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Browsing by Subject "Animals"

Browsing by Subject "Animals"

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  • Hamm, Michael; Sohier, Pierre; Petit, Valérie; Raymond, Jérémy H.; Delmas, Véronique; Le Coz, Madeleine; Gesbert, Franck; Kenny, Colin; Aktary, Zackie; Pouteaux, Marie; Rambow, Florian; Sarasin, Alain; Charoenchon, Nisamanee; Bellacosa, Alfonso; Sanchez-del-Campo, Luis; Mosteo, Laura; Lauss, Martin; Meijer, Dies; Steingrímsson, Eiríkur; Jönsson, Göran B.; Cornell, Robert A.; Davidson, Irwin; Goding, Colin R.; Larue, Lionel (2021-06-17)
    While the major drivers of melanoma initiation, including activation of NRAS/BRAF and loss of PTEN or CDKN2A, have been identified, the role of key transcription factors that impose altered transcriptional states in response to deregulated signaling ...
  • Chartier, Lauren C.; Fujino, Junko; Howarth, Gordon S.; Freysdóttir, Jóna; Harðardóttir, Ingibjörg; Mashtoub, Suzanne (2021-06)
    BACKGROUND: Emu Oil (EO) previously demonstrated therapeutic potential in a mouse model of colitis-associated CRC (CA-CRC). Saireito, a traditional Japanese medicine, has not been investigated in CA-CRC. AIM: To determine whether EO and Saireito could ...
  • Helgadóttir, Helga; Tropea, Teresa; Gizurarson, Sveinbjörn; Mandalà, Maurizio (2021-09-21)
    Acetylsalicylic acid (aspirin) exhibits a broad range of activities, including analgesic, antipyretic, and antiplatelet properties. Recent clinical studies also recommend aspirin prophylaxis in women with a high risk of pre-eclampsia, a major complication ...
  • Ajjampur, Sitara S.R.; Kaliappan, Saravanakumar Puthupalayam; Halliday, Katherine E.; Palanisamy, Gokila; Farzana, Jasmine; Manuel, Malathi; Abraham, Dilip; Laxmanan, Selvi; Aruldas, Kumudha; Rose, Anuradha; Kennedy, David S.; Oswald, William E.; Pullan, Rachel L.; Galagan, Sean R.; Ásbjörnsdóttir, Kristjana Hrönn; Anderson, Roy M.; Muliyil, Jayaprakash; Sarkar, Rajiv; Kang, Gagandeep; Walson, Judd L. (2021-04-30)
    Since 2015, India has coordinated the largest school-based deworming program globally, targeting soil-transmitted helminths (STH) in ~250 million children aged 1 to 19 years twice yearly. Despite substantial progress in reduction of morbidity associated ...
  • Witek-McManus, Stefan; Simwanza, James; Chisambi, Alvin B.; Kepha, Stella; Kamwendo, Zachariah; Mbwinja, Alfred; Samikwa, Lyson; Oswald, William E.; Kennedy, David S.; Timothy, Joseph W.S.; Legge, Hugo; Galagan, Sean R.; Emmanuel-Fabula, Mira; Schaer, Fabian; Ásbjörnsdóttir, Kristjana Hrönn; Halliday, Katherine E.; Walson, Judd L.; Juziwelo, Lazarus; Bailey, Robin L.; Kalua, Khumbo; Pullan, Rachel L. (2021-05-12)
    Malawi has successfully leveraged multiple delivery platforms to scale-up and sustain the implementation of preventive chemotherapy (PCT) for the control of morbidity caused by soil-transmitted helminths (STH). Sentinel monitoring demonstrates this ...
  • Aradottir, Sigridur Sunna; Kristoffersson, Ann Charlotte; Roumenina, Lubka T.; Bjerre, Anna; Kashioulis, Pavlos; Pálsson, Runólfur; Karpman, Diana (2021-06-10)
    Complement factor B (FB) mutant variants are associated with excessive complement activation in kidney diseases such as atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy and membranoproliferative glomerulonephritis (MPGN). Patients with aHUS ...
