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Fletta eftir efnisorði "Genome-Wide Association Study"

Fletta eftir efnisorði "Genome-Wide Association Study"

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  • Shah, Sonia; Gudbjartsson, Daniel; Thorsteinsdottir, Unnur; Stefansson, Kari (Springer Science and Business Media LLC, 2020-01-09)
    Heart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) have yielded only limited insights, leaving ...
  • van Setten, Jessica; Brody, Jennifer A.; Jamshidi, Yalda; Swenson, Brenton R.; Butler, Anne M.; Campbell, Harry; Del Greco, Fabiola M.; Evans, Daniel S.; Gibson, Quince; Gudbjartsson, Daniel; Kerr, Kathleen F.; Krijthe, Bouwe P.; Lyytikäinen, Leo-Pekka; Müller, Christian; Müller-Nurasyid, Martina; Nolte, Ilja M.; Padmanabhan, Sandosh; Ritchie, Marylyn D.; Robino, Antonietta; Smith, Albert Vernon; Steri, Maristella; Tanaka, Toshiko; Teumer, Alexander; Trompet, Stella; Ulivi, Sheila; Verweij, Niek; Yin, Xiaoyan; Arnar, Davíð O.; Asselbergs, Folkert W.; Bader, Joel S.; Barnard, John; Bis, Josh; Blankenberg, Stefan; Boerwinkle, Eric; Bradford, Yuki; Buckley, Brendan M.; Chung, Mina K.; Crawford, Dana; den Hoed, Marcel; Denny, Josh C.; Dominiczak, Anna F.; Ehret, Georg B.; Eijgelsheim, Mark; Ellinor, Patrick T.; Felix, Stephan B.; Franco, Oscar H.; Franke, Lude; Harris, Tamara B.; Holm, Hilma; Ilaria, Gandin; Iorio, Annamaria; Kähönen, Mika; Kolcic, Ivana; Kors, Jan A.; Lakatta, Edward G.; Launer, Lenore J.; Lin, Honghuang; Lin, Henry J.; Loos, Ruth J. F.; Lubitz, Steven A.; Macfarlane, Peter W.; Magnani, Jared W.; Leach, Irene Mateo; Meitinger, Thomas; Mitchell, Braxton D.; Munzel, Thomas; Papanicolaou, George J.; Peters, Annette; Pfeufer, Arne; Pramstaller, Peter P.; Raitakari, Olli T.; Rotter, Jerome I.; Rudan, Igor; Samani, Nilesh J.; Schlessinger, David; Silva Aldana, Claudia T.; Sinner, Moritz F.; Smith, Jonathan D.; Snieder, Harold; Soliman, Elsayed Z.; Spector, Timothy D.; Stott, David J.; Strauch, Konstantin; Tarasov, Kirill V.; Þorsteinsdóttir, Unnur; Uitterlinden, Andre G.; Van Wagoner, David R.; Völker, Uwe; Völzke, Henry; Waldenberger, Melanie; Jan Westra, Harm; Wild, Philipp S.; Zeller, Tanja; Alonso, Alvaro; Avery, Christy L.; Bandinelli, Stefania; Benjamin, Emelia J.; Cucca, Francesco; Dörr, Marcus; Ferrucci, Luigi; Gasparini, Paolo; Gudnason, Vilmundur; Hayward, Caroline; Heckbert, Susan R.; Hicks, Andrew A.; Jukema, J. Wouter; Kääb, Stefan; Lehtimäki, Terho; Liu, Yongmei; Munroe, Patricia B.; Parsa, Afshin; Polasek, Ozren; Psaty, Bruce M.; Roden, Dan M.; Schnabel, Renate B.; Sinagra, Gianfranco; Stefansson, Kari; Stricker, Bruno H.; van der Harst, Pim; van Duijn, Cornelia M.; Wilson, James F.; Gharib, Sina A.; de Bakker, Paul I. W.; Isaacs, Aaron; Arking, Dan E.; Sotoodehnia, Nona (Springer Science and Business Media LLC, 2018-07-25)
    Electrocardiographic PR interval measures atrio-ventricular depolarization and conduction, and abnormal PR interval is a risk factor for atrial fibrillation and heart block. Our genome-wide association study of over 92,000 European-descent individuals ...
