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Browsing by Subject "Developmental Biology"

Browsing by Subject "Developmental Biology"

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    Corrigendum: Electrochemically induced in vitro focal hypoxia in human neurons. : Electrochemically induced in vitro focal hypoxia in human neurons(Front. Cell Dev. Biol., (2022), 10, (968341), 10.3389/fcell.2022.968341) 
    Wong, Joseph J.Y.; Varga, Balazs V.; Káradóttir, Ragnhildur Thóra; Hall, Elizabeth A.H. (2023-01-05)
    In the published article, there was an error in Table 2 as published. This was due to a formatting error during publication causing rows to become misplaced in the final printed copy and subscript information to be lost. The corrected Table 2 and its ...
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    Differential gene expression during early development in recently evolved and sympatric Arctic charr morphs 
    Guðbrandsson, Jóhannes; Franzdottir, Sigridur Rut; Kristjansson, Bjarni K.; Pashay Ahi, Ehsan; Maier, Valerie H.; Kapralova, Kalina; Snorrason, Sigurður S.; Jónsson, Zophonías Oddur; Palsson, Arnar (PeerJ, 2018-02-07)
    Phenotypic differences between closely related taxa or populations can arise through genetic variation or be environmentally induced, leading to altered transcription of genes during development. Comparative developmental studies of closely related ...
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    Electrochemically induced in vitro focal hypoxia in human neurons 
    Wong, Joseph J.Y.; Varga, Balazs V.; Káradóttir, Ragnhildur Thóra; Hall, Elizabeth A.H. (2022-09-28)
    Focalised hypoxia is widely prevalent in diseases such as stroke, cardiac arrest, and dementia. While in some cases hypoxia improves cellular functions, it mostly induces or exacerbates pathological changes. The lack of methodologies that can simulate ...
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    Ethical, legal and social aspects of human cerebral organoids and their governance in Germany, the United Kingdom and the United States 
    Pichl, Anja; Ranisch, Robert; Altinok, Ozan Altan; Antonakaki, Melpomeni; Barnhart, Andrew J.; Bassil, Katherine; Boyd, J. Lomax; Chinaia, Alice Andrea; Diner, Sarah; Gaillard, Maxence; Greely, Henry T.; Jowitt, Joshua; Kreitmair, Karola; Lawrence, David; Lee, Tim Nicholas; McKeown, Alex; Sachdev, Vorathep; Schicktanz, Silke; Sugarman, Jeremy; Trettenbach, Katharina; Wiese, Lara; Wolff, Hannes; Árnason, Garðar (2023-11-13)
    Human cerebral organoids (HCOs) are model systems that enable researchers to investigate the human brain in ways that had previously been impossible. The emergence of HCOs was accompanied by both expert and layperson discussions concerning the possibility ...
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    Fathers' preconception smoking and offspring DNA methylation 
    Kitaba, Negusse Tadesse; Knudsen, Gerd Toril Mørkve; Johannessen, Ane; Rezwan, Faisal I; Malinovschi, Andrei; Oudin, Anna; Benediktsdóttir, Bryndís; Martino, David; González, Francisco Javier Callejas; Gómez, Leopoldo Palacios; Holm, Mathias; Jõgi, Nils Oskar; Dharmage, Shyamali C; Skulstad, Svein Magne; Watkins, Sarah H; Suderman, Matthew; Gómez-Real, Francisco; Schlünssen, Vivi; Svanes, Cecilie; Holloway, John W (2023-08-31)
    Background: Experimental studies suggest that exposures may impact respiratory health across generations via epigenetic changes transmitted specifically through male germ cells. Studies in humans are, however, limited. We aim to identify epigenetic ...
