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Browsing by Subject "Endocrinology, Diabetes and Metabolism"

Browsing by Subject "Endocrinology, Diabetes and Metabolism"

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    Age, Sex, Body Mass Index, Diet and Menopause Related Metabolites in a Large Homogeneous Alpine Cohort 
    Hernandes, Vinicius Verri; Dordevic, Nikola; Hantikainen, Essi Marjatta; Sigurðsson, Baldur Bragi; Smárason, Sigurður Vidir; Garcia-Larsen, Vanessa; Gögele, Martin; Caprioli, Giulia; Bozzolan, Ilaria; Pramstaller, Peter P.; Rainer, Johannes (2022-02-24)
    Metabolomics in human serum samples provide a snapshot of the current metabolic state of an individuum. Metabolite concentrations are influenced by both genetic and environmental factors. Concentrations of certain metabolites can further depend on age, ...
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    Automated Cancer Diagnostics via Analysis of Optical and Chemical Images by Deep and Shallow Learning 
    Ísberg, Ólöf Gerður; Giunchiglia, Valentina; McKenzie, James S.; Takats, Zoltan; Jónasson, Jón Gunnlaugur; Bodvarsdottir, Sigridur Klara; Þorsteinsdóttir, Margrét; Xiang, Yuchen (2022-05-18)
    Optical microscopy has long been the gold standard to analyse tissue samples for the diagnostics of various diseases, such as cancer. The current diagnostic workflow is time-consuming and labour-intensive, and manual annotation by a qualified pathologist ...
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    Cardiovascular complications of diabetes : role of non-coding RNAs in the crosstalk between immune and cardiovascular systems 
    Spinetti, Gaia; Mutoli, Martina; Greco, Simona; Riccio, Federica; Ben-Aicha, Soumaya; Kenneweg, Franziska; Jusic, Amela; de Gonzalo-Calvo, David; Nossent, Anne Yaël; Novella, Susana; Kararigas, Georgios; Thum, Thomas; Emanueli, Costanza; Devaux, Yvan; Martelli, Fabio (2023-05-24)
    Diabetes mellitus, a group of metabolic disorders characterized by high levels of blood glucose caused by insulin defect or impairment, is a major risk factor for cardiovascular diseases and related mortality. Patients with diabetes experience a state ...
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    Early pregnancy plasma fatty acid profiles of women later diagnosed with gestational diabetes 
    Tryggvadóttir, Ellen Alma; Gunnarsdóttir, Ingibjörg; Birgisdóttir, Bryndís Eva; Hrólfsdottir, Laufey; Landberg, Rikard; Hreiðarsdóttir, Ingibjörg Th; Harðardóttir, Hildur; Halldórsson, Þórhallur Ingi; Gunnarsdottir, Ingibjorg; Hardardottir, Hildur; Halldorsson, Thorhallur Ingi (2021-08-04)
    Introduction Fatty acid (FA) concentrations have previously been associated with gestational diabetes mellitus (GDM). However, few studies on GDM have examined FA profiles in early pregnancy or before diagnosis. This study aimed to compare early pregnancy ...
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    Editorial : New Insights into Estrogen/Estrogen Receptor Effects in the Cardiac and Skeletal Muscle 
    Lowe, Dawn A.; Kararigas, Georgios (2020-03-19)
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    High risk of malnutrition among hospitalised coronavirus disease 2019 (COVID-19) patients is associated with mortality and other clinical outcomes 
    Guðnadóttir, Sandra Dögg; Gunnarsdóttir, Ingibjörg; Hernandez, Ubaldo Benitez; Ingadóttir, Áróra Rós (2024-06)
    Introduction: Increasing evidence indicates an association between nutritional status and Coronavirus disease 2019 (COVID-19) disease severity. The aim of the study was to describe the risk of malnutrition, body mass index (BMI) and vitamin D status ...
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    HOMEFOOD randomised trial - Six-month nutrition therapy improves quality of life, self-rated health, cognitive function, and depression in older adults after hospital discharge 
    Blondal, B S; Geirsdottir, O G; Halldorsson, T I; Beck, A M; Jónsson, Pálmi V; Ramel, A (2022-04-01)
    Background and aims: Malnutrition is common among older adults and is related to quality of life, cognitive function, and depression. To what extent nutrition interventions can improve these outcomes remains unclear. The aim of this study was to ...
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    Liraglutide changes body composition and lowers added sugar intake in overweight persons with insulin pump-treated type 1 diabetes 
    Schmidt, Signe; Frandsen, Christian S.; Dejgaard, Thomas F.; Vistisen, Dorte; Halldórsson, Þórhallur Ingi; Olsen, Sjudur F.; Jensen, Jens Erik B.; Madsbad, Sten; Andersen, Henrik U.; Nørgaard, Kirsten (2021-09-30)
    Aims: To present secondary outcome analyses of liraglutide treatment in overweight adults with insulin pump-treated type 1 diabetes (T1D), focusing on changes in body composition and dimensions, and to evaluate changes in food intake to identify potential ...
