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Browsing by Subject "Gigtarlæknisfræði"

Browsing by Subject "Gigtarlæknisfræði"

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  • Guðbjörnsson, Björn (2022-07-07)
  • arcOGEN consortium; HUNT All-In Pain; ARGO Consortium; Regeneron Genetics Center; Babis, George C; Cheung, Jason Pui Yin; Kang, Jae Hee; Kraft, Peter; Lietman, Steven A; Samartzis, Dino; Slagboom, P Eline; Stefansson, Kari; Thorsteinsdottir, Unnur; Tobias, Jonathan H; Uitterlinden, André G; Winsvold, Bendik; Zwart, John-Anker; Davey Smith, George; Sham, Pak Chung; Thorleifsson, Gudmar; Gaunt, Tom R; Morris, Andrew P; Valdes, Ana M; Tsezou, Aspasia; Cheah, Kathryn S E; Ikegawa, Shiro; Hveem, Kristian; Esko, Tõnu; Wilkinson, J Mark; Meulenbelt, Ingrid; Lee, Ming Ta Michael; van Meurs, Joyce B J; Styrkársdóttir, Unnur; Zeggini, Eleftheria (2021-09-01)
    Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and identify 100 independently associated risk variants across 11 ...
  • Long, Þórir Einarsson; Indriðason, Ólafur Skúli; Pálsson, Runólfur; Rögnvaldsson, Sæmundur; Löve, Þorvarður Jón; Thorsteinsdóttir, Sigrún; Sverrisdóttir, Ingigerður S; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Sigurðardóttir, Margrét; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Thordardottir, Asdis Rosa; Eyþórsson, Elías Sæbjörn; Jónsson, Ásbjörn; Gíslason, Gauti Kjartan; Ólafsson, Andri; Steingrímsdóttir, Hlíf; Hultcrantz, Malin; Durie, Brian G.M.; Harding, Stephen; Landgren, Ola; Kristinsson, Sigurður Yngvi (2022-09-14)
    Serum free light chain (FLC) concentration is greatly affected by kidney function. Using a large prospective population-based cohort, we aimed to establish a reference interval for FLCs in persons with chronic kidney disease (CKD). A total of 75422 ...
  • Haugen, Ida K.; Felson, David; Abhishek, Abhishek; Berenbaum, Francis; Edwards, John James; Herrero Beaumont, Gabriel; Hermann-Eriksen, Merete; Hill, Catherine L.; Ishimori, Mariko; Jonsson, Helgi; Karjalainen, Teemu; Leung, Ying Ying; Maheu, Emmanuel; Mallen, Christian D.; Moe, Rikke Helene; Ramonda, Roberta; Ritschl, Valentin; Stamm, Tanja A.; Szekanecz, Zoltan; van der Giesen, Florus J.; Ritt, Marco J.P.F.; Wittoek, Ruth; Kjeken, Ingvild; Osteras, Nina; van de Stadt, Lotte A.; Englund, Martin; Dziedzic, Krysia S.; Marshall, M.; Bierma-Zeinstra, Sita; Hansen, Paul; Greibrokk, Elsie; Smeets, Wilma; Kloppenburg, Margreet (2022-02-04)
    ObjectivesIn Phase 1 of developing new hand osteoarthritis (OA) classification criteria, features associated with hand OA were identified in a population with hand complaints. Radiographic findings could better discriminate patients with hand OA and ...
  • Delcoigne, Bénédicte; Provan, Sella Aarrestad; Hammer, Hilde Berner; Di Giuseppe, Daniela; Frisell, Thomas; Glintborg, Bente; Grondal, Gerdur; Gudbjornson, Bjorn; Hetland, Merete Lund; Michelsen, Brigitte; Nordström, Dan; Relas, Heikki; Askling, Johan (2022-02-09)
    OBJECTIVES: To investigate whether patient-reported outcomes vary across countries and are influenced by cultural/contextual factors. Specifically, we aimed to assess inter-country differences in tender joint count (TJC), pain and patient's global ...
  • ICEBIO; Kristjánsdóttir, Signý Rut; Steingrímsdóttir, Þóra; Gröndal, Gerður; Bjarnadóttir, Ragnheiður I.; Einarsdóttir, Kristjana; Guðbjörnsson, Björn (2019-06)
    Inngangur Mikilvægt er að leita frekari þekkingar á meðgöngu og fæðingu hjá konum með liðbólgusjúkdóma. Staðan hérlendis er óþekkt og höfum við því samkeyrt ICEBIO og Fæðingaskrá Embættis landlæknis til að kanna hugsanleg áhrif alvarlegra liðbólgusjúkdóma ...
  • DBDS Genetic Consortium (2022-03-24)
    Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy and has a largely unknown underlying biology. In a genome-wide association study of CTS (48,843 cases and 1,190,837 controls), we found 53 sequence variants at 50 loci associated ...
