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Browsing by Author "Rappuoli, Rino"

Browsing by Author "Rappuoli, Rino"

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    Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM197 conjugate vaccine 
    Micoli, Francesca; Bjarnarson, Stefania P.; Arcuri, Melissa; Pind, Audur Anna Aradottir; Magnusdottir, Gudbjorg J.; Necchi, Francesca; Di Benedetto, Roberta; Carducci, Martina; Schiavo, Fabiola; Giannelli, Carlo; Pisoni, Ivan; Martin, Laura B.; Del Giudice, Giuseppe; MacLennan, Calman A.; Rappuoli, Rino; Jonsdottir, Ingileif; Saul, Allan (2020-09-29)
    Polysaccharide-protein conjugates have been developed to overcome the T-independent response, hyporesponsiveness to repeated vaccination, and poor immunogenicity in infants of polysaccharides. To address the impact of polysaccharide length, typhoid ...