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Fletta eftir efnisorði "COVID-19/genetics"

Fletta eftir efnisorði "COVID-19/genetics"

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    HLA alleles, disease severity, and age associate with T-cell responses following infection with SARS-CoV-2 
    Olafsdottir, Thorunn A; Bjarnadottir, Kristbjorg; Norddahl, Gudmundur L.; Halldórsson, Gísli Hreinn; Melsted, Páll; Gunnarsdottir, Kristbjorg; Ivarsdottir, Erna; Olafsdottir, Thorhildur; Arnthorsson, Asgeir O; Theódórs, Fannar; Eyþórsson, Elías Sæbjörn; Helgason, Dadi; Eggertsson, Hannes P.; Masson, Gisli; Bjarnadottir, Solveig; Sævarsdóttir, Sædís; Runólfsdóttir, Hrafnhildur L.; Ólafsson, Ísleifur; Saemundsdottir, Jona; Sigurðsson, Martin Ingi; Ingvarsson, Ragnar Freyr; Pálsson, Runólfur; Thorgeirsson, Gudmundur; Halldórsson, Bjarni Vilhjálmur; Holm, Hilma; Kristjánsson, Már; Sulem, Patrick; Þorsteinsdóttir, Unnur; Jónsdóttir, Ingileif; Gudbjartsson, Daniel F; Stefansson, Kari (2022-09-06)
    Memory T-cell responses following SARS-CoV-2 infection have been extensively investigated but many studies have been small with a limited range of disease severity. Here we analyze SARS-CoV-2 reactive T-cell responses in 768 convalescent SARS-CoV-2-infected ...
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    A proteome-wide genetic investigation identifies several sars-cov-2-exploited host targets of clinical relevance 
    Karim, Mohd A.; Shilts, Jarrod; Schwartzentruber, Jeremy; Hayhurst, James; Buniello, Annalisa; Mohammed, Elmutaz Shaikho Elhaj; Zheng, Jie; Holmes, Michael V.; Ochoa, David; Carmona, Miguel; Maranville, Joseph; Gaunt, Tom R.; Emilsson, Valur; Guðnason, Vilmundur G.; McDonagh, Ellen M.; Wright, Gavin J.; Ghoussaini, Maya; Dunham, Ian (2021-08-17)
    Background: The virus SARS-CoV-2 can exploit biological vulnerabilities (e.g. host proteins) in susceptible hosts that predispose to the development of severe COVID-19. Methods: To identify host proteins that may contribute to the risk of severe COVID-19, ...