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Fletta eftir höfundi "Emilsson, Valur"

Fletta eftir höfundi "Emilsson, Valur"

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    ACE2 levels are altered in comorbidities linked to severe outcome in COVID-19 
    Emilsson, Valur; Gudmundsson, Elias F; Aspelund, Thor; Jonsson, Brynjolfur G; Gudjonsson, Alexander; Launer, Lenore J.; Lamb, John R; Gudmundsdottir, Valborg; Jennings, Lori L; Gudnason, Vilmundur (2020-06-05)
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    Antihypertensive medication uses and serum ACE2 levels 
    Emilsson, Valur; Gudmundsson, Elias F.; Aspelund, Thor; Jonsson, Brynjolfur G.; Gudjonsson, Alexander; Launer, Lenore J.; Jennings, Lori L.; Gudmundsdottir, Valborg; Gudnason, Vilmundur (2020-05-25)
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    Coding and regulatory variants affect serum protein levels and common disease 
    Emilsson, Valur; Gudmundsdottir, Valborg; Ilkov, Marjan; Staley, James R; Gudmundsson, Elias F; Launer, Lenore J; Lindeman, Jan H; Morton, Nicholas M; Aspelund, Thor; Lamb, John R; Jennings, Lori L; Gudnason, Vilmundur; Gudjonsson, Alexander; Karim, Mohd A; Jonsson, Brynjolfur G (2020-05-08)
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    Coding and regulatory variants are associated with serum protein levels and disease 
    Emilsson, Valur; Gudmundsdottir, Valborg; Gudjonsson, Alexander; Jonmundsson, Thorarinn; Jonsson, Brynjolfur G; Karim, Mohd A; Ilkov, Marjan; Staley, James R; Gudmundsson, Elias F; Launer, Lenore J; Lindeman, Jan H; Morton, Nicholas M; Aspelund, Thor; Lamb, John R; Jennings, Lori L; Gudnason, Vilmundur (2022-01-25)
    Circulating proteins can be used to diagnose and predict disease-related outcomes. A deep serum proteome survey recently revealed close associations between serum protein networks and common disease. In the current study, 54,469 low-frequency and common ...
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    Integrated Human Evaluation of the Lysophosphatidic Acid Pathway as a Novel Therapeutic Target in Atherosclerosis 
    Aldi, Silvia; Matic, Ljubica Perisic; Hamm, Gregory; van Keulen, Daniëlle; Tempel, Dennie; Holmstrøm, Kim; Szwajda, Agnieszka; Nielsen, Boye Schnack; Emilsson, Valur; Ait-Belkacem, Rima; Lengquist, Mariette; Paulsson-Berne, Gabrielle; Eriksson, Per; Lindeman, Jan H.N.; Gool, Alain J.; Stauber, Jonathan; Hedin, Ulf; Hurt-Camejo, Eva (Elsevier BV, 2018-09-21)
    Variants in thePLPP3gene encoding for lipid phosphatephosphohydrolase 3 have been associated with susceptibilityto atherosclerosis independently of classical risk factors.PLPP3 inactivates lysophosphatidic acid (LPA), a pro-inflam-matory, pro-thrombotic ...
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    Oncostatin M reduces atherosclerosis development in APOE3Leiden.CETP mice and is associated with increased survival probability in humans 
    van Keulen, Danielle; Pouwer, Marianne G.; Emilsson, Valur; Matic, Ljubica Perisic; Pieterman, Elsbet J.; Hedin, Ulf; Gudnason, Vilmundur; Jennings, Lori L.; Holmstrøm, Kim; Nielsen, Boye Schnack; Pasterkamp, Gerard; Lindeman, Jan H.N.; van Gool, Alain J.; Sollewijn Gelpke, Maarten D.; Princen, Hans M.G.; Tempel, Dennie (2019-08-01)
    Objective Previous studies indicate a role for Oncostatin M (OSM) in atherosclerosis and other chronic inflammatory diseases for which inhibitory antibodies are in development. However, to date no intervention studies with OSM have been performed, and ...
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    A proteogenomic signature of age-related macular degeneration in blood 
    Emilsson, Valur; Gudmundsson, Elias F; Jonmundsson, Thorarinn; Jonsson, Brynjolfur G; Twarog, Michael; Gudmundsdottir, Valborg; Li, Zhiguang; Finkel, Nancy; Poor, Stephen; Liu, Xin; Esterberg, Robert; Zhang, Yiyun; Jose, Sandra; Huang, Chia-Ling; Liao, Sha-Mei; Loureiro, Joseph; Zhang, Qin; Grosskreutz, Cynthia L; Nguyen, Andrew A; Huang, Qian; Leehy, Barrett; Pitts, Rebecca; Aspelund, Thor; Lamb, John R; Jonasson, Fridbert; Launer, Lenore J; Cotch, Mary Frances; Jennings, Lori L; Gudnason, Vilmundur; Walshe, Tony E (2022-06-13)
    Age-related macular degeneration (AMD) is one of the most common causes of visual impairment in the elderly, with a complex and still poorly understood etiology. Whole-genome association studies have discovered 34 genomic regions associated with AMD. ...
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    A proteome-wide genetic investigation identifies several sars-cov-2-exploited host targets of clinical relevance 
    Karim, Mohd A.; Shilts, Jarrod; Schwartzentruber, Jeremy; Hayhurst, James; Buniello, Annalisa; Mohammed, Elmutaz Shaikho Elhaj; Zheng, Jie; Holmes, Michael V.; Ochoa, David; Carmona, Miguel; Maranville, Joseph; Gaunt, Tom R.; Emilsson, Valur; Guðnason, Vilmundur G.; McDonagh, Ellen M.; Wright, Gavin J.; Ghoussaini, Maya; Dunham, Ian (2021-08-17)
    Background: The virus SARS-CoV-2 can exploit biological vulnerabilities (e.g. host proteins) in susceptible hosts that predispose to the development of severe COVID-19. Methods: To identify host proteins that may contribute to the risk of severe COVID-19, ...
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    Serum levels of ACE2 are higher in patients with obesity and diabetes 
    Emilsson, Valur; Guðmundsson, Elías F.; Aspelund, Thor; Jónsson, Brynjólfur G.; Guðjónsson, Alexander; Launer, Lenore J.; Lamb, John R.; Guðmundsdóttir, Valborg; Jennings, Lori L.; Guðnason, Vilmundur G. (2020-12-16)
    Objective: As severity of outcome in COVID-19 is disproportionately higher among individuals with obesity, smokers, patients with hypertension, kidney disease, chronic pulmonary disease, coronary heart disease (CHD), and/or type 2 diabetes (T2D), serum ...