  • Nielsen, K.R.; Pedersen, O.B.; Sørensen, E.; Ostrowski, S.; Johansson, P.I.; Gudbjartsson, D.; Stefansson, H.; Larsen, M.A.H.; Didriksen, M.; Sækmose, S.; Zeggini, E.; Hatzikotoulas, K.; Southam, L.; Gilly, A.; Barysenka, A.; van Meurs, J.B.J.; Boer, C.G.; Uitterlinden, A.G.; Styrkársdóttir, U.; Stefánsdóttir, L.; Esko, T.; Mägi, R.; Teder-Laving, M.; Ikegawa, S.; Terao, C.; Takuwa, H.; Meulenbelt, I.; Coutinho de Almeida, R.; Kloppenburg, M.; Tuerlings, M.; Slagboom, P.E.; Nelissen, R.R.G.H.H.; Valdes, A.M.; Mangino, M.; Tsezou, A.; Zengini, E.; Alexiadis, G.; Babis, G.C.; Cheah, K.S.E.; Wu, T.T.; Samartzis, D.; Cheung, J.P.Y.; Sham, P.C.; Kraft, P.; Kang, J.H.; Hveem, K.; Zwart, J.-A.; Luetge, A.; Skogholt, A.H.; Johnsen, M.B.; Thomas, L.F.; Winsvold, B.; Gabrielsen, M.E.; Lee, M.T.M.; Zhang, Y.; Lietman, S.A.; Shivakumar, M.; Smith, G.D.; Tobias, J.H.; Hartley, A.; Gaunt, T.R.; Zheng, J.; Wilkinson, J.M.; Steinberg, J.; Morris, A.P.; Ulfarsson, E.; Blondal, J.; Brunak, S.; Ostrowski, S.R.; Ullum, H.; Þorsteinsdóttir, U.; Stefansson, H.; Gudbjartsson, D.F.; Thorgeirsson, T.E.; Stefansson, K.; DBDS Genetic Consortium; GO Consortium (2022-02-02)
    Back pain is a common and debilitating disorder with largely unknown underlying biology. Here we report a genome-wide association study of back pain using diagnoses assigned in clinical practice; dorsalgia (119,100 cases, 909,847 controls) and ...
  • Einarsson, Gudmundur; Thorleifsson, Gudmar; Steinthorsdottir, Valgerdur; Zink, Florian; Helgason, Hannes; Olafsdottir, Thorhildur; Rognvaldsson, Solvi; Tragante, Vinicius; Ulfarsson, Magnus O; Sveinbjornsson, Gardar; Snaebjarnarson, Audunn S; Einarsson, Hafsteinn; Ægisdóttir, Hildur Margrét; Jonsdottir, Gudrun A; Helgadottir, Anna; Gretarsdottir, Solveig; Styrkarsdottir, Unnur; Arnason, Hannes K; Bjarnason, Ragnar Grímur; Sigurdsson, Emil; Arnar, Davíð Ottó; Björnsson, Einar Stefán; Pálsson, Runólfur; Bjornsdottir, Gyda; Stefansson, Hreinn; Thorgeirsson, Thorgeir; Sulem, Patrick; Þorsteinsdóttir, Unnur; Holm, Hilma; Gudbjartsson, Daniel F; Stefánsson, Kári (2024-11-12)
    Mendelian Randomization studies indicate that BMI contributes to various diseases, but it's unclear if this is entirely mediated by BMI itself. This study examines whether disease risk from BMI-associated sequence variants is mediated through BMI or ...
  • Ólafsdóttir, Þórunn Ásta; Thorleifsson, Gudmar; Lopez de Lapuente Portilla, Aitzkoa; Jonsson, Stefan; Stefánsdóttir, Lilja; Niroula, Abhishek; Jonasdottir, Aslaug; Eggertsson, Hannes P.; Halldórsson, Gísli Hreinn; Thorlacius, Gudny E.; Arnthorsson, Asgeir O.; Björnsdóttir, Unnur Steina; Asselbergs, Folkert W.; Bentlage, Arthur E.H.; Eyjolfsson, Gudmundur I.; Gudmundsdottir, Steinunn; Gunnarsdottir, Kristbjorg; Halldórsson, Bjarni Vilhjálmur; Holm, Hilma; Lúðvíksson, Björn Rúnar; Melsted, Páll; Norddahl, Gudmundur L.; Ólafsson, Ísleifur; Saevarsdottir, Saedis; Sigurdardottir, Olof; Sigurdsson, Asgeir; Temming, Robin; Önundarson, Páll Torfi; Þorsteinsdóttir, Unnur; Vidarsson, Gestur; Sulem, Patrick; Gudbjartsson, Daniel F.; Jónsdóttir, Ingileif; Nilsson, Björn; Stefánsson, Kári (2024-12)
    Immunoglobulin G (IgG) is the main isotype of antibody in human blood. IgG consists of four subclasses (IgG1 to IgG4), encoded by separate constant region genes within the Ig heavy chain locus (IGH). Here, we report a genome-wide association study on ...