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Browsing by Subject "Lungnasjúkdómar"

Browsing by Subject "Lungnasjúkdómar"

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  • Yanes, Manar; Santoni, Giola; Maret-Ouda, John; Ness-Jensen, Eivind; Färkkilä, Martti; Lynge, Elsebeth; Nwaru, Bright; Pukkala, Eero; Romundstad, Pål; Tryggvadottir, Laufey; von Euler-Chelpin, My; Lagergren, Jesper (Elsevier BV, 2020-10)
    Introduction: Airway micro-aspiration might contribute to the proposed associations between gastroesophageal reflux disease (GERD) and some lung diseases, including lung cancer. This study aimed to examine the hypothesis that antireflux surgery decreases ...
  • Ingadottir, Arora Ros; Beck, Anne M.; Baldwin, Christine; Weekes, C. Elizabeth; Geirsdottir, Olof; Ramel, Alfons; Gislason, Thorarinn; Gunnarsdottir, Ingibjorg (Cambridge University Press (CUP), 2018-03-06)
    Low energy and protein intakes have been associated with an increased risk of malnutrition in outpatients with chronic obstructive pulmonary disease (COPD). We aimed to assess the energy and protein intakes of hospitalised COPD patients according to ...
  • Hasan, Shakir; Kulkarni, Nikhil Nitin; Asbjarnarson, Arni; Linhartova, Irena; Osicka, Radim; Sebo, Peter; Gudmundsson, Gudmundur H (American Society for Microbiology, 2017-12-04)
    The airway epithelium restricts the penetration of inhaled pathogens into the underlying tissue and plays a crucial role in the innate immune defense against respiratory infections. The whooping cough agent, Bordetella pertussis, adheres to ciliated ...
  • Jensson, Brynjar Örn; Hansdottir, Sif; Arnadottir, Gudny; Sulem, Gerald; Kristjansson, Ragnar; Oddsson, Asmundur; Benonisdottir, Stefania; Jónsson, Hákon; Helgason, Agnar; Sæmundsdóttir, Jóna; Magnússon, Ólafur T.; Másson, Gísli; Thorisson, Gudmundur; Jónasdóttir, Aðalbjörg; Jónasdóttir, Áslaug; Sigurðsson, Ásgeir; Jonsdottir, Ingileif; Pétursdóttir, Vigdís; Kristinsson, Jón R.; Gudbjartsson, Daniel; Thorsteinsdottir, Unnur; Arngrimsson, Reynir; sulem, patrick; Guðmundsson, Gunnar; Stefansson, Kari (Springer Nature, 2017-11-14)
    Background: Rare missense mutations in the gene encoding coatomer subunit alpha (COPA) have recently been shown to cause autoimmune interstitial lung, joint and kidney disease, also known as COPA syndrome, under a dominant mode of inheritance. Case ...
  • Sigurgeirsdottir, Jonina; Halldorsdottir, Sigridur; Arnardóttir, Ragnheiður Harpa; Gudmundsson, Gunnar; Björnsson, Eythor (Dove Medical Press Ltd., 2019-05-16)
    Background: COPD is a common cause of morbidity and mortality. The aim of this study was to explore patients’ experiences, self-reported needs, and needs-driven strategies to cope with self-management of COPD. Patients and methods: In this phenomenological ...
  • Armesto Jimenez, Amaranta (University of Iceland, School of Health Sciences, Faculty of Medicine, 2018-08-17)
    Idiopathic pulmonary fibrosis is a severe lung disease with unknown aetiology. The lifespan is approximately 3 to 5 years after diagnosis, and the treatments available such as lung transplant are high risk and are not suitable for all patients. In ...
  • Myszor, Iwona Teresa (University of Iceland, School of Engineering and Natural Sciences, Faculty of Life and Environmental Sciences, 2021-02)
    Innate immunity of the lung epithelium provides efficient defenses against pathogens or other stress factors by secretion of antimicrobial peptides, presence of cellular junction proteins and autophagy. Upon activation through epithelial cell receptors ...
