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Browsing by Subject "Geriatrics and Gerontology"

Browsing by Subject "Geriatrics and Gerontology"

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    Associations of Pulmonary Function with MRI Brain Volumes : A Coordinated Multi-Study Analysis 
    Frenzel, Stefan; Bis, Joshua C.; Gudmundsson, Elias F.; O'Donnell, Adrienne; Simino, Jeannette; Yaqub, Amber; Bartz, Traci M.; Brusselle, Guy G.O.; Bülow, Robin; DeCarli, Charles S.; Ewert, Ralf; Gharib, Sina A.; Ghosh, Saptaparni; Gireud-Goss, Monica; Gottesman, Rebecca F.; Ikram, M. Arfan; Knopman, David S.; Launer, Lenore J.; London, Stephanie J.; Longstreth, W. T.; Lopez, Oscar L.; Melo van Lent, Debora; O'Connor, George; Satizabal, Claudia L.; Shrestha, Srishti; Sigurdsson, Sigurdur; Stubbe, Beate; Talluri, Rajesh; Vasan, Ramachandran S.; Vernooij, Meike W.; Völzke, Henry; Wiggins, Kerri L.; Yu, Bing; Beiser, Alexa S.; Gudnason, Vilmundur; Mosley, Thomas; Psaty, Bruce M.; Wolters, Frank J.; Grabe, Hans J.; Seshadri, Sudha (2022-11-22)
    BACKGROUND: Previous studies suggest poor pulmonary function is associated with increased burden of cerebral white matter hyperintensities and brain atrophy among elderly individuals, but the results are inconsistent. OBJECTIVE: To study the cross-sectional ...
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    Cerebrospinal Fluid C18 Ceramide Associates with Markers of Alzheimer's Disease and Inflammation at the Pre- And Early Stages of Dementia 
    Teitsdóttir, Unnur Diljá; Halldórsson, Skarphéðinn; Rolfsson, Óttar; Lund, Sigrún H.; Jónsdóttir, María Kristín; Snædal, Jón G.; Petersen, Pétur Henry (2021-05-04)
    BACKGROUND: Understanding how dysregulation in lipid metabolism relates to the severity of Alzheimer's disease (AD) pathology might be critical in developing effective treatments. OBJECTIVE: To identify lipid species in cerebrospinal fluid (CSF) ...
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    Cognition and brain health among older adults in Iceland : the AGES-Reykjavik study 
    Valsdóttir, Vaka; Magnúsdóttir, Brynja Björk; Chang, Milan; Sigurdsson, Sigurdur; Guðnason, Vilmundur G; Launer, Lenore J.; Jónsdóttir, María Kristín (2022-12)
    The paper aimed to compare how factors previously identified as predictive factors for cognitive decline and dementia related to cognitive performance on the one hand and brain health on the other. To that aim, multiple linear regression was applied ...
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    Comparative study of machine learning methods for modeling associations between risk factors and future dementia cases 
    Valsdóttir, Vaka; Jónsdóttir, María Kristín; Magnúsdóttir, Brynja Björk; Chang, Milan; Hu, Yi Han; Gudnason, Vilmundur; Launer, Lenore J.; Stefánsson, Hlynur (2024-02)
    A substantial portion of dementia risk can be attributed to modifiable risk factors that can be affected by lifestyle changes. Identifying the contributors to dementia risk could prove valuable. Recently, machine learning methods have been increasingly ...
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    Deprescribing practices, habits and attitudes of geriatricians and geriatricians-in-training across Europe : a large web-based survey 
    On Behalf of the EuGMS SIG Pharmacology (2022-12)
    Purpose: To provide an overview of the current deprescribing attitudes, practices, and approaches of geriatricians and geriatricians-in-training across Europe. Methods: An online survey was disseminated among European geriatricians and geriatricians- ...
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    Determinants of physical function in community dwelling old people 
    Geirsdottir, Olöf G.; Chang, Milan; Briem, Kristin; Jonsson, Pálmi V.; Thorsdottir, Inga; Ramel, Alfonso (2022-03)
    Background. Poor physical function is associated with disability and mortality in old people. Objectives. The aim was to find determinants of physical function in old people. Design. Secondary, cross-sectional analysis. Setting. Community in the ...
