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Browsing by Subject "Immunohistochemistry"

Browsing by Subject "Immunohistochemistry"

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    BRN2 is a non-canonical melanoma tumor-suppressor 
    Hamm, Michael; Sohier, Pierre; Petit, Valérie; Raymond, Jérémy H.; Delmas, Véronique; Le Coz, Madeleine; Gesbert, Franck; Kenny, Colin; Aktary, Zackie; Pouteaux, Marie; Rambow, Florian; Sarasin, Alain; Charoenchon, Nisamanee; Bellacosa, Alfonso; Sanchez-del-Campo, Luis; Mosteo, Laura; Lauss, Martin; Meijer, Dies; Steingrímsson, Eiríkur; Jönsson, Göran B.; Cornell, Robert A.; Davidson, Irwin; Goding, Colin R.; Larue, Lionel (2021-06-17)
    While the major drivers of melanoma initiation, including activation of NRAS/BRAF and loss of PTEN or CDKN2A, have been identified, the role of key transcription factors that impose altered transcriptional states in response to deregulated signaling ...
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    Diagnostic gastrointestinal markers in primary lung cancer and pulmonary metastases 
    Malmros, Karina; Lindholm, Andreas; Vidarsdottir, Halla; Jirström, Karin; Nodin, Björn; Botling, Johan; Mattsson, Johanna S M; Micke, Patrick; Planck, Maria; Jönsson, Mats; Staaf, Johan; Brunnström, Hans (2023-06-22)
    Histopathological diagnosis of pulmonary tumors is essential for treatment decisions. The distinction between primary lung adenocarcinoma and pulmonary metastasis from the gastrointestinal (GI) tract may be difficult. Therefore, we compared the diagnostic ...
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    Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer 
    Grinde, Maria T; Hilmarsdóttir, Bylgja; Tunset, Hanna Maja; Henriksen, Ida Marie; Kim, Jana; Haugen, Mads H; Rye, Morten Beck; Mælandsmo, Gunhild M; Moestue, Siver A (2019-05-14)
    INTRODUCTION: Glutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione. The drug CB-839 has shown promising effects ...
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    Screening and computational analysis of colorectal associated non-synonymous polymorphism in CTNNB1 gene in Pakistani population 
    Razak, Suhail; Bibi, Nousheen; Dar, Javid Ahmad; Afsar, Tayyaba; Almajwal, Ali; Parveen, Zahida; Jahan, Sarwat (Springer Science and Business Media LLC, 2019-11-07)
    Background: Colorectal cancer (CRC) is categorized by alteration of vital pathways such as β-catenin (CTNNB1) mutations, WNT signaling activation, tumor protein 53 (TP53) inactivation, BRAF, Adenomatous polyposis coli (APC) inactivation, KRAS, dysregulation ...
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    Transplanting embryonic stem cells onto damaged human corneal endothelium 
    Hanson, Charles; Arnarsson, Arsaell; Harðarson, Þórir; Lindgård, Ann; Daneshvarnaeini, Mandana; Ellerström, Catarina; Bruun, Anita; Stenevi, Ulf (Baishideng Publishing Group Inc., 2017)
    AIM To investigate whether human embryonic stem cells (hESCs) could be made to attach, grow and differentiate on a human Descemet’s membrane (DM). METHODS Spontaneously differentiated hESCs were transferred onto a human corneal button with the ...