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Fletta eftir höfundi "Guðjónsson, Þorkell"

Fletta eftir höfundi "Guðjónsson, Þorkell"

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    CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer 
    Stefansson, Olafur; Hermanowicz, Stefan; van der Horst, Jasper; Hilmarsdóttir, Hólmfríður; Staszczak, Zuzanna; Jónasson, Jón Gunnlaugur; Tryggvadottir, Laufey; Guðjónsson, Þorkell; Sigurðsson, Stefán (Springer Nature, 2017-07-05)
    Background DNA repair of alkylation damage is defective in various cancers. This occurs through somatically acquired inactivation of the MGMT gene in various cancer types, including breast cancers. In addition to MGMT, the two E. coli AlkB homologs ...
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    Profiling DNA damage response following mitotic perturbations 
    Pedersen, Ronni S.; Karemore, Gopal; Guðjónsson, Þorkell; Rask, Maj-Britt; Neumann, Beate; Hériché, Jean-Karim; Pepperkok, Rainer; Ellenberg, Jan; Gerlich, Daniel W.; Lukas, Jiri; Lukas, Claudia (Springer Nature, 2016-12-15)
    Genome integrity relies on precise coordination between DNA replication and chromosome segregation. Whereas replication stress attracted much attention, the consequences of mitotic perturbations for genome integrity are less understood. Here, we knockdown ...