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Fletta eftir höfundi "Lathrop, Mark"

Fletta eftir höfundi "Lathrop, Mark"

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    Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis 
    Chen, Hao Yu; Cairns, Benjamin J.; Small, Aeron M.; Burr, Hannah A.; Ambikkumar, Athithan; Martinsson, Andreas; Thériault, Sébastien; Munter, Hans Markus; Steffen, Brian; Zhang, Richard; Levinson, Rebecca T.; Shaffer, Christian M.; Rong, Jian; Sonestedt, Emily; Dufresne, Line; Ljungberg, Johan; Näslund, Ulf; Johansson, Bengt; Ranatunga, Dilrini K.; Whitmer, Rachel A.; Budoff, Matthew J.; Nguyen, Albert; Vasan, Ramachandran S.; Larson, Martin G.; Harris, William S.; Damrauer, Scott M.; Stark, Ken D.; Boekholdt, S. Matthijs; Wareham, Nicholas J.; Pibarot, Philippe; Arsenault, Benoit J.; Mathieu, Patrick; Gudnason, Vilmundur; O’Donnell, Christopher J.; Rotter, Jerome I.; Tsai, Michael Y.; Post, Wendy S.; Clarke, Robert; Söderberg, Stefan; Bossé, Yohan; Wells, Quinn S.; Smith, J. Gustav; Rader, Daniel J.; Lathrop, Mark; Engert, James C.; Thanassoulis, George (American Medical Association (AMA), 2020-06-01)
    Importance: Aortic stenosis (AS) has no approved medical treatment. Identifying etiological pathways for AS could identify pharmacological targets. Objective: To identify novel genetic loci and pathways associated with AS. Design, Setting, and Participants: ...
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    Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate 
    Mishra, Aniket; Duplaà, Cecile; Vojinovic, Dina; Suzuki, Hideaki; Sargurupremraj, Muralidharan; Zilhão, Nuno R.; Li, Shuo; Bartz, Traci M.; Jian, Xueqiu; Zhao, Wei; Hofer, Edith; Wittfeld, Katharina; Harris, Sarah E.; Van Der Auwera-Palitschka, Sandra; Luciano, Michelle; Bis, Joshua C.; Adams, Hieab H.H.; Satizabal, Claudia L.; Gottesman, Rebecca F.; Gampawar, Piyush G.; Bülow, Robin; Weiss, Stefan; Yu, Miao; Bastin, Mark E.; Lopez, Oscar L.; Vernooij, Meike W.; Beiser, Alexa S.; Völker, Uwe; Kacprowski, Tim; Soumare, Aicha; Smith, Jennifer A.; Knopman, David S.; Morris, Zoe; Zhu, Yicheng; Rotter, Jerome I.; Dufouil, Carole; Valdes Hernández, Maria; Muñoz Maniega, Susana; Lathrop, Mark; Boerwinkle, Erik; Schmidt, Reinhold; Ihara, Masafumi; Mazoyer, Bernard; Yang, Qiong; Joutel, Anne; Tournier-Lasserve, Elizabeth; Launer, Lenore J.; Deary, Ian J.; Mosley, Thomas H.; Gudnason, Vilmundur (2022-06-01)
    Cerebral small vessel disease is a leading cause of stroke and a major contributor to cognitive decline and dementia, but our understanding of specific genes underlying the cause of sporadic cerebral small vessel disease is limited. We report a genome-wide ...