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Browsing by Subject "Animals"

Browsing by Subject "Animals"

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  • Memarian, Parastoo; Pishavar, Elham; Zanotti, Federica; Trentini, Martina; Camponogara, Francesca; Soliani, Elisa; Gargiulo, Paolo; Isola, Maurizio; Zavan, Barbara (2022-01-18)
    The successful clinical application of bone tissue engineering requires customized implants based on the receiver’s bone anatomy and defect characteristics. Three-dimensional (3D) printing in small animal orthopedics has recently emerged as a valuable ...
  • Hamm, Michael; Sohier, Pierre; Petit, Valérie; Raymond, Jérémy H.; Delmas, Véronique; Le Coz, Madeleine; Gesbert, Franck; Kenny, Colin; Aktary, Zackie; Pouteaux, Marie; Rambow, Florian; Sarasin, Alain; Charoenchon, Nisamanee; Bellacosa, Alfonso; Sanchez-del-Campo, Luis; Mosteo, Laura; Lauss, Martin; Meijer, Dies; Steingrímsson, Eiríkur; Jönsson, Göran B.; Cornell, Robert A.; Davidson, Irwin; Goding, Colin R.; Larue, Lionel (2021-06-17)
    While the major drivers of melanoma initiation, including activation of NRAS/BRAF and loss of PTEN or CDKN2A, have been identified, the role of key transcription factors that impose altered transcriptional states in response to deregulated signaling ...
  • Aradottir Pind, Audur Anna; Thorsdottir, Sigrun; Magnusdottir, Gudbjorg Julia; Meinke, Andreas; Del Giudice, Giuseppe; Jonsdottir, Ingileif; Bjarnarson, Stefania P. (2022-08-03)
    The neonatal immune system is distinct from the immune system of older individuals rendering neonates vulnerable to infections and poor responders to vaccination. Adjuvants can be used as tools to enhance immune responses to co-administered antigens. ...
  • Chartier, Lauren C.; Fujino, Junko; Howarth, Gordon S.; Freysdóttir, Jóna; Harðardóttir, Ingibjörg; Mashtoub, Suzanne (2021-06)
    BACKGROUND: Emu Oil (EO) previously demonstrated therapeutic potential in a mouse model of colitis-associated CRC (CA-CRC). Saireito, a traditional Japanese medicine, has not been investigated in CA-CRC. AIM: To determine whether EO and Saireito could ...
  • Helgadóttir, Helga; Tropea, Teresa; Gizurarson, Sveinbjörn; Mandalà, Maurizio (2021-09-21)
    Acetylsalicylic acid (aspirin) exhibits a broad range of activities, including analgesic, antipyretic, and antiplatelet properties. Recent clinical studies also recommend aspirin prophylaxis in women with a high risk of pre-eclampsia, a major complication ...
  • Tzachor, Asaf; Smidt-Jensen, Asger; Ramel, Alfons; Geirsdóttir, Margrét (2022-09-07)
    Spirulina algae (Spirulina platensis) cultivated in geothermally powered photobioreactors is here proposed as a potentially resource efficient, zero-carbon, and nutritious alternative to conventional beef meat. Employing a standard life cycle assessment, ...
  • Ajjampur, Sitara S.R.; Kaliappan, Saravanakumar Puthupalayam; Halliday, Katherine E.; Palanisamy, Gokila; Farzana, Jasmine; Manuel, Malathi; Abraham, Dilip; Laxmanan, Selvi; Aruldas, Kumudha; Rose, Anuradha; Kennedy, David S.; Oswald, William E.; Pullan, Rachel L.; Galagan, Sean R.; Ásbjörnsdóttir, Kristjana Hrönn; Anderson, Roy M.; Muliyil, Jayaprakash; Sarkar, Rajiv; Kang, Gagandeep; Walson, Judd L. (2021-04-30)
    Since 2015, India has coordinated the largest school-based deworming program globally, targeting soil-transmitted helminths (STH) in ~250 million children aged 1 to 19 years twice yearly. Despite substantial progress in reduction of morbidity associated ...