  • Glintborg, Bente; Di Giuseppe, Daniela; Wallman, Johan K; Provan, Sella A; Nordström, Dan; Hokkanen, Anna-Mari; Österlund, Jenny; Kristianslund, Eirik; Kvien, Tore K; Guðbjörnsson, Björn; Hetland, Merete Lund; Michelsen, Brigitte; Jacobsson, Lennart; Askling, Johan; Lindström, Ulf (2022-06-20)
    OBJECTIVES: The positioning of secukinumab in the treatment of axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) is debated, partly due to a limited understanding of the comparative safety of available treatments. We aimed to assess risk ...
  • Víkingsson, Arnór (2021-02)
  • Karlsdottir, Kristin; Gunnarsdottir, Anna I.; Grondal, Gerdur; Love, Thorvardur J.; Stefansdottir, Elinborg; Davidsdottir, Loa G.; Thorleifsdottir, Ragna H.; Gudbjornsson, Bjorn (2022-01-27)
    Objective: Due to a tender process in Iceland, all patients on Humira® were switched nationwide to its biosimilar Imraldi® in March 2019. The study aimed to explore the patient's perspective of the Humira® and Imraldi® injection devices. Methods: A ...
  • Ørnbjerg, Lykke Midtbøll; Linde, Louise; Georgiadis, Stylianos; Horskjær Rasmussen, Simon; Lindström, Ulf; Askling, Johan; Michelsen, Brigitte; Di Giuseppe, Daniela; Wallman, Johan K.; Pavelka, Karel; Závada, Jakub; Nissen, Michael J; Jones, Gareth T.; Relas, Heikki; Pirilä, Laura; Tomšič, Matija; Rotar, Ziga; Geirsson, Árni Jón; Guðbjörnsson, Björn; Kristianslund, Eirik K.; van sder Horst-Bruinsma, Irene; Loft, Anne Gitte; Laas, Karin; Iannone, Florenzo; Corrado, Addolorata; Ciurea, Adrian; Santos, Maria José; Santos, Helena; Codreanu, Catalin; Akkoc, Nurullah; Gunduz, Ozgul S.; Glintborg, Bente; Østergaard, Mikkel; Lund Hetland, Merete (2022-10-01)
    Objectives: In patients with axial spondyloarthritis (axSpA) initiating their first tumor necrosis factor alpha-inhibitor (TNFi), we aimed to identify common baseline predictors of Ankylosing Spondylitis Disease Activity Score (ASDAS-CRP) inactive ...
  • Nielsen, K.R.; Pedersen, O.B.; Sørensen, E.; Ostrowski, S.; Johansson, P.I.; Gudbjartsson, D.; Stefansson, H.; Larsen, M.A.H.; Didriksen, M.; Sækmose, S.; Zeggini, E.; Hatzikotoulas, K.; Southam, L.; Gilly, A.; Barysenka, A.; van Meurs, J.B.J.; Boer, C.G.; Uitterlinden, A.G.; Styrkársdóttir, U.; Stefánsdóttir, L.; Esko, T.; Mägi, R.; Teder-Laving, M.; Ikegawa, S.; Terao, C.; Takuwa, H.; Meulenbelt, I.; Coutinho de Almeida, R.; Kloppenburg, M.; Tuerlings, M.; Slagboom, P.E.; Nelissen, R.R.G.H.H.; Valdes, A.M.; Mangino, M.; Tsezou, A.; Zengini, E.; Alexiadis, G.; Babis, G.C.; Cheah, K.S.E.; Wu, T.T.; Samartzis, D.; Cheung, J.P.Y.; Sham, P.C.; Kraft, P.; Kang, J.H.; Hveem, K.; Zwart, J.-A.; Luetge, A.; Skogholt, A.H.; Johnsen, M.B.; Thomas, L.F.; Winsvold, B.; Gabrielsen, M.E.; Lee, M.T.M.; Zhang, Y.; Lietman, S.A.; Shivakumar, M.; Smith, G.D.; Tobias, J.H.; Hartley, A.; Gaunt, T.R.; Zheng, J.; Wilkinson, J.M.; Steinberg, J.; Morris, A.P.; Ulfarsson, E.; Blondal, J.; Brunak, S.; Ostrowski, S.R.; Ullum, H.; Þorsteinsdóttir, U.; Stefansson, H.; Gudbjartsson, D.F.; Thorgeirsson, T.E.; Stefansson, K.; DBDS Genetic Consortium; GO Consortium (2022-02-02)
    Back pain is a common and debilitating disorder with largely unknown underlying biology. Here we report a genome-wide association study of back pain using diagnoses assigned in clinical practice; dorsalgia (119,100 cases, 909,847 controls) and ...
