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Browsing by Subject "Lipoprotein"

Browsing by Subject "Lipoprotein"

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    The impact of APOE genotype on survival: Results of 38,537 participants from six population-based cohorts (E2-CHARGE) 
    Wolters, Frank J.; Yang, Qiong; Biggs, Mary L.; Jakobsdottir, Johanna; Li, Shuo; Evans, Daniel S.; Bis, Joshua C.; Harris, Tamara B.; Vasan, Ramachandran S.; Zilhao, Nuno R.; Ghanbari, Mohsen; Ikram, M. Arfan; Launer, Lenore; Psaty, Bruce M.; Tranah, Gregory J.; Kulminski, Alexander M.; Gudnason, Vilmundur; Seshadri, Sudha (Public Library of Science (PLoS), 2019-07-29)
    Background Apolipoprotein E is a glycoprotein best known as a mediator and regulator of lipid transport and uptake. The APOE-e4 allele has long been associated with increased risks of Alzheimer's disease and mortality, but the effect of the less prevalent ...