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    Monoamine oxidase A activity in fibroblasts as a functional confirmation of MAOA variants 
    Peters, Tessa M.A.; Lammerts van Bueren, Irma; Geurtz, Ben P.B.H.; Coene, Karlien L.M.; de Leeuw, Nicole; Brunner, Han G.; Jónsson, Jón Jóhannes; Willemsen, Michèl A.A.P.; Wevers, Ron A.; Verbeek, Marcel M. (2020-12-28)
    Monoamine oxidase A (MAO‐A) deficiency is a rare inborn error of metabolism with impaired degradation of biogenic amines including 5‐hydroxytryptamine (5‐HT), resulting in borderline intellectual disability and behavioral abnormalities. Genetic variants ...
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    Naturally occurring glycosidases in milk from native cattle breeds : Activity and consequences on free and protein bound-glycans 
    Sunds, Anne Vuholm; Roland, Ida Schwartz; Sundekilde, Ulrik Kræmer; Thesbjerg, Martin Nørmark; Robinson, Randall; Bunyatratchata, Apichaya; Glantz, Maria; Paulsson, Marie; Leskauskaite, Daiva; Pihlanto, Anne; Inglingstad, Ragnhild; Devold, Tove Gulbrandsen; Vegarud, Gerd Elisabeth; Birgisdóttir, Bryndís Eva; Guðjónsdóttir, María; Barile, Daniela; Larsen, Lotte Bach; Poulsen, Nina Aagaard (2021-09-28)
    Little is known about the extent of variation and activity of naturally occurring milk glycosidases and their potential to degrade milk glycans. A multi-omics approach was used to investigate the relationship between glycosidases and important bioactive ...
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    Nordic dietary patterns and cardiometabolic outcomes : a systematic review and meta-analysis of prospective cohort studies and randomised controlled trials 
    Massara, Paraskevi; Zurbau, Andreea; Glenn, Andrea J.; Chiavaroli, Laura; Khan, Tauseef A.; Viguiliouk, Effie; Mejia, Sonia Blanco; Comelli, Elena M.; Chen, Victoria; Schwab, Ursula; Risérus, Ulf; Uusitupa, Matti; Aas, Anne Marie; Hermansen, Kjeld; Thorsdottir, Inga; Rahelić, Dario; Kahleová, Hana; Salas-Salvadó, Jordi; Kendall, Cyril W.C.; Sievenpiper, John L. (2022-08-26)
    AIMS/HYPOTHESIS: Nordic dietary patterns that are high in healthy traditional Nordic foods may have a role in the prevention and management of diabetes. To inform the update of the EASD clinical practice guidelines for nutrition therapy, we conducted ...
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    Pituitary dysfunction following mild traumatic brain injury in female athletes 
    Claessen, Lára Ósk Eggertsdóttir; Kristjánsdóttir, Hafrún; Jónsdóttir, María Kristín; Lund, Sigrún Helga; Kristensen, Ingunn Unnsteinsdóttir; Sigurjónsdóttir, Helga Ágústa (2024-02)
    Objective: Pituitary dysfunction following mild traumatic brain injury can have serious physical and psychological consequences, making correct diagnosis and treatment essential. To the best of our knowledge, this study is the first to study the ...
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    Premature menopause and autoimmune primary ovarian insufficiency in two international multi-center cohorts 
    Vogt, Elinor Chelsom; Real, Francisco Gómez; Husebye, Eystein Sverre; Björnsdottir, Sigridur; Benediktsdóttir, Bryndís; Bertelsen, Randi Jacobsen; Demoly, Pascal; Franklin, Karl Anders; Gallastegui, Leire Sainz de Aja; González, Francisco Javier Callejas; Heinrich, Joachim; Holm, Mathias; Jogi, Nils Oscar; Leynaert, Benedicte; Lindberg, Eva; Malinovschi, Andrei; Martínez-Moratalla, Jesús; Mayoral, Raúl Godoy; Oudin, Anna; Pereira-Vega, Antonio; Semjen, Chantal Raherison; Schlünssen, Vivi; Triebner, Kai; Øksnes, Marianne (2022-05)
    Objective: To investigate markers of premature menopause (<40 years) and specifically the prevalence of autoimmune primary ovarian insufficiency (POI) in European women. Design: Postmenopausal women were categorized according to age at menopause and ...
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    Register-based information on thyroid diseases in Europe : lessons and results from the EUthyroid collaboration 
    Møllehave, Line Tang; Eliasen, Marie Holm; Strēle, Ieva; Linneberg, Allan; Moreno-Reyes, Rodrigo; Ivanova, Ludmila B.; Kusić, Zvonko; Erlund, Iris; Ittermann, Till; Nagy, Endre V.; Gunnarsdóttir, Ingibjörg; Arbelle, Jonathan Eli; Troen, Aaron Milton; Pīrāgs, Valdis; Dahl, Lisbeth; Hubalewska-Dydejczyk, Alicja; Trofimiuk-Müldner, Malgorzata; de Castro, João Jacome; Marcelino, Mafalda; Gaberšček, Simona; Zaltel, Katja; Puig-Domingo, Manuel; Vila, Lluis; Manousou, Sofia; Nyström, Helena Filipsson; Zimmermann, Michael Bruce; Mullan, Karen R.; Woodside, Jayne Valerie; Völzke, Henry; Thuesen, Betina Heinsbæk (2022-03-10)
    Objective: Registers of diagnoses and treatments exist in different forms in the European countries and are potential sources to answer important research questions. Prevalence and incidence of thyroid diseases are highly dependent on iodine intake ...
