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Fletta eftir efnisorði "DNA kjarnsýra"

Fletta eftir efnisorði "DNA kjarnsýra"

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    Advancements in site-directed incorporation of rigid spin-labels into nucleic acids 
    Júlíusson, Haraldur Yngvi (University of Iceland, School of Engineering and Natural Sciences, Faculty of Physical Sciences, 2020-02-01)
    Rafeindasegullitrófsgreiningu (e. Electron Paramagnetic Resonance, EPR) er reglubundið beitt í rannsóknum á byggingu og hreyfingu kjarnsýra til að fá upplýsingar um starfsemi þeirra og hlutverk. Innleiðing meðseglandi kjarna á ákveðinn stað í kjarnsýrum ...
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    DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis 
    Kular, Lara; Liu, Yun; Ruhrmann, Sabrina; Zheleznyakova, Galina; Marabita, Francesco; Gomez-Cabrero, David; James, Tojo; Ewing, Ewoud; Lindén, Magdalena; Górnikiewicz, Bartosz; Aeinehband, Shahin; Stridh, Pernilla; Link, Jenny; Andlauer, Till F. M.; Gasperi, Christiane; Wiendl, Heinz; Zipp, Frauke; Gold, Ralf; Tackenberg, Björn; Weber, Frank; Hemmer, Bernhard; Strauch, Konstantin; Heilmann-Heimbach, Stefanie; Rawal, Rajesh; Schminke, Ulf; Schmidt, Carsten O.; Kacprowski, Tim; Franke, Andre; Laudes, Matthias; Dilthey, Alexander T.; Celius, Elisabeth G.; Søndergaard, Helle B.; Tegnér, Jesper; Harbo, Hanne F.; Oturai, Annette B.; Sigurgeir Ólafsson; Eggertsson, Hannes; Halldórsson, Bjarni; Hjaltason, Haukur; Elías Ólafsson; Jonsdottir, Ingileif; Stefansson, Kari; Olsson, Tomas; Piehl, Fredrik; Ekström, Tomas J.; Kockum, Ingrid; Feinberg, Andrew P.; Jagodic, Maja (Springer Science and Business Media LLC, 2018-06-19)
    The human leukocyte antigen (HLA) haplotype DRB1*15:01 is the major risk factor for multiple sclerosis (MS). Here, we find that DRB1*15:01 is hypomethylated and predominantly expressed in monocytes among carriers of DRB1*15:01. A differentially methylated ...
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    Screening and computational analysis of colorectal associated non-synonymous polymorphism in CTNNB1 gene in Pakistani population 
    Razak, Suhail; Bibi, Nousheen; Dar, Javid Ahmad; Afsar, Tayyaba; Almajwal, Ali; Parveen, Zahida; Jahan, Sarwat (Springer Science and Business Media LLC, 2019-11-07)
    Background: Colorectal cancer (CRC) is categorized by alteration of vital pathways such as β-catenin (CTNNB1) mutations, WNT signaling activation, tumor protein 53 (TP53) inactivation, BRAF, Adenomatous polyposis coli (APC) inactivation, KRAS, dysregulation ...
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    Synthesis of DNA and RNA containing rigid spin- and fluorescent labels for studies by EPR and fluorescence spectroscopies 
    Segler, Anna-Lena Johanna (2021-09)
    To gain information about the function of nucleic acids, their structure and dynamics need to be investigated. Electron paramagnetic resonance (EPR)- and fluorescence spectroscopies are highly sensitive and valuable techniques to study nucleic acids. ...
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    TEMPO-derived spin labels linked to the nucleobases adenine and cytosine for probing local structural perturbations in DNA by EPR spectroscopy 
    Gophane, Dnyaneshwar B; Sigurdsson, Snorri (Beilstein Institut, 2015-02-09)
    Three 2´-deoxynucleosides containing semi-flexible spin labels, namely TA, UA and UC, were prepared and incorporated into deoxyoligonucleotides using the phosphoramidite method. All three nucleosides contain 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) ...