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Fletta eftir efnisorði "Aging"

Fletta eftir efnisorði "Aging"

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    Advancing clinical evaluation and diagnostics with artificial intelligence technologies 
    Recenti, Marco (2023-03)
    Machine Learning (ML) is extensively used in diverse healthcare applications to aid physicians in diagnosing and identifying associations, sometimes hidden, between dif- ferent biomedical parameters. This PhD thesis investigates the interplay of ...
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    Age, Sex, Body Mass Index, Diet and Menopause Related Metabolites in a Large Homogeneous Alpine Cohort 
    Hernandes, Vinicius Verri; Dordevic, Nikola; Hantikainen, Essi Marjatta; Sigurðsson, Baldur Bragi; Smárason, Sigurður Vidir; Garcia-Larsen, Vanessa; Gögele, Martin; Caprioli, Giulia; Bozzolan, Ilaria; Pramstaller, Peter P.; Rainer, Johannes (2022-02-24)
    Metabolomics in human serum samples provide a snapshot of the current metabolic state of an individuum. Metabolite concentrations are influenced by both genetic and environmental factors. Concentrations of certain metabolites can further depend on age, ...
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    Associations of plasma NfL, GFAP, and t-tau with cerebral small vessel disease and incident dementia : longitudinal data of the AGES-Reykjavik Study 
    van Gennip, April C.E.; Satizabal, Claudia L.; Tracy, Russell P.; Sigurdsson, Sigurdur; Gudnason, Vilmundur; Launer, Lenore J.; van Sloten, Thomas T. (2023-08-02)
    We investigated the associations of plasma neurofilament light (NfL), glial fibrillary acidic protein (GFAP), and total tau (t-tau) with markers of cerebral small vessel disease (SVD) and with incident dementia. We also investigated whether associations ...
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    Cognition and brain health among older adults in Iceland : the AGES-Reykjavik study 
    Valsdóttir, Vaka; Magnúsdóttir, Brynja Björk; Chang, Milan; Sigurdsson, Sigurdur; Guðnason, Vilmundur G; Launer, Lenore J.; Jónsdóttir, María Kristín (2022-12)
    The paper aimed to compare how factors previously identified as predictive factors for cognitive decline and dementia related to cognitive performance on the one hand and brain health on the other. To that aim, multiple linear regression was applied ...
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    Comparative study of machine learning methods for modeling associations between risk factors and future dementia cases 
    Valsdóttir, Vaka; Jónsdóttir, María Kristín; Magnúsdóttir, Brynja Björk; Chang, Milan; Hu, Yi Han; Gudnason, Vilmundur; Launer, Lenore J.; Stefánsson, Hlynur (2024-02)
    A substantial portion of dementia risk can be attributed to modifiable risk factors that can be affected by lifestyle changes. Identifying the contributors to dementia risk could prove valuable. Recently, machine learning methods have been increasingly ...
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    Comparison of summer and winter objectively measured physical activity and sedentary behavior in older adults: Age, gene/environment susceptibility Reykjavik study 
    Arnardóttir, Nanna Ýr; Óskarsdóttir, Nína Dóra; Brychta, Robert J.; Koster, Annemarie; van Domelen, Dane R.; Caserotti, Paolo; Eiriksdottir, Gudny; Sverrisdóttir, Jóhanna E.; Jóhannsson, Erlingur; Launer, Lenore J.; Gudnason, Vilmundur; Harris, Tamara B.; Chen, Kong Y.; Sveinsson, Thorarinn (MDPI AG, 2017-10-21)
    In Iceland, there is a large variation in daylight between summer and winter. The aim of the study was to identify how this large variation influences physical activity (PA) and sedentary behavior (SB). Free living PA was measured by a waist-worn ...
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    Comparison of summer and winter objectively measured physical activity and sedentary behavior in older adults: Age, gene/environment susceptibility Reykjavik study 
    Arnardóttir, Nanna Ýr; Oskarsdottir, Nina Dora; Brychta, Robert J.; Koster, Annemarie; Van Domelen, Dane R.; Caserotti, Paolo; Eiriksdottir, Gudny; Sverrisdottir, Johanna E.; Johannsson, Erlingur; Launer, Lenore J.; Guðnason, Vilmundur G; Harris, Tamara B.; Chen, Kong Y.; Sveinsson, Þórarinn (2017-10-21)
    In Iceland, there is a large variation in daylight between summer and winter. The aim of the study was to identify how this large variation influences physical activity (PA) and sedentary behavior (SB). Free living PA was measured by a waist-worn ...
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    Describing the status of reproductive ageing simply and precisely: A reproductive ageing score based on three questions and validated with hormone levels 
    Triebner, Kai; Johannessen, Ane; Svanes, Cecilie; Leynaert, Bénédicte; Benediktsdóttir, Bryndís; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Heinrich, Joachim; Holm, Mathias; Jarvis, Deborah; Lindberg, Eva; Rovira, Jesús Martínez Moratalla; Muniozguren Agirre, Nerea; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Skulstad, Svein Magne; Hustad, Steinar; Rodriguez, Francisco J.; Gómez Real, Francisco (Public Library of Science (PLoS), 2020-06-30)
    Objective: Most women live to experience menopause and will spend 4–8 years transitioning from fertile age to full menstrual stop. Biologically, reproductive ageing is a continuous process, but by convention, it is defined categorically as pre-, peri- ...