  • Avokpaho, Euripide F.G.A.; Houngbégnon, Parfait; Accrombessi, Manfred; Atindégla, Eloïc; Yard, Elodie; Means, Arianna Rubin; Kennedy, David S.; Littlewood, D. Timothy J.; Garcia, André; Massougbodji, Achille; Galagan, Sean R.; Walson, Judd L.; Cottrell, Gilles; Ibikounlé, Moudachirou; Ásbjörnsdóttir, Kristjana Hrönn; Luty, Adrian J.F. (2021-08-17)
    Background Despite several years of school-based MDA implementation, STH infections remain an important public health problem in Benin, with a country-wide prevalence of 20% in 2015. The DeWorm3 study is designed to assess the feasibility of using ...
  • Martin, Frida; Svansson, Vilhjálmur; Eydal, Matthías; Oddsdóttir, Charlotta; Ernback, Maja; Persson, Isa; Tydén, Eva (2021-01-25)
    Horses in Iceland have been isolated for more than 1,000 yr but still harbor a similar range of gastrointestinal parasites as do horses across the world. The long isolation of the horses and their parasites presumably means that no resistance genes ...
  • Truscott, James E.; Hardwick, Robert J.; Werkman, Marleen; Saravanakumar, Puthupalayam Kaliappan; Manuel, Malathi; Ajjampur, Sitara S.R.; Ásbjörnsdóttir, Kristjana Hrönn; Khumbo, Kalua; Witek-McManus, Stefan; Simwanza, James; Cottrell, Gilles; Houngbégnon, Parfait; Ibikounlé, Moudachirou; Walson, Judd L.; Anderson, Roy M. (2021-01-20)
    BACKGROUND: The DeWorm3 project is an ongoing cluster-randomised trial assessing the feasibility of interrupting the transmission of soil-transmitted helminths (STH) through mass drug administration (MDA) using study sites in India, Malawi and Benin. ...
  • Adlard, Bryan; Lemire, Mélanie; Bonefeld-Jørgensen, Eva C.; Long, Manhai; Ólafsdóttir, Kristín; Odland, Jon O.; Rautio, Arja; Myllynen, Päivi; Sandanger, Torkjel M.; Dudarev, Alexey A.; Bergdahl, Ingvar A.; Wennberg, Maria; Berner, James; Ayotte, Pierre (2021)
    Exposure to mercury (Hg) is a global concern, particularly among Arctic populations that rely on the consumption of marine mammals and fish which are the main route of Hg exposure for Arctic populations.The MercuNorth project was created to establish ...
  • Tribble, James R.; Otmani, Amin; Sun, Shanshan; Ellis, Sevannah A.; Cimaglia, Gloria; Vohra, Rupali; Jöe, Melissa; Lardner, Emma; Venkataraman, Abinaya P.; Domínguez-Vicent, Alberto; Kokkali, Eirini; Rho, Seungsoo; Jóhannesson, Gauti; Burgess, Robert W.; Fuerst, Peter G.; Brautaset, Rune; Kolko, Miriam; Morgan, James E.; Crowston, Jonathan G.; Votruba, Marcela; Williams, Pete A. (2021-07)
    Nicotinamide adenine dinucleotide (NAD) is a REDOX cofactor and metabolite essential for neuronal survival. Glaucoma is a common neurodegenerative disease in which neuronal levels of NAD decline. We assess the effects of nicotinamide (a precursor to ...
  • Thornton, Ian M.; Tagu, Jérôme; Zdravković, Sunčica; Kristjánsson, Árni (2021-05-06)
    Attention is known to play an important role in shaping the behaviour of both human and animal foragers. Here, in three experiments, we built on previous interactive tasks to create an online foraging game for studying divided attention in human ...
  • Leifsson, Rúnar (University of Iceland, School of Humanities, Faculty of History and Philosophy, 2018-05)
    In this thesis the ritual killing and burial of animals on grave-fields in Viking Age Iceland is critically re-evaluated, on a site-by-site basis, in order to characterize these customs and place them in a social and historical context. The foundation ...
  • Dillard, Pierre; Köksal, Hakan; Maggadóttir, Sólrún Melkorka; Winge-Main, Anna; Pollmann, Sylvie; Menard, Mathilde; Myhre, Marit Renée; Mælandsmo, Gunhild M.; Flørenes, Vivi Ann; Gaudernack, Gustav; Kvalheim, Gunnar; Wälchli, Sébastien; Inderberg, Else Marit (2021-03-03)
    T cell receptor (TCR)-engineered T cell therapy is a promising cancer treatment approach. Human telomerase reverse transcriptase (hTERT) is overexpressed in the majority of tumors and a potential target for adoptive cell therapy. We isolated a novel ...