Opin vísindi

Browsing by School "Heilbrigðisvísindasvið (HÍ)"

Browsing by School "Heilbrigðisvísindasvið (HÍ)"

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  • Sigurðsson, Emil Lárus (Informa UK Limited, 2018-01-02)
  • Gorski, Mathias; van der Most, Peter J.; Teumer, Alexander; Chu, Audrey Y.; Li, Man; Mijatovic, Vladan; Nolte, Ilja M.; Cocca, Massimiliano; Taliun, Daniel; Gomez, Felicia; Li, Yong; Tayo, Bamidele; Tin, Adrienne; Feitosa, Mary F.; Aspelund, Thor; Attia, John; Biffar, Reiner; Bochud, Murielle; Boerwinkle, Eric; Borecki, Ingrid; Bottinger, Erwin P.; Chen, Ming-Huei; Chouraki, Vincent; Ciullo, Marina; Coresh, Josef; Cornelis, Marilyn C.; Curhan, Gary C.; d’Adamo, Adamo Pio; Dehghan, Abbas; Dengler, Laura; Ding, Jingzhong; Eiríksdóttir, Guðný; Endlich, Karlhans; Enroth, Stefan; Esko, Tõnu; Franco, Oscar H.; Gasparini, Paolo; Gieger, Christian; Girotto, Giorgia; Gottesman, Omri; Gudnason, Vilmundur; Gyllensten, Ulf; Hancock, Stephen J.; Harris, Tamara B.; Helmer, Catherine; Höllerer, Simon; Hofer, Edith; Hofman, Albert; Holliday, Elizabeth G.; Homuth, Georg; Hu, Frank B.; Huth, Cornelia; Hutri-Kähönen, Nina; Hwang, Shih-Jen; Imboden, Medea; Johansson, Åsa; Kähönen, Mika; König, Wolfgang; Kramer, Holly; Krämer, Bernhard K.; Kumar, Ashish; Kutalik, Zoltán; Lambert, Jean-Charles; Launer, Lenore J.; Lehtimäki, Terho; de Borst, Martin; Navis, Gerjan; Swertz, Morris; Liu, Yongmei; Lohman, Kurt; Loos, Ruth J. F.; Lu, Yingchang; Lyytikäinen, Leo-Pekka; McEvoy, Mark A.; Meisinger, Christa; Meitinger, Thomas; Metspalu, Andres; Metzger, Marie; Mihailov, Evelin; Mitchell, Paul; Nauck, Matthias; Oldehinkel, Albertine J.; Olden, Matthias; WJH Penninx, Brenda; Pistis, Giorgio; Pramstaller, Peter P.; Probst-Hensch, Nicole; Raitakari, Olli T.; Rettig, Rainer; Ridker, Paul M.; Rivadeneira, Fernando; Robino, Antonietta; Rosas, Sylvia E.; Ruderfer, Douglas; Ruggiero, Daniela; Saba, Yasaman; Sala, Cinzia; Schmidt, Helena; Schmidt, Reinhold; Scott, Rodney J.; Sedaghat, Sanaz; Smith, Albert Vernon; Sorice, Rossella; Stengel, Benedicte; Stracke, Sylvia; Strauch, Konstantin; Toniolo, Daniela; Uitterlinden, André G.; Ulivi, Sheila; Viikari, Jorma S.; Völker, Uwe; Vollenweider, Peter; Völzke, Henry; Vuckovic, Dragana; Waldenberger, Melanie; Jin Wang, Jie; Yang, Qiong; Chasman, Daniel I.; Tromp, Gerard; Snieder, Harold; Heid, Iris M.; Fox, Caroline S.; Köttgen, Anna; Pattaro, Cristian; Böger, Carsten A.; Fuchsberger, Christian (Springer Nature, 2017-04-28)
    HapMap imputed genome-wide association studies (GWAS) have revealed >50 loci at which common variants with minor allele frequency >5% are associated with kidney function. GWAS using more complete reference sets for imputation, such as those from The ...
