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Fletta eftir sviði "Heilbrigðisvísindasvið (HÍ)"
Atriði 1-20 af 635
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(Informa UK Limited, 2018-01-02) -
(Springer Nature, 2017-04-28)HapMap imputed genome-wide association studies (GWAS) have revealed >50 loci at which common variants with minor allele frequency >5% are associated with kidney function. GWAS using more complete reference sets for imputation, such as those from The ...
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(Springer Nature, 2017-04-25)Several copy number variants have been associated with neuropsychiatric disorders and these variants have been shown to also influence cognitive abilities in carriers unaffected by psychiatric disorders. Previously, we associated the 15q11.2(BP1–BP2) ...
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2-Hydroxypropyl-β-Cyclodextrin Aggregates: Identification and Development of Analytical Techniques (MDPI AG, 2018-10-13)It is extremely important for pharmaceutical formulators to have analytical methodology that provides efficient detection and quantification of HPβCD aggregates. Five different methods were then evaluated for their potential to detect these aggregates ...
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(Springer Science and Business Media LLC, 2019-12-16)Background: Recently we proposed an evolutionary explanation for a spinal pathology that afflicts many people, intervertebral disc herniation (Plomp et al. [2015] BMC Evolutionary Biology 15, 68). Using 2D data, we found that the bodies and pedicles ...
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(MDPI AG, 2018-11-08)An UPLC-qTOF-MS-based dereplication study led to the targeted isolation of seven bromoindole alkaloids from the sub-Arctic sponge Geodia barretti. This includes three new metabolites, namely geobarrettin A–C (1–3) and four known compounds, barettin ...
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(Informa UK Limited, 2019-01-02)Purpose: All types of surgery are associated with complications. The debate is ongoing whether robot-assisted radical prostatectomy can lower this risk compared to open surgery. The objective of the present study was to evaluate post-operative adverse ...
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ABO blood group does not impact incidence or outcomes of surgery for acute type A aortic dissection (Informa UK Limited, 2019-10-23)Objectives. To evaluate the distribution and impact of ABO blood groups on postoperative outcomes in patients undergoing surgery for acute type A aortic dissection (ATAAD). Design. A total of 1144 surgical ATAAD patients from eight Nordic centres ...
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(BMJ, 2020-05-20)Objectives The aim was to study mortality due to suicide, accidental poisoning, event of undetermined intent and drug-related deaths through 20 years in Iceland. Design A population-based register study. Participants Individuals who died due to road ...
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(Springer Science and Business Media LLC, 2018-11-20)Background: A minority of European countries have participated in international comparisons with high level data on lung cancer. However, the nature and extent of data collection across the continent is simply unknown, and without accurate data ...
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(Dove Medical Press Ltd., 2017-08)Xerostomia affects 30% of the population and manifests as a side effect of medications, systemic diseases, or cancer therapy. Oral moisturizers are prescribed to overcome the ailments of dry mouth and its symptoms. It is imperative that these products ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-06)Acute kidney injury (AKI) is a growing problem worldwide and is associated with high morbidity and mortality. AKI is a known complication following cardiac operations and coronary angiography (CA). Following CA, AKI has been associated with contrast ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2017-01-06)In line with advances in surgery, perioperative care, and intensive care, the outcome in patients treated for cardiovascular disease has improved. Open-heart surgery is common in most western countries and, in line with the general ageing of populations, ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-12)Acute kidney injury (AKI) is a common clinical problem both in the hospital and outpatient setting and is associated with increased morbidity and mortality. Chronic kidney disease (CKD) is a risk factor for developing AKI and AKI is a risk factor for ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2020-08-21)Adenine phosphoribosyltransferase (APRT) deficiency is a rare autosomal recessive disorder of adenine metabolism that results in the generation and renal excretion of large amounts of the poorly soluble 2,8-dihydroxyadenine (DHA), causing kidney ...
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(Frontiers Media SA, 2019-09-26)Immaturity of the immune system contributes to poor vaccine responses in early life. Germinal center (GC) activation is limited due to poorly developed follicular dendritic cells (FDC), causing generation of few antibody-secreting cells (ASCs) with ...
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(Public Library of Science (PLoS), 2018-03-07)Sarcopenic muscular degeneration has been consistently identified as an independent risk factor for mortality in aging populations. Recent investigations have realized the quantitative potential of computed tomography (CT) image analysis to describe ...
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(Wiley, 2019-07-08)The current/traditional human health risk assessment paradigm is challenged by recent scientific and technical advances, and ethical demands. The current approach is considered too resource intensive, is not always reliable, can raise issues of ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2018-04-10)Background: Schizophrenia is a chronic serious mental disorder with prevalence close to 0.7%. Early symptoms of schizophrenia generally appear in late adolescence or the early twenties. The prognosis is usually worse in cases of early onset. The ...
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(Wiley, 2020-05-10)Background and purpose: Clinical decision making is facilitated by healthcare professionals’ and patients’ adequate knowledge of the adverse events. This is especially important for biologicals used for treating multiple sclerosis (MS). So far, little ...
Atriði 1-20 af 635