  • Michelsen, Brigitte; Georgiadis, Stylianos; Di Giuseppe, Daniela; Loft, Anne G.; Nissen, Michael J.; Iannone, Florenzo; Pombo-Suarez, Manuel; Mann, Herman; Rotar, Ziga; Eklund, Kari K.; Kvien, Tore K.; Santos, Maria J.; Guðbjörnsson, Björn; Codreanu, Catalin; Yilmaz, Sema; Wallman, Johan K.; Brahe, Cecilie H.; Möller, Burkhard; Favalli, Ennio G.; Sánchez-Piedra, Carlos; Nekvindova, Lucie; Tomsic, Matija; Trokovic, Nina; Kristianslund, Eirik K.; Santos, Helena; Löve, Þorvarður Jón; Ionescu, Ruxandra; Pehlivan, Yavuz; Jones, Gareth T.; van der Horst-Bruinsma, Irene; Ørnbjerg, Lykke M.; Østergaard, Mikkel; Hetland, Merete L. (2022-04-29)
    Objective: There is a lack of real-life studies on interleukin-17 (IL-17) inhibition in psoriatic arthritis (PsA). We assessed real-life 6- and 12-month effectiveness (i.e., retention, remission, low disease activity [LDA], and response rates) of the ...
  • Axelsson, Gísli Þór; Halldorsson, Arnljotur Bjorn; Jónsson, Helgi; Eyþórsson, Elías Sæbjörn; Sigurðardóttir, Erla Sigríður; Harðardóttir, Hrönn; Guðmundsson, Gunnar; Hansdóttir, Sif (2022-10-01)
    INTRODUCTION: Considering the pulmonary burden caused by acute COVID-19, questions remain of respiratory consequences after recovery. The aim of the study was to describe respiratory function of COVID-19 pneumonia survivors at mid-term follow-up (median ...
  • Almeida-Brasil, Celline C; Hanly, John G; Urowitz, Murray; Clarke, Ann Elaine; Ruiz-Irastorza, Guillermo; Gordon, Caroline; Ramsey-Goldman, Rosalind; Petri, Michelle; Ginzler, Ellen M; Wallace, Daniel J; Bae, Sang-Cheol; Romero-Diaz, Juanita; Dooley, Mary Anne; Peschken, Christine; Isenberg, David; Rahman, Anisur; Manzi, Susan; Jacobsen, Søren; Sam Lim, Sung; Van vollenhoven, Ronald F.; Nived, Ola; Jönsen, Andreas; Kamen, Diane L; Aranow, Cynthia; Sánchez-Guerrero, Jorge; Gladman, Dafna D.; Fortin, Paul R; Alarcon, Graciela S.; Merrill, Joan T; Kalunian, Kenneth; Ramos-Casals, Manuel; Steinsson, Kristján; Zoma, A A; Askanase, Anca D; Khamashta, Munther; Bruce, Ian N.; Inanc, Murat; Lukusa, Luck; Bernatsky, Sasha (2022-11-01)
    Objective To evaluate hydroxychloroquine (HCQ)-related retinal toxicity in the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort. Methods Data were collected at annual study visits between 1999 and 2019. We followed patients ...
  • Arnadottir, Berglind; Gröndal, Gerður María; Tryggvason, Þórður; Guðbjörnsson, Björn (2021-12)
    Sumarið 2020 leitaði kona á níræðisaldri til læknis vegna höfuðverks og sjóntruflana. Greining var óljós og einkenni versnuðu hratt. Hún varð blind á báðum augum og fékk stórt drep í hársvörðinn. Um var að ræða hröð versnandi einkenni risafrumuæðabólgu ...
  • Haraldsdóttir, Sigríður Ólína; Jonasson, Jon Gunnlaugur; Jorundsdottir, Kristin Bara; Hannesson, Haraldur Jon; Gislason, Thorarinn; Gudbjornsson, Bjorn (2021-10-01)
    Background This nationwide study aimed to elucidate the incidence and clinical characteristics of tissueverified sarcoidosis in Iceland. A secondary aim was to analyse sex differences and identify possible environmental factors contributing to the ...
  • Thors, Valtýr Stefánsson; Björnsdóttir, Kristín; Löve, Þorvarður Jón; Haraldsson, Ásgeir (2022-07-08)
    Introduction: Children are less likely to acquire SARS-CoV-2 infections than adults and when infected, usually have milder disease. True infection and complication rates are, however, difficult to ascertain. In Iceland, a strict test, trace and isolate ...
  • DBDS Genetic Consortium (2022-07-20)
    Detailed knowledge of how diversity in the sequence of the human genome affects phenotypic diversity depends on a comprehensive and reliable characterization of both sequences and phenotypic variation. Over the past decade, insights into this relationship ...