sequence variants associating with multiple sclerosis, not reported ...
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    Genetic Variation and Expression of the IRF5 Gene in Autoimmune Diseases 
    Kristjánsdóttir, Guðlaug Þóra (Acta Universitatis Upsaliensis, 2009)
    The interferon regulatory factor 5 (IRF5) gene encodes a transcription factor that plays an important role in the innate as well as in the cell-mediated immune response. The IRF5 gene has received considerable attention since it was shown to be associated ...
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    Problems and Pitfalls of Identifying Remyelination in Multiple Sclerosis 
    Neumann, Bjoern; Foerster, Sarah; Zhao, Chao; Bodini, Benedetta; Reich, Daniel S.; Bergles, Dwight E.; Káradóttir, Ragnhildur Þóra; Lubetzki, Catherine; Lairson, Luke L.; Zalc, Bernard; Stankoff, Bruno; Franklin, Robin J.M. (2020-05-07)
    Regenerative medicines that promote remyelination in multiple sclerosis (MS) are making the transition from laboratory to clinical trials. While animal models provide the experimental flexibility to analyze mechanisms of remyelination, here we discuss ...