  • Allen, Richard J.; Guillen-Guio, Beatriz; Oldham, Justin M.; Ma, Shwu-Fan; Dressen, Amy; Paynton, Megan L.; Kraven, Luke M.; Obeidat, Ma'en; Li, Xuan; Ng, Michael; Braybrooke, Rebecca; Molina-Molina, Maria; Hobbs, Brian D.; Putman, Rachel K.; Sakornsakolpat, Phuwanat; Booth, Helen L.; Fahy, William A.; Hart, Simon P.; Hill, Mike R.; Hirani, Nik; Hubbard, Richard B.; McAnulty, Robin J.; Millar, Ann B.; Navaratnam, Vidyia; Oballa, Eunice; Parfrey, Helen; Saini, Gauri; Whyte, Moira K. B.; Zhang, Yingze; Kaminski, Naftali; Adegunsoye, Ayodeji; Strek, Mary E.; Neighbors, Margaret; Sheng, Xuting R.; Guðmundsson, Gunnar; Gudnason, Vilmundur; Hatabu, Hiroto; Lederer, David J.; Manichaikul, Ani; Newell, John D.; O’Connor, George T.; Ortega, Victor E.; Xu, Hanfei; Fingerlin, Tasha E.; Bossé, Yohan; Hao, Ke; Joubert, Philippe; Nickle, David C.; Sin, Don D.; Timens, Wim; Furniss, Dominic; Morris, Andrew P.; Zondervan, Krina T.; Hall, Ian P.; Sayers, Ian; Tobin, Martin D.; Maher, Toby M.; Cho, Michael H.; Hunninghake, Gary M.; Schwartz, David A.; Yaspan, Brian L.; Molyneaux, Philip L.; Flores, Carlos; Noth, Imre; Jenkins, R. Gisli; Wain, Louise V. (American Thoracic Society, 2020-03-01)
    Rationale: Idiopathic pulmonary fibrosis (IPF) is a complex lung disease characterized by scarring of the lung that is believed to result from an atypical response to injury of the epithelium. Genome-wide association studies have reported signals of ...
  • Guinde, Julien; Benoit, Audrey; Frankel, Diane; Robert, Stéphane; Ostacolo, Kevin; Lévy, Nicolas; Astoul, Philippe; Roll, Patrice; Kaspi, Elise (MDPI AG, 2020-02-26)
    In lung adenocarcinoma, low lamin A expression in pleural metastatic cells has been proposed as a pejorative factor. miR-9 physiologically inhibits the expression of lamin A in neural cells and seems to be a central actor in the carcinogenesis and the ...
  • Ingadottir, Arora Ros; Beck, Anne Marie; Baldwin, Christine; Weekes, Christine Elizabeth; Geirsdottir, Olof; Ramel, Alfons; Gislason, Thorarinn; Gunnarsdottir, Ingibjorg (BMJ, 2019-01)
    Introduction Intervention studies have mainly used oral nutritional supplements (ONS) for the management of patients with chronic obstructive pulmonary disease (COPD) identified as at nutritional risk. In this 12-month randomised feasibility trial, we ...
  • Flexeder, Claudia; Zock, Jan-Paul; Jarvis, Deborah; Verlato, Giuseppe; Olivieri, Mario; Benke, Geza; Abramson, Michael J.; Sigsgaard, Torben; Svanes, Cecilie; Torén, Kjell; Nowak, Dennis; Jõgi, Rain; Martinez-Moratalla, Jesús; Demoly, Pascal; Janson, Christer; Gislason, Thorarinn; Bono, Roberto; Holm, Mathias; Franklin, Karl A.; Garcia-Aymerich, Judith; Siroux, Valérie; Leynaert, Bénédicte; Dorado Arenas, Sandra; Corsico, Angelo Guido; Pereira-Vega, Antonio; Probst-Hensch, Nicole; Urrutia Landa, Isabel; Schulz, Holger; Heinrich, Joachim (Springer Science and Business Media LLC, 2019-02-14)
    Background: Early life exposure to tobacco smoke has been extensively studied but the role of second-hand smoke (SHS) for new-onset respiratory symptoms and lung function decline in adulthood has not been widely investigated in longitudinal studies. ...