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    Determinants of physical function in community dwelling old people 
    Geirsdottir, Olöf G.; Chang, Milan; Briem, Kristin; Jonsson, Pálmi V.; Thorsdottir, Inga; Ramel, Alfonso (2022-03)
    Background. Poor physical function is associated with disability and mortality in old people. Objectives. The aim was to find determinants of physical function in old people. Design. Secondary, cross-sectional analysis. Setting. Community in the ...
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    Icelandic stroke survivors: Functioning and contextual factors and ActivABLES for home-based exercise and physical activity 
    Olafsdottir, Steinunn A (University of Iceland, School of Health Sciences, Faculty of Medicine, 2021-06)
    Aims: The aims of this thesis were: (1) to describe functioning and contextual factors of community-dwelling stroke survivors 1-2 years after their first stroke, based on the International Classification of Functioning, Disability and Health (ICF) ...
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    The importance of different frailty domains in a population based sample in England 
    Arnadottir, Solveig A.; Bruce, Julie; Lall, Ranjit; Withers, Emma J.; Underwood, Martin; Shaw, Fiona; Sheridan, Ray; Hossain, Anower; Lamb, Sarah E.; Martin, Finbarr; Yardley, Lucy; Skelton, Dawn; Willett, Keith; Eldridge, Sandra; Slowther, Anne Marie; Duggan, Sarah; Bruce, Julie; Hennings, Susie; Withers, Emma; Mant, Rhys; Rai, Rishpal; Turner, Craig; Andrews, Agata; Fearn, Rachael; Finnegan, Susanne; Walker, Nicola; Potter, Rachel; Lall, Ranjit; Hulme, Claire; Bojke, Chris; Longo, Roberta; Finnegan, Susanne; Westacott, Katherine; Ralhan, Shvaita; Sheridan, Ray; Treml, Jonathan; Sheridan, Ray; Riglin, Jackie; Gordjin, Harm; Dutta, Ruma; Burns, Jo; Treml, Jonathan; Shaw, Fiona; Davison, John; Willis, Ade; Muthiah, Chocks; Adjei, Henry (2020-01-15)
    Background: The aim was to estimate the prevalence of frailty and relative contribution of physical/balance, nutritive, cognitive and sensory frailty to important adverse health states (falls, physical activity levels, outdoor mobility, problems in ...
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    Influence of day length and physical activity on sleep patterns in older Icelandic men and women 
    Brychta, Robert J.; Arnardottir, Nanna Yr; Johannsson, Erlingur; Wright, Elizabeth C.; Eiriksdottir, Gudny; Gudnason, Vilmundur; Marinac, Catherine R.; Davis, Megan; Koster, Annemarie; Caserotti, Paolo; Sveinsson, Thorarinn; Harris, Tamara; Chen, Kong Y. (2016-02-15)
    Study Objectives: To identify cross-sectional and seasonal patterns of sleep and physical activity (PA) in community-dwelling, older Icelandic adults using accelerometers. Methods: A seven-day free-living protocol of 244 (110 female) adults aged 79.7 ...
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    A Non-linear Relationship Between Selective Attention and Associated ERP Markers Across the Lifespan 
    Reuter, Eva-Maria; Vieluf, Solveig; Koutsandreou, Flora; Hübner, Lena; Budde, Henning; Godde, Ben; Voelcker-Rehage, Claudia (Frontiers Media SA, 2019-01-28)
    The ability to selectively attend to task-relevant information increases throughout childhood and decreases in older age. Here, we intended to investigate these opposing developmental trajectories, to assess whether gains and losses early and late in ...
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    Phenotypic Displays of Cholinergic Enzymes Associate With Markers of Inflammation, Neurofibrillary Tangles, and Neurodegeneration in Pre- and Early Symptomatic Dementia Subjects 
    Teitsdottir, U.D.; Darreh-Shori, T.; Lund, S.H.; Jonsdottir, M.K.; Snaedal, J.; Petersen, P.H. (2022-05-26)
    Background: Cholinergic drugs are the most commonly used drugs for the treatment of Alzheimer's disease (AD). Therefore, a better understanding of the cholinergic system and its relation to both AD-related biomarkers and cognitive functions is of high ...
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    Resilience among older adults living at home : Urban-rural difference in a population-based study 
    Sigurðardóttir, Árún Kristín; Steingrimsson, Jon A.; Kristófersson, Gísli Kort; Gunnarsdóttir, Elín Díanna (2022-12)
    Objective. We examined how individual and contextual factors affect resilience in community-dwelling older adults living in urban or rural areas in Northern Iceland. Methods. A cross-sectional study, conducted from 2017–2018, ran-domly sampled ...
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    Serum lipids in adults with late age-related macular degeneration: a case-control study 
    Semba, Richard; Moaddel, Ruin; Cotch, Mary Frances; Jonasson, Fridbert; Eiriksdottir, Gudny; Harris, Tamara B.; Launer, Lenore J.; Sun, Kai; Klein, Ronald; Schaumberg, Debra Ann; Jónsson, Pálmi V.; Gudnason, Vilmundur; Ferrucci, Luigi (Springer Science and Business Media LLC, 2019-01-08)
    Background: Lipids are implicated in the pathogenesis of age-related macular degeneration (AMD). The relationship between systemic lipids and AMD has not been well characterized. The objective was to investigate the relationship between serum lipids ...