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Fletta eftir efnisorði "Coronary artery disease"

Fletta eftir efnisorði "Coronary artery disease"

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    Genetics of coronary atherosclerosis with an emphasis on blood lipids 
    Björnsson, Eyþór (University of Iceland, School of Health Sciences, Faculty of Medicine, 2021-10-08)
    Kransæðasjúkdómur dregur fleiri til dauða á hverju ári en nokkur annar sjúkdómur á heimsvísu. Sjúkdómurinn einkennist af framvindu æðakölkunar, sem er flókið og margþætt ferli. Á undanförnum 14 árum hafa rannsóknir með víðtækri erfðamengisleit leitt ...
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    Lipoprotein(a) Concentration and Risks of Cardiovascular Disease and Diabetes 
    Gudbjartsson, Daniel; Thorgeirsson, Gudmundur; sulem, patrick; Helgadottir, Anna; Gylfason, Arnaldur; Sæmundsdóttir, Jóna; Björnsson, Eyþór; Norðdahl, Guðmundur L.; Jónasdóttir, Áslaug; Jónasdóttir, Aðalbjörg; Eggertsson, Hannes; Grétarsdóttir, Sólveig; Thorleifsson, Gudmar; Indridason, Olafur Skuli; Palsson, Runolfur; Jónasson, Friðbert; Jonsdottir, Ingileif; Eyjólfsson, Guðmundur I.; Sigurðardóttir, Ólöf; Ólafsson, Ísleifur; Danielsen, Ragnar; Matthíasson, Stefán E.; Kristmundsdóttir, Snædís; Halldórsson, Bjarni V.; Hreiðarsson, Ástráður Benedikt; Valdimarsson, Einar M.; Gudnason, Thorarinn; Benediktsson, Rafn; Steinthorsdottir, Valgerdur; Thorsteinsdottir, Unnur; Holm, Hilma; Stefansson, Kari (Elsevier BV, 2019-12-17)
    Background: Lipoprotein(a) [Lp(a)] is a causal risk factor for cardiovascular diseases that has no established therapy. The attribute of Lp(a) that affects cardiovascular risk is not established. Low levels of Lp(a) have been associated with type 2 ...
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    Meðferð sjúklinga með sykursýki og kransæðasjúkdóm á Íslandi: : Víkkun, hjáveituaðgerð eða lyfjameðferð? 
    Kristjansdottir, Margret Kristin; Reynisdottir, Heidrun Osk; Mogensen, Brynjólfur Árni; Andersen, Karl Konráð; Guðbjartsson, Tómas; Sigurðsson, Martin Ingi; Guðmundsdóttir, Ingibjörg Jóna (2022-07-07)
    INNGANGUR Sykursýki er vaxandi vandamál en sykursjúkir eru í aukinni hættu á æðakölkun og útbreiddum kransæðasjúkdómi miðað við annað fólk. Tilgangur rannsóknarinnar var að kanna hvernig meðferð kransæðasjúkdóms sykursjúkra var háttað á Íslandi frá ...
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    NBEAL1 controls SREBP2 processing and cholesterol metabolism and is a susceptibility locus for coronary artery disease 
    Bindesbøll, Christian; Aas, Aleksander; Ogmundsdottir, Margret H; Pankiv, Serhiy; Reine, Trine; Zoncu, Roberto; Simonsen, Anne (Springer Science and Business Media LLC, 2020-03-11)
    Dysregulated cholesterol homeostasis promotes the pathology of atherosclerosis, myocardial infarction and strokes. Cellular cholesterol is mainly regulated at the transcriptional level by SREBP2, but also through uptake of extracellular cholesterol ...
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    A pooled-analysis of age and sex based coronary artery calcium scores percentiles 
    de Ronde, Maurice W.J.; Khoshiwal, Amir; Planken, R. Nils; Boekholdt, S. Matthijs; Biemond, Mariette; Budoff, Matthew J.; Cooil, Bruce; Lotufo, Paulo A.; Bensenor, Isabela M.; Ohmoto-Sekine, Yuki; Gudnason, Vilmundur; Aspelund, Thor; Gudmundsson, Elias Freyr; Zwinderman, Aeilko H.; Raggi, Paolo; Pinto-Sietsma, Sara Joan (2020-09-01)
    Background: Age and sex based coronary artery calcium score (CAC) percentiles have been used to improve coronary artery disease (CAD) risk prediction. However, the main limitation of the CACs percentiles currently in use is that they are often based ...
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    Rare SCARB1 mutations associate with high-density lipoprotein cholesterol but not with coronary artery disease 
    Helgadottir, Anna; sulem, patrick; Thorgeirsson, Gudmundur; Grétarsdóttir, Sólveig; Thorleifsson, Gudmar; Jensson, Brynjar Örn; Arnadottir, Gudny; Olafsson, Isleifur; Eyjólfsson, Guðmundur I.; Sigurdardottir, Olof; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Holm, Hilma; Stefansson, Kari (Oxford University Press (OUP), 2018-03-27)
    Aims Scavenger receptor Class B Type 1 (SR-BI) is a major receptor for high-density lipoprotein (HDL) that promotes hepatic uptake of cholesterol from HDL. A rare mutation p.P376L, in the gene encoding SR-BI, SCARB1, was recently reported to associate ...