Opin vísindi

Browsing by Subject "Lifrarsjúkdómar"

Browsing by Subject "Lifrarsjúkdómar"

Sort by: Order: Results:

  • Grétarsdóttir, Helga M.; Björnsdóttir, Elín; Bjornsson, Einar (S. Karger AG, 2018-06-15)
    We describe a case of acute liver injury and migratory arthralgia in a patient receiving bicalutamide treatment for prostate cancer. A 67-year-old male with metastatic prostate cancer presented with a 6-day history of migratory arthralgia. He had been ...
  • Björnsson, Einar Stefán (2021-06-28)
    Drug-induced liver injury (DILI) should be considered in all patients with recent elevation of liver tests without obvious etiology and normal hepatobiliary imaging. There is currently no biomarker that is helpful in diagnosis which relies on clinical ...
  • Jónasson, Jón Gunnlaugur; Guðnason, Hafsteinn Ó.; Kristinsson, Jón Örvar; Bergmann, Óttar Már; Ólafsson , S.; Björnsson, Einar Stefán (2019-09)
    INNGANGUR Frumkomin trefjunargallgangabólga er langvinnur bólgusjúkdómur í gallvegum innan og/eða utan lifrar sem getur valdið skorpulifur, lokastigs lifrarbilun og leitt til lifrarígræðslu. Bólgusjúkdómar í meltingarvegi, fyrst og fremst sáraristilbólga, ...
  • Nicoletti, Paola; Devarbhavi, Harshad; Goel, Ashish; Venkatesan, Radha; Eapen, Chundamannil E.; Grove, Jane I.; Zafer, Samreen; Björnsson, Einar Stefán; Lucena, M. Isabel; Andrade, Raul J.; Pirmohamed, Munir; Wadelius, Mia; Larrey, Dominique; Maitland-van der Zee, Anke Hilse; Ibanez, Luisa; Watkins, Paul B.; Daly, Ann K.; Aithal, Guruprasad P. (2021-04)
    Drug-induced liver injury (DILI) is a complication of treatment with antituberculosis (TB) drugs, especially in isoniazid (INH)-containing regimens. To investigate genetic risk factors, we performed a genomewide association study (GWAS) involving anti-TB ...
  • Niu, Hao; Sanabria-Cabrera, Judith; Alvarez-Alvarez, Ismael; Robles-Diaz, Mercedes; Stankevičiūtė, Simona; Aithal, Guruprasad P.; Björnsson, Einar Stefán; Andrade, Raul J.; Lucena, M. Isabel (2021-02)
    Conducting randomised clinical trials (RCTs) in idiosyncratic drug-induced liver injury (DILI) is challenging. This systematic review aims to summarise the design and findings of RCTs in the prevention and management of idiosyncratic DILI. A systematic ...
  • Björnsson, Einar Stefán; Vucic, Vesna; Stirnimann, Guido; Robles-Díaz, Mercedes (2022-02-10)
    Introduction: Apart from cessation of the implicated agent leading to drug-induced liver injury (DILI), there is no standard therapy for DILI. Corticosteroids have been used in DILI, although their efficacy is unclear. Published data showed either ...
  • Robles-Díaz, Mercedes; Nezic, Lana; Vujic-Aleksic, Vesna; Björnsson, Einar Stefán (2021-10-27)
    Introduction: Treatment is generally not available for drug-induced liver injury (DILI) patients except in some specific circumstances. The management of DILI is based on the withdrawal of the responsible drug and monitoring the patients and only a few ...
  • Xu, Jason; Bjornsson, Einar; Sundaram, Vinay (Oxford University Press (OUP), 2015-12-14)
    Giant cell arteritis (GCA) is a vasculitis of medium and large sized vessels that occurs most often in people >50 years of age with associated symptoms of fever, weight loss, headache and jaw claudication. Polymyalgia rheumatica (PMR), which is ...