Opin vísindi

Browsing by Department "Lífvísindasetur (HÍ)"

Browsing by Department "Lífvísindasetur (HÍ)"

Sort by: Order: Results:

  • Di, Xiaxia; Rouger, Caroline; Hardardottir, Ingibjorg; Freysdottir, Jona; Molinski, Tadeusz; Tasdemir, Deniz; Omarsdottir, Sesselja (MDPI AG, 2018-11-08)
    An UPLC-qTOF-MS-based dereplication study led to the targeted isolation of seven bromoindole alkaloids from the sub-Arctic sponge Geodia barretti. This includes three new metabolites, namely geobarrettin A–C (1–3) and four known compounds, barettin ...
  • Káradóttir, Harpa; Nikhil Nitin, Kulkarn; Guðjónsson, Þórarinn; Karason, Sigurbergur; Guðmundsson, Guðmundur Hrafn (PeerJ, 2015-12-07)
    Mechanical ventilation (MV) of patients can cause damage to bronchoalveolar epithelium, leading to a sterile inflammatory response, infection and in severe cases sepsis. Limited knowledge is available on the effects of MV on the innate immune defense ...
  • Pashay Ahi, Ehsan; Steinhäuser, Sophie S.; Palsson, Arnar; Franzdottir, Sigridur Rut; Snorrason, Sigurdur S.; Maier, Valerie H.; Jónsson, Zophonías Oddur (Springer Nature, 2015-09-16)
    Background The developmental basis of craniofacial morphology hinges on interactions of numerous signalling systems. Extensive craniofacial variation in the polymorphic Arctic charr, a member of the salmonid family, from Lake Thingvallavatn (Iceland), ...
  • Guðbrandsson, Jóhannes; Franzdottir, Sigridur Rut; Kristjansson, Bjarni K.; Pashay Ahi, Ehsan; Maier, Valerie H.; Kapralova, Kalina H.; Snorrason, Sigurdur S; Jónsson, Zophonías Oddur; Palsson, Arnar (PeerJ, 2018-02-07)
    Phenotypic differences between closely related taxa or populations can arise through genetic variation or be environmentally induced, leading to altered transcription of genes during development. Comparative developmental studies of closely related ...
  • Quirk, Sigríður Júlía; Haraldsson, Gunnsteinn; Erlendsdóttir, Helga; Hjálmarsdóttir, Martha Ásdís; van Tonder, Andries J.; Hrafnkelsson, Birgir; Sigurdsson, Samuel; Bentley, Stephen D.; Haraldsson, Ásgeir; Brueggemann, Angela B.; Kristinsson, Karl G. (American Society for Microbiology, 2018-09-26)
    Vaccination with pneumococcal conjugate vaccines (PCVs) disrupts the pneumococcal population. Our aim was to determine the impact of the 10-valent PCV on the serotypes, genetic lineages, and antimicrobial susceptibility of pneumococci isolated from ...
  • Guðbrandsson, Jóhannes; Kapralova, Kalina; Franzdottir, Sigridur Rut; Bergsveinsdóttir, Þóra Margrét; Hafstað, Völundur; Jónsson, Zophonías Oddur; Snorrason, Sigurður S.; Palsson, Arnar (Wiley, 2019-09-12)
    The availability of diverse ecological niches can promote adaptation of trophic specializations and related traits, as has been repeatedly observed in evolutionary radiations of freshwater fish. The role of genetics, environment, and history in ...
  • Gudmundsson, Julius; Sigurðsson, Jón K.; Stefánsdóttir, Lilja; Agnarsson, Bjarni A.; Ísaksson, Helgi J.; Stefánsson, Ólafur A.; Guðjónsson, Sigurjón Axel; Gudbjartsson, Daniel; Másson, Gísli; Frigge, Michael L.; Stacey, Simon N.; Sulem, Patrick; Halldorsson, Gisli; Tragante, Vinicius; Holm, Hilma; Eyjólfsson, Guðmundur I.; Sigurðardóttir, Ólöf; Olafsson, Isleifur; Jónsson, Þorvaldur; Jónsson, Eirikur; Barkardóttir, Rósa B.; Hilmarsson, Rafn; Asselbergs, Folkert W.; Geirsson, Guðmundur; Thorsteinsdottir, Unnur; Rafnar, Thorunn; Thorleifsson, Gudmar; Stefansson, Kari (Springer Science and Business Media LLC, 2018-11-08)
    Benign prostatic hyperplasia and associated lower urinary tract symptoms (BPH/LUTS) are common conditions affecting the majority of elderly males. Here we report the results of a genome-wide association study of symptomatic BPH/LUTS in 20,621 patients ...