  • Ulfarsson, Magnus; Walters, G B; Gústafsson, O; Steinberg, S; Silva, A; Doyle, O M; Brammer, M; Gudbjartsson, Daniel; Arnarsdóttir, S; Jonsdottir, Gudbjorg; Gísladóttir, R S; Bjornsdottir, Gyda; Helgason, H; Ellingsen, L M; Halldórsson, J G; Sæmundsen, Evald E.; Stefánsdóttir, B; Jónsson, L; Eiríksdóttir, V K; Eiríksdóttir, G R; Jóhannesdóttir, G H; Unnsteinsdóttir, U; Jónsdóttir, B; Magnúsdóttir, B B; sulem, patrick; Þorsteinsdóttir, Unnur; Sigurðsson, E; Brandeis, D; Meyer-Lindenberg, A; Stefánsson, H; Stefansson, Kari (Springer Nature, 2017-04-25)
    Several copy number variants have been associated with neuropsychiatric disorders and these variants have been shown to also influence cognitive abilities in carriers unaffected by psychiatric disorders. Previously, we associated the 15q11.2(BP1–BP2) ...
  • Sá Couto, André; Ryzhakov, Alexey; Loftsson, Thorsteinn (MDPI AG, 2018-10-13)
    It is extremely important for pharmaceutical formulators to have analytical methodology that provides efficient detection and quantification of HPβCD aggregates. Five different methods were then evaluated for their potential to detect these aggregates ...
  • Plomp, Kimberly A.; Dobney, Keith; Weston, Darlene A.; Viðarsdóttir, Una Strand; Collard, Mark (Springer Science and Business Media LLC, 2019-12-16)
    Background: Recently we proposed an evolutionary explanation for a spinal pathology that afflicts many people, intervertebral disc herniation (Plomp et al. [2015] BMC Evolutionary Biology 15, 68). Using 2D data, we found that the bodies and pedicles ...
  • Di, Xiaxia; Rouger, Caroline; Hardardottir, Ingibjorg; Freysdottir, Jona; Molinski, Tadeusz; Tasdemir, Deniz; Omarsdottir, Sesselja (MDPI AG, 2018-11-08)
    An UPLC-qTOF-MS-based dereplication study led to the targeted isolation of seven bromoindole alkaloids from the sub-Arctic sponge Geodia barretti. This includes three new metabolites, namely geobarrettin A–C (1–3) and four known compounds, barettin ...
  • Rich, Anna; Baldwin, David; Alfageme, Inmaculada; Beckett, Paul; Berghmans, Thierry; Brincat, Stephen; Burghuber, Otto; Corlateanu, Alexandru; Cufer, Tanja; Damhuis, Ronald; Danila, Edvardas; Domagala-Kulawik, Joanna; Elia, Stefano; Gaga, Mina; Goksel, Tuncay; Grigoriu, Bogdan; Hillerdal, Gunnar; Huber, Rudolf Maria; Jakobsen, Erik; Jónsson, Steinn; Jovanovic, Dragana; Kavcova, Elena; Konsoulova, Assia; Laisaar, Tanel; Makitaro, Riitta; Mehic, Bakir; Milroy, Robert; Moldvay, Judit; Morgan, Ross; Nanushi, Milda; Paesmans, Marianne; Putora, Paul Martin; Samarzija, Miroslav; Scherpereel, Arnaud; Schlesser, Marc; Sculier, Jean-Paul; Skrickova, Jana; Sotto-Mayor, Renato; Strand, Trond-Eirik; Van Schil, Paul; Blum, Torsten-Gerriet (Springer Science and Business Media LLC, 2018-11-20)
    Background: A minority of European countries have participated in international comparisons with high level data on lung cancer. However, the nature and extent of data collection across the continent is simply unknown, and without accurate data ...
  • Delgado, Alex J; Olafsson, Vilhelm (Dove Medical Press Ltd., 2017-08)
    Xerostomia affects 30% of the population and manifests as a side effect of medications, systemic diseases, or cancer therapy. Oral moisturizers are prescribed to overcome the ailments of dry mouth and its symptoms. It is imperative that these products ...
  • Helgason, Dadi (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-06)
    Acute kidney injury (AKI) is a growing problem worldwide and is associated with high morbidity and mortality. AKI is a known complication following cardiac operations and coronary angiography (CA). Following CA, AKI has been associated with contrast ...
  • Helgadottir, Solveig (University of Iceland, School of Health Sciences, Faculty of Medicine, 2017-01-06)
    In line with advances in surgery, perioperative care, and intensive care, the outcome in patients treated for cardiovascular disease has improved. Open-heart surgery is common in most western countries and, in line with the general ageing of populations, ...
  • Long, Thorir E (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-12)
    Acute kidney injury (AKI) is a common clinical problem both in the hospital and outpatient setting and is associated with increased morbidity and mortality. Chronic kidney disease (CKD) is a risk factor for developing AKI and AKI is a risk factor for ...
