Objective Diabetes in pregnancy and consequently the need for treatment with antidiabetic medication (ADM) has become increasingly prevalent. The prevalence and patterns of use of ADM in pregnancy from 2006 onward in seven different countries was ...

Ocular drug delivery is very challenging due to the anatomical and physiological barriers of the eye. Poor aqueous solubility of many drugs and short retention time at ocular surfaces makes the formulation of topical dosage forms even more challenging. ...

A subgroup of patients treated with infliximab lose response to the treatment and one reason for this is the development of anti-drug antibodies (ADA). If used optimally, measuring drug and ADA level could lead to a more personalized and efficient ...

Inherited retinal degeneration (RD), a rare neurodegenerative group of retinal blinding disorders and is characterized by a progressive loss of retinal photoreceptor cells that are responsible for vision. The symptoms of RD include onset of night ...

Melphalan flufenamide (hereinafter referred to as “melflufen”) is a peptide-conjugated drug currently in phase 3 trials for the treatment of relapsed or refractory multiple myeloma. Due to its lipophilic nature, it readily enters cells, where it is ...

Objectives To determine in a retrospective cohort whether patients with psoriatic arthritis (PsA) who would not have fulfilled the inclusion criteria for randomised controlled trials (RCTs) for the TNF inhibitor (TNFi) chosen for their treatment (excl) ...

Töfluslátta hófst í Englandi 1844. Fyrstu töflur innihéldu vatnsleysin sölt samkvæmt forskrift Brockedons og voru sennilega slegnar án hjálparefna. Tímamót urðu um 1887 þegar tekið var að nota mjölva (amylum maydis) í Bandaríkjunum til þess að sundra ...