  • Rekha, Rokeya Sultana; Mily, Akhirunnesa; Sultana, Tajnin; Haq, Ahsanul; Ahmed, Sultan; Mostafa Kamal, S. M.; van Schadewijk, Annemarie; Hiemstra, Pieter S.; Guðmundsson, Guðmundur Hrafn; Agerberth, Birgitta; Raqib, Rubhana (Springer Nature, 2018-07-04)
    Background We have previously shown that 8 weeks’ treatment with phenylbutyrate (PBA) (500mgx2/day) with or without vitamin D3 (vitD3) (5000 IU/day) as host-directed therapy (HDT) accelerated clinical recovery, sputum culture conversion and increased ...
  • Pan, Li-Long; Deng, Yuan-Yuan; Wang, Ruxing; Wu, Chengfei; Li, Jiahong; Niu, Wenying; Yang, Qin; Bhatia, Madhav; Guðmundsson, Guðmundur Hrafn; Agerberth, Birgitta; Diana, Julien; Sun, Jia (Frontiers Media SA, 2018-04-17)
    Acute pancreatitis (AP) is one common clinical acute abdominal disease, for which specific pharmacological or nutritional therapies remain elusive. Lactose, a macronutrient and an inducer of host innate immune responses, possesses immune modulatory ...
  • Halldorsson, Skarphedinn; Rohatgi, Neha; Magnúsdóttir, Manuela; Choudhary, Kumari Sonal; Gudjonsson, Thorarinn; Knutsen, Erik; Barkovskaya, Anna; Hilmarsdóttir, Bylgja; Perander, Maria; Mælandsmo, Gunhild M.; Guðmundsson, Steinn; Rolfsson, Óttar (Elsevier BV, 2017-06)
    Epithelial to mesenchymal transition (EMT) has implications in tumor progression and metastasis. Metabolic alterations have been described in cancer development but studies focused on the metabolic re-wiring that takes place during EMT are still limited. ...
  • Guðmundsson, Bjarki; Þormar, Hans G; Sigurðsson, Albert; Dankers, Wendy; Steinarsdóttir, Margrét; Hermanowicz, Stefan; Sigurðsson, Stefán; Ólafsson, Davið; Halldorsdottir, Anna; Meyn, Stephen; Jonsson, Jon J. (Oxford University Press (OUP), 2018-07-24)
    DNA damage assays have various limitations in types of lesions detected, sensitivity, specificity and samples that can be analyzed. The Northern Lights Assay (NLA) is based on 2D Strandness-Dependent Electrophoresis (2D-SDE), a technique that separates ...
  • Teitsdóttir, Unnur Diljá; Arnardóttir, Erna Sif; Björnsdóttir, Erla; Gíslason, Þórarinn; Petersen, Petur Henry (Springer Nature, 2018-10-11)
    Purpose The inflammatory markers chitinase-3-like protein 1 (CHI3L1) and chitotriosidase (CHIT1) have both been associated with cardiovascular complications. The aim of this preliminary observational study was to assess the roles and interaction ...
  • Ogmundsdottir, Margret H; Fock, V.; Sooman, L.; Pogenberg, V.; Dilshat, R.; Bindesbøll, C.; Ogmundsdottir, H. M.; Simonsen, A.; Wilmanns, M.; Steingrimsson, Eirikur (Springer Science and Business Media LLC, 2018-09-26)
    Autophagy is a degradation pathway important for cellular homeostasis. The E1-like enzyme ATG7 is a key component of the autophagy machinery, with the main function of mediating the lipidation of LC3/GABARAP during autophagosome formation. By analysing ...
  • Evin, Allowen; Owen, Joseph; Larson, Greger; Debiais-Thibaud, Mélanie; Cucchi, Thomas; Viðarsdóttir, Una Strand; Dobney, Keith (The Royal Society, 2017-08)
    Domestic animals are often described as paedomorphic, meaning that they retain juvenile characteristics into adulthood. Through a three-dimensional landmark-based geometric morphometric analysis of cranial morphology at three growth stages, we ...
  • Pashay Ahi, Ehsan; Kapralova, Kalina H.; Palsson, Arnar; Maier, Valerie; Guðbrandsson, Jóhannes; Snorrason, Sigurdur S; Jónsson, Zophonías Oddur; Franzdottir, Sigridur Rut (Springer Nature, 2014)
    Background Understanding the molecular basis of craniofacial variation can provide insights into key developmental mechanisms of adaptive changes and their role in trophic divergence and speciation. Arctic charr (Salvelinus alpinus) is a polymorphic ...