  • Edmunds, Kyle; Gíslason, Magnús; Sigurðsson, Sigurður; Gudnason, Vilmundur; Harris, Tamara; Carraro, Ugo; Gargiulo, Paolo (Public Library of Science (PLoS), 2018-03-07)
    Sarcopenic muscular degeneration has been consistently identified as an independent risk factor for mortality in aging populations. Recent investigations have realized the quantitative potential of computed tomography (CT) image analysis to describe ...
  • Ingimarsson, Oddur (University of Iceland, School of Health Sciences, Faculty of Medicine, 2018-04-10)
    Background: Schizophrenia is a chronic serious mental disorder with prevalence close to 0.7%. Early symptoms of schizophrenia generally appear in late adolescence or the early twenties. The prognosis is usually worse in cases of early onset. The ...
  • Ólafsdóttir, Þórunn Ásta; Alexandersson, Kristján F.; Sveinbjornsson, Gardar; Lapini, Giulia; Palladino, Laura; Montomoli, Emanuele; Del Giudice, Giuseppe; Gudbjartsson, Daniel; Jonsdottir, Ingileif (Frontiers Media SA, 2018-01-08)
    Influenza vaccination remains the best strategy for the prevention of influenza virus-related disease and reduction of disease severity and mortality. However, there is large individual variation in influenza vaccine responses. In this study, we ...
  • Jónsson, Helgi (Springer Nature, 2017-12)
    Background: Hand photography has been used in a number of studies to determine the presence and severity of hand osteoarthritis (HOA). The aim of this study was to present age and gender specific prevalences of HOA diagnosed by this method. Methods: ...
  • Kuiper, Ingrid N.; Svanes, Cecilie; Benediktsdóttir, Bryndís; Bertelsen, Randi J.; Bråbäck, Lennart; Dharmage, Shyamali C.; Holm, Mathias; Janson, Christer; Jögi, Rain; Malinovschi, Andrei; Matheson, Melanie; Moratalla, Jesús Martínez; Real, Francisco Gómez; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Timm, Signe; Johannessen, Ane (Springer Nature, 2018-07-27)
    Background Self-report questionnaires are commonly used in epidemiology, but may be susceptible to misclassification, especially if answers are given on behalf of others, e.g. children or parents. The aim was to determine agreement and analyse predictors ...
  • Hjaltadóttir, Ingibjörg; Sigurdardottir, Arun K. (Læknafélag Íslands, 2015-02)
    Inngangur: Sykursýki er vaxandi vandamál meðal eldra fólks og einn af áhættuþáttum fyrir flutning á hjúkrunarheimili. Ennfremur er sjúkdómabyrði og lyfjanotkun þeirra sem eru með sykursýki oft meiri. Tilgangur rannsóknarinnar var að skoða algengi ...
  • Roper, Lucinda; Tran, Duong Thuy; Einarsdóttir, Kristjana; Preen, David B.; Havard, Alys (Public Library of Science (PLoS), 2018-08-30)
    Background The linkage of routine data collections are valuable for population-based evaluation of smoking cessation pharmacotherapy in pregnancy where little is known about the utilisation or safety of these pharmacotherapies antenatally. The use of ...
  • Xu, Maonian; Eiriksson, Finnur Freyr; Thorsteinsdóttir, Margrét; Heiðmarsson, Starri; Omarsdottir, Sesselja; Olafsdottir, Elin Soffia (Elsevier BV, 2019-04)
    The club moss family Lycopodiaceae produces a diverse array of bioactive lycopodium alkaloids (LAs). In particular, the alkaloid huperzine A (hupA) has grasped attention since it is a potent acetylcholinesterase inhibitor of medical interest in Alzheimer's ...
  • Sapkota, Yadav; De Vivo, Immaculata; Steinthorsdottir, Valgerdur; Fassbender, Amelie; Bowdler, Lisa; Buring, Julie E.; Edwards, Todd L.; Jones, Sarah; Dorien, O.; Peterse, Danielle; Rexrode, Kathryn M.; Ridker, Paul M.; Schork, Andrew J.; Thorleifsson, Gudmar; Wallace, Leanne M.; Kraft, Peter; Morris, Andrew P.; Nyholt, Dale R.; Edwards, Digna R. Velez; Nyegaard, Mette; D'Hooghe, Thomas; Chasman, Daniel I.; Stefansson, Kari; Missmer, Stacey A.; Montgomery, Grant W. (Springer Nature, 2017-09)
    Genome-wide association (GWA) studies have identified 19 independent common risk loci for endometriosis. Most of the GWA variants are non-coding and the genes responsible for the association signals have not been identified. Herein, we aimed to assess ...