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    Diabetes mellitus increases risk of adverse drug reactions and death in hospitalised older people : the SENATOR trial 
    Chinmayee, Anagha; Subbarayan, Selvarani; Myint, Phyo Kyaw; Cherubini, Antonio; Cruz-Jentoft, Alfonso J.; Petrovic, Mirko; Guðmundsson, Aðalsteinn; Byrne, Stephen; O’Mahony, Denis; Soiza, Roy L. (2024-02)
    PURPOSE: Adverse drug reactions (ADRs) are a major cause of morbidity and mortality, especially in older people. Older people with diabetes mellitus may be at especially high risk of ADRs but this risk has not been well studied. This study aimed to ...
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    Does antipsychotic use mediate the effect of psychiatric disorders on COVID-19? – Authors' reply 
    Yang, Huazhen; Chen, Wenwen; Fang, Fang; Valdimarsdóttir, Unnur A.; Song, Huan (2021-02)
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    The importance of different frailty domains in a population based sample in England 
    Arnadottir, Solveig A.; Bruce, Julie; Lall, Ranjit; Withers, Emma J.; Underwood, Martin; Shaw, Fiona; Sheridan, Ray; Hossain, Anower; Lamb, Sarah E.; Martin, Finbarr; Yardley, Lucy; Skelton, Dawn; Willett, Keith; Eldridge, Sandra; Slowther, Anne Marie; Duggan, Sarah; Bruce, Julie; Hennings, Susie; Withers, Emma; Mant, Rhys; Rai, Rishpal; Turner, Craig; Andrews, Agata; Fearn, Rachael; Finnegan, Susanne; Walker, Nicola; Potter, Rachel; Lall, Ranjit; Hulme, Claire; Bojke, Chris; Longo, Roberta; Finnegan, Susanne; Westacott, Katherine; Ralhan, Shvaita; Sheridan, Ray; Treml, Jonathan; Sheridan, Ray; Riglin, Jackie; Gordjin, Harm; Dutta, Ruma; Burns, Jo; Treml, Jonathan; Shaw, Fiona; Davison, John; Willis, Ade; Muthiah, Chocks; Adjei, Henry (2020-01-15)
    Background: The aim was to estimate the prevalence of frailty and relative contribution of physical/balance, nutritive, cognitive and sensory frailty to important adverse health states (falls, physical activity levels, outdoor mobility, problems in ...
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    Obesity, Physical Function, and Training Success in Community-Dwelling Nonsarcopenic Old Adults 
    Geirsdottir, Olof; Chang, Milan; Jónsson, Pálmi V.; Thorsdottir, Inga; Ramel, Alfons (Hindawi Limited, 2019-02-18)
    Objectives. Obesity-related physiological changes can limit improvements of obese subjects after training. The aim was to investigate obesity, muscular strength, and physical function in community-dwelling nonsarcopenic old adults. Methods. Nonsarcopenic ...
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    Optimizing pharmacotherapy and deprescribing strategies in older adults living with multimorbidity and polypharmacy : EuGMS SIG on pharmacology position paper 
    EuGMS SIG Pharmacology (2023-12)
    Inappropriate polypharmacy is highly prevalent among older adults and presents a significant healthcare concern. Conducting medication reviews and implementing deprescribing strategies in multimorbid older adults with polypharmacy are an inherently ...
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    Predicting unplanned hospital visits in older home care recipients : a cross-country external validation study 
    Klunder, Jet H.; Bordonis, Veronique; Heymans, Martijn W.; van der Roest, Henriëtte G.; Declercq, Anja; Smit, Jan H.; Garms-Homolova, Vjenka; Jónsson, Pálmi V.; Finne-Soveri, Harriet; Onder, Graziano; Joling, Karlijn J.; Maarsingh, Otto R.; van Hout, Hein P.J. (2021-10-14)
    Background: Accurate identification of older persons at risk of unplanned hospital visits can facilitate preventive interventions. Several risk scores have been developed to identify older adults at risk of unplanned hospital visits. It is unclear ...
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    Prescription opioids among older adults : ten years of data across five countries 
    Hamina, A.; Muller, A. E.; Clausen, T.; Skurtveit, S.; Hesse, M.; Tjagvad, C.; Thylstrup, B.; Odsbu, I.; Zoega, H.; Jónsdóttir, Harpa Lind; Taipale, H. (2022-05-16)
    Abstract: Background: Opioid use has increased globally in the recent decade. Although pain remains a significant problem among older adults, susceptibility to opioid-related harms highlights the importance of careful opioid therapy monitoring on ...