  • Witek-McManus, Stefan; Simwanza, James; Chisambi, Alvin B.; Kepha, Stella; Kamwendo, Zachariah; Mbwinja, Alfred; Samikwa, Lyson; Oswald, William E.; Kennedy, David S.; Timothy, Joseph W.S.; Legge, Hugo; Galagan, Sean R.; Emmanuel-Fabula, Mira; Schaer, Fabian; Ásbjörnsdóttir, Kristjana Hrönn; Halliday, Katherine E.; Walson, Judd L.; Juziwelo, Lazarus; Bailey, Robin L.; Kalua, Khumbo; Pullan, Rachel L. (2021-05-12)
    Malawi has successfully leveraged multiple delivery platforms to scale-up and sustain the implementation of preventive chemotherapy (PCT) for the control of morbidity caused by soil-transmitted helminths (STH). Sentinel monitoring demonstrates this ...
  • Aradottir, Sigridur Sunna; Kristoffersson, Ann Charlotte; Roumenina, Lubka T.; Bjerre, Anna; Kashioulis, Pavlos; Pálsson, Runólfur; Karpman, Diana (2021-06-10)
    Complement factor B (FB) mutant variants are associated with excessive complement activation in kidney diseases such as atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy and membranoproliferative glomerulonephritis (MPGN). Patients with aHUS ...
  • Avokpaho, Euripide F.G.A.; Houngbégnon, Parfait; Accrombessi, Manfred; Atindégla, Eloïc; Yard, Elodie; Means, Arianna Rubin; Kennedy, David S.; Littlewood, D. Timothy J.; Garcia, André; Massougbodji, Achille; Galagan, Sean R.; Walson, Judd L.; Cottrell, Gilles; Ibikounlé, Moudachirou; Ásbjörnsdóttir, Kristjana Hrönn; Luty, Adrian J.F. (2021-08-17)
    Background Despite several years of school-based MDA implementation, STH infections remain an important public health problem in Benin, with a country-wide prevalence of 20% in 2015. The DeWorm3 study is designed to assess the feasibility of using ...
  • Martin, Frida; Svansson, Vilhjálmur; Eydal, Matthías; Oddsdóttir, Charlotta; Ernback, Maja; Persson, Isa; Tydén, Eva (2021-01-25)
    Horses in Iceland have been isolated for more than 1,000 yr but still harbor a similar range of gastrointestinal parasites as do horses across the world. The long isolation of the horses and their parasites presumably means that no resistance genes ...
  • Truscott, James E.; Hardwick, Robert J.; Werkman, Marleen; Saravanakumar, Puthupalayam Kaliappan; Manuel, Malathi; Ajjampur, Sitara S.R.; Ásbjörnsdóttir, Kristjana Hrönn; Khumbo, Kalua; Witek-McManus, Stefan; Simwanza, James; Cottrell, Gilles; Houngbégnon, Parfait; Ibikounlé, Moudachirou; Walson, Judd L.; Anderson, Roy M. (2021-01-20)
    BACKGROUND: The DeWorm3 project is an ongoing cluster-randomised trial assessing the feasibility of interrupting the transmission of soil-transmitted helminths (STH) through mass drug administration (MDA) using study sites in India, Malawi and Benin. ...
  • Mishra, Aniket; Duplaà, Cecile; Vojinovic, Dina; Suzuki, Hideaki; Sargurupremraj, Muralidharan; Zilhão, Nuno R.; Li, Shuo; Bartz, Traci M.; Jian, Xueqiu; Zhao, Wei; Hofer, Edith; Wittfeld, Katharina; Harris, Sarah E.; Van Der Auwera-Palitschka, Sandra; Luciano, Michelle; Bis, Joshua C.; Adams, Hieab H.H.; Satizabal, Claudia L.; Gottesman, Rebecca F.; Gampawar, Piyush G.; Bülow, Robin; Weiss, Stefan; Yu, Miao; Bastin, Mark E.; Lopez, Oscar L.; Vernooij, Meike W.; Beiser, Alexa S.; Völker, Uwe; Kacprowski, Tim; Soumare, Aicha; Smith, Jennifer A.; Knopman, David S.; Morris, Zoe; Zhu, Yicheng; Rotter, Jerome I.; Dufouil, Carole; Valdes Hernández, Maria; Muñoz Maniega, Susana; Lathrop, Mark; Boerwinkle, Erik; Schmidt, Reinhold; Ihara, Masafumi; Mazoyer, Bernard; Yang, Qiong; Joutel, Anne; Tournier-Lasserve, Elizabeth; Launer, Lenore J.; Deary, Ian J.; Mosley, Thomas H.; Gudnason, Vilmundur (2022-06-01)
    Cerebral small vessel disease is a leading cause of stroke and a major contributor to cognitive decline and dementia, but our understanding of specific genes underlying the cause of sporadic cerebral small vessel disease is limited. We report a genome-wide ...