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    Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours : a consensus statement 
    Boguszewski, Margaret C.S.; Boguszewski, Cesar L.; Chemaililly, Wassim; Cohen, Laurie E.; Gebauer, Judith; Higham, Claire; Hoffman, Andrew R.; Polak, Michel; Yuen, Kevin C.J.; Alos, Nathalie; Antal, Zoltan; Bidlingmaier, Martin; Biller, Beverley M.K.; Brabant, George; Choong, Catherine S.Y.; Cianfarani, Stefano; Clayton, Peter E.; Coutant, Regis; Cardoso-Demartini, Adriane A.; Fernandez, Alberto; Grimberg, Adda; Guðmundsson, Kolbeinn; Guevara-Aguirre, Jaime; K Y Ho, Ken; Horikawa, Reiko; Isidori, Andrea M.; Otto Lunde Jørgensen, Jens; Kamenicky, Peter; Karavitaki, Niki; Kopchick, John J.; Lodish, Maya; Luo, Xiaoping; McCormack, Ann I.; Meacham, Lillian; Melmed, Shlomo; Moab, Sogol Mostoufi; Müller, Hermann L.; Neggers, Sebastian J.C.M.M.; Aguiar Oliveira, Manoel H.; Ozono, Keiichi; Pennisi, Patricia A.; Popovic, Vera; Radovick, Sally; Savendahl, Lars; Touraine, Philippe; van Santen, Hanneke M.; Johannsson, Gudmundur (2022-06)
    Growth hormone (GH) has been used for over 35 years, and its safety and efficacy has been studied extensively. Experimental studies showing the permissive role of GH/insulin-like growth factor 1 (IGF-I) in carcinogenesis have raised concerns regarding ...
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    Serum levels of ACE2 are higher in patients with obesity and diabetes 
    Emilsson, Valur; Guðmundsson, Elías F.; Aspelund, Thor; Jónsson, Brynjólfur G.; Guðjónsson, Alexander; Launer, Lenore J.; Lamb, John R.; Guðmundsdóttir, Valborg; Jennings, Lori L.; Guðnason, Vilmundur G. (2020-12-16)
    Objective: As severity of outcome in COVID-19 is disproportionately higher among individuals with obesity, smokers, patients with hypertension, kidney disease, chronic pulmonary disease, coronary heart disease (CHD), and/or type 2 diabetes (T2D), serum ...
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    Temperature Dependence of Platelet Metabolism 
    Jóhannsson, Freyr; Yurkovich, James T.; Guðmundsson, Steinn; Sigurjónsson, Ólafur Eysteinn; Rolfsson, Óttar (2024-02)
    Temperature plays a fundamental role in biology, influencing cellular function, chemical reaction rates, molecular structures, and interactions. While the temperature dependence of many biochemical reactions is well defined in vitro, the effect of ...
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    Use of Elamipretide in patients assigned treatment in the compassionate use program : Case series in pediatric patients with rare orphan diseases 
    Koenig, Mary Kay; Russo, Sam Nick; McBride, Kim L.; Björnsson, Hans Tómas; Gunnarsdottir, Brynja Bjork; Goldstein, Amy; Falk, Scott A. (2023-01)
    Several mitochondrial diseases are caused by pathogenic variants that impair membrane phospholipid remodeling, with no FDA-approved therapies. Elamipretide targets the inner mitochondrial membrane where it binds to cardiolipin, resulting in improved ...
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    Value of antibodies to GAD65 combined with islet cell cytoplasmic antibodies for predicting IDDM in a childhood population 
    Aanstoot, H. J.; Sigurdsson, Engilbert; Jaffe, M.; Shi, Y.; Christgau, S.; Grobbee, D.; Bruining, G. J.; Molenaar, J. L.; Hofman, A.; Baekkeskov, S. (1994-09)
    The value of a test for islet cell cytoplasmic antibodies together with a test for GAD65 antibodies to predict the subsequent development of diabetes over a period of 11.5 years was assessed in an open childhood population comprising 2,805 individuals. ...
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    Young adults with type 1 diabetes and their experiences with diabetes follow-up and participation in the DiaPROM pilot trial: A qualitative study 
    Hernar, Ingvild; Graue, Marit; Strandberg, Ragnhild B.; Lie, Silje S.; Sigurðardóttir, Árún Kristín; Richards, David A.; Kolltveit, Beate-Christin H.; Haugstvedt, Anne (2021-06)
    Aim To explore young adults' experiences of outpatient follow‐up appointments, completing electronic Patient‐Reported Outcome Measures (PROMs), and using the Problem Areas In Diabetes (PAID) scale during the Diabetes Patient‐Reported Outcome Measures ...