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    Pre-pandemic psychiatric disorders and risk of COVID-19 : a UK Biobank cohort analysis 
    Yang, Huazhen; Chen, Wenwen; Hu, Yao; Chen, Yilong; Zeng, Yu; Sun, Yajing; Ying, Zhiye; He, Junhui; Qu, Yuanyuan; Lu, Donghao; Fang, Fang; Valdimarsdóttir, Unnur Anna; Song, Huan (2020-11)
    Background: Psychiatric morbidities have been associated with a risk of severe infections through compromised immunity, health behaviours, or both. However, data are scarce on the association between multiple types of pre-pandemic psychiatric disorders ...
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    Resilience among older adults living at home : Urban-rural difference in a population-based study 
    Sigurðardóttir, Árún Kristín; Steingrimsson, Jon A.; Kristófersson, Gísli Kort; Gunnarsdóttir, Elín Díanna (2022-12)
    Objective. We examined how individual and contextual factors affect resilience in community-dwelling older adults living in urban or rural areas in Northern Iceland. Methods. A cross-sectional study, conducted from 2017–2018, ran-domly sampled ...
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    Sex differences in brain atrophy in dementia with Lewy bodies 
    Oltra, Javier; Habich, Annegret; Schwarz, Christopher G.; Nedelska, Zuzana; Przybelski, Scott A.; Inguanzo, Anna; Diaz-Galvan, Patricia; Lowe, Val J.; Oppedal, Ketil; Gonzalez, Maria C.; Philippi, Nathalie; Blanc, Frederic; Barkhof, Frederik; Lemstra, Afina W.; Hort, Jakub; Padovani, Alessandro; Rektorova, Irena; Bonanni, Laura; Massa, Federico; Kramberger, Milica G.; Taylor, John Paul; Snædal, Jón G; Walker, Zuzana; Antonini, Angelo; Dierks, Thomas; Segura, Barbara; Junque, Carme; Westman, Eric; Boeve, Bradley F.; Aarsland, Dag; Kantarci, Kejal; Ferreira, Daniel (2023-12-22)
    INTRODUCTION: Sex influences neurodegeneration, but it has been poorly investigated in dementia with Lewy bodies (DLB). We investigated sex differences in brain atrophy in DLB using magnetic resonance imaging (MRI). METHODS: We included 436 patients ...
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    STOPP/START criteria for potentially inappropriate prescribing in older people : version 3 
    O'Mahony, Denis; Cherubini, Antonio; Guiteras, Anna Renom; Denkinger, Michael; Beuscart, Jean-Baptiste; Onder, Graziano; Guðmundsson, Aðalsteinn; Cruz-Jentoft, Alfonso J; Knol, Wilma; Bahat, Gülistan; van der Velde, Nathalie; Petrovic, Mirko; Curtin, Denis (2023-08)
    PURPOSE: STOPP/START is a physiological systems-based explicit set of criteria that attempts to define the clinically important prescribing problems relating to potentially inappropriate medications (PIMs-STOPP criteria) and potential prescribing ...
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    A systematic review and meta-analysis comparing the effect of aquatic and land exercise on dynamic balance in older adults 
    Vakula, Michael N.; Waller, Benjamin; Bressel, Eadric; Kim, Youngwook (Springer Science and Business Media LLC, 2020-08-25)
    Abstract Background: Balance impairments are the leading causes of falls in older adults. Aquatic-based exercises have been broadly practiced as an alternative to land-based exercises; however, the effects on dynamic balance have not been comprehensively ...
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    A Systematic Review of the Current Evidence from Randomised Controlled Trials on the Impact of Medication Optimisation or Pharmacological Interventions on Quantitative Measures of Cognitive Function in Geriatric Patients 
    Pazan, Farhad; Petrovic, Mirko; Cherubini, Antonio; Cruz-Jentoft, Alfonso J.; Denkinger, Michael; van der Cammen, Tischa J.M.; Stevenson, Jennifer M.; Ibrahim, Kinda; Rajkumar, Chakravarthi; Bakken, Marit Stordal; Crome, Peter; Guðmundsson, Aðalsteinn; Knol, Wilma; Snijders, Birgitta M.G.; O’Mahony, Denis; Serra-Rexach, José Antonio; Soulis, George; van Marum, Rob J.; Ziere, Gijsbertus; Mair, Alpana; Burkhardt, Heinrich; Neumann-Podczaska, Agnieszka; Wieczorowska-Tobis, Katarzyna; Fernandes, Marilia Andreia; Gruner, Heidi; van der Velde, Nathalie; Wehling, Martin (2022-11)
    Background: Cognitive decline is common in older people. Numerous studies point to the detrimental impact of polypharmacy and inappropriate medication on older people’s cognitive function. Here we aim to systematically review evidence on the impact of ...