  • Global Dietary Database (2022-03)
    Background: Diet is a major modifiable risk factor for human health and overall consumption patterns affect planetary health. We aimed to quantify global, regional, and national consumption levels of animal-source foods (ASF) to inform intervention, ...
  • Grinde, Maria T; Hilmarsdóttir, Bylgja; Tunset, Hanna Maja; Henriksen, Ida Marie; Kim, Jana; Haugen, Mads H; Rye, Morten Beck; Mælandsmo, Gunhild M; Moestue, Siver A (2019-05-14)
    INTRODUCTION: Glutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione. The drug CB-839 has shown promising effects ...
  • Gislason, David; Asmundsson, Tryggvi; Gíslason, Þórarinn (2021-03)
    Ágrip Sjúkdómar tengdir vinnu í heyryki hafa lengi verið þekktir á Íslandi. Árið 1981 hófust rannsóknir á heysjúkdómum að beiðni bændasamtakanna og eru helstu niðurstöður þeirra dregnar saman í þessari grein. Í ljós kom að mikið magn af heymítlum, myglu ...
  • Adlard, Bryan; Lemire, Mélanie; Bonefeld-Jørgensen, Eva C.; Long, Manhai; Ólafsdóttir, Kristín; Odland, Jon O.; Rautio, Arja; Myllynen, Päivi; Sandanger, Torkjel M.; Dudarev, Alexey A.; Bergdahl, Ingvar A.; Wennberg, Maria; Berner, James; Ayotte, Pierre (2021)
    Exposure to mercury (Hg) is a global concern, particularly among Arctic populations that rely on the consumption of marine mammals and fish which are the main route of Hg exposure for Arctic populations.The MercuNorth project was created to establish ...
  • Reynisdottir, Tinna; Anderson, Kimberley Jade; Boukas, Leandros; Bjornsson, Hans Tomas (2022-06-21)
    Wiedemann-Steiner syndrome (WDSTS) is a neurodevelopmental disorder caused by de novo variants in KMT2A, which encodes a multi-domain histone methyltransferase. To gain insight into the currently unknown pathogenesis of WDSTS, we examined the spatial ...
  • Tryggvadottir, Ellen A; Halldorsson, Thorhallur I; Birgisdottir, Bryndis E; Hrolfsdottir, Laufey; Landberg, Rikard; Hreidarsdottir, Ingibjorg Th; Hardardottir, Hildur; Gunnarsdottir, Ingibjorg (2022-05-06)
    TILGANGUR Fyrri rannsóknir benda til að hluti barnshafandi kvenna á Íslandi uppfylli ekki ráðlögð viðmið fyrir neyslu langra ómega-3 fitusýra, sem eru taldar mikilvægar fyrir fósturþroska. Markmið rannsóknarinnar var að meta neyslutíðni barnshafandi ...
  • Tribble, James R.; Otmani, Amin; Sun, Shanshan; Ellis, Sevannah A.; Cimaglia, Gloria; Vohra, Rupali; Jöe, Melissa; Lardner, Emma; Venkataraman, Abinaya P.; Domínguez-Vicent, Alberto; Kokkali, Eirini; Rho, Seungsoo; Jóhannesson, Gauti; Burgess, Robert W.; Fuerst, Peter G.; Brautaset, Rune; Kolko, Miriam; Morgan, James E.; Crowston, Jonathan G.; Votruba, Marcela; Williams, Pete A. (2021-07)
    Nicotinamide adenine dinucleotide (NAD) is a REDOX cofactor and metabolite essential for neuronal survival. Glaucoma is a common neurodegenerative disease in which neuronal levels of NAD decline. We assess the effects of nicotinamide (a precursor to ...