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    Gene expression in the phenotypically plastic Arctic charr (Salvelinus alpinus): A focus on growth and ossification at early stages of development 
    Beck, Samantha V.; Räsänen, Katja; Ahi, Ehsan P.; Kristjánsson, Bjarni K.; Skúlason, Skúli; Jónsson, Zophonías Oddur; Leblanc, Camille (Wiley, 2018-11-26)
    Gene expression during development shapes the phenotypes of individuals. Although embryonic gene expression can have lasting effects on developmental trajectories, few studies consider the role of maternal effects, such as egg size, on gene expression. ...
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    H3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts 
    Pei, Jiayi; Harakalova, Magdalena; Treibel, Thomas A.; Lumbers, R. Thomas; Boukens, Bastiaan J.; Efimov, Igor R.; Van Dinter, Jip T.; González, Arantxa; López, Begoña; El Azzouzi, Hamid; Van Den Dungen, Noortje; Van Dijk, Christian G.M.; Krebber, Merle M.; Den Ruijter, Hester M.; Pasterkamp, Gerard; Duncker, Dirk J.; Nieuwenhuis, Edward E.S.; De Weger, Roel; Huibers, Manon M.; Vink, Aryan; Moore, Jason H.; Moon, James C.; Verhaar, Marianne C.; Kararigas, Georgios; Mokry, Michal; Asselbergs, Folkert W.; Cheng, Caroline (2020-07-14)
    Background: H3K27ac histone acetylome changes contribute to the phenotypic response in heart diseases, particularly in end-stage heart failure. However, such epigenetic alterations have not been systematically investigated in remodeled non-failing human ...
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    MiR-203a is differentially expressed during branching morphogenesis and EMT in breast progenitor cells and is a repressor of peroxidasin 
    Briem, Eiríkur; Budkova, Zuzana; Sigurðardóttir, Anna Karen; Hilmarsdóttir, Bylgja; Kricker, Jennifer; Timp, Winston; Magnusson, Magnus Karl; Traustadottir, Gunnhildur Asta; Gudjonsson, Thorarinn (Elsevier BV, 2019-02)
    MicroRNAs regulate developmental events such as branching morphogenesis, epithelial to mesenchymal transition (EMT) and its reverse process mesenchymal to epithelial transition (MET). In this study, we performed small RNA sequencing of a breast epithelial ...
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    Pentraxins CRP-I and CRP-II are post-translationally deiminated and differ in tissue specificity in cod (Gadus morhua L.) ontogeny 
    Magnadottir, Bergljot; Hayes, Polly; Gísladóttir, Berglind; Bragason, Birkir; Hristova, Mariya; Nicholas, Anthony P.; Guðmundsdóttir, Sigríður; Lange, Sigrun (Elsevier BV, 2018-10)
    Pentraxins arefluid phase pattern recognition molecules that form an important part of the innate immunedefence and are conserved betweenfish and human. In Atlantic cod (Gadus morhuaL.), two pentraxin-likeproteins have been described, CRP-I and CRP-II. ...
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    Peripheral blood DNA methylation and neuroanatomical responses to HDACi treatment that rescues neurological deficits in a Kabuki syndrome mouse model 
    Goodman, Sarah Jessica; Luperchio, Teresa Romeo; Ellegood, Jacob; Chater-Diehl, Eric; Lerch, Jason P.; Björnsson, Hans Tómas; Weksberg, Rosanna (2023-12)
    Background: Recent findings from studies of mouse models of Mendelian disorders of epigenetic machinery strongly support the potential for postnatal therapies to improve neurobehavioral and cognitive deficits. As several of these therapies move into ...
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    Transition of Extremely Preterm Infants from Birth to Stable Breathing : A Secondary Analysis of the CORSAD Trial 
    Dónaldsson, Snorri Freyr; Palleri, Elena; Jonsson, Baldvin; Drevhammar, Thomas (2023-03)
    OBJECTIVE: Exploratory secondary analysis of the CORSAD trial compared a new resuscitation system (rPAP) to the standard T-piece system. This analysis focused on the subgroup of infants who were not intubated in the delivery room. The aim was to compare ...