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Fletta eftir höfundi "Guchelaar, Henk Jan"

Fletta eftir höfundi "Guchelaar, Henk Jan"

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    Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39 
    Spiliopoulou, Athina; Colombo, Marco; Plant, Darren; Nair, Nisha; Cui, Jing; Coenen, Marieke J.H.; Ikari, Katsunori; Yamanaka, Hisashi; Saevarsdottir, Saedis; Padyukov, Leonid; Bridges, S. Louis; Kimberly, Robert P.; Okada, Yukinori; Van Riel, Piet L.C.M.; Wolbink, Gertjan; Van Der Horst-Bruinsma, Irene E.; De Vries, Niek; Tak, Paul P.; Ohmura, Koichiro; Canhão, Helena; Guchelaar, Henk Jan; Huizinga, Tom W.J.; Criswell, Lindsey A.; Raychaudhuri, Soumya; Weinblatt, Michael E.; Wilson, Anthony G.; Mariette, Xavier; Isaacs, John D.; Morgan, Ann W.; Pitzalis, Costantino; Barton, Anne; Mckeigue, Paul (2019-08-01)
    Objectives We sought to investigate whether genetic effects on response to TNF inhibitors (TNFi) in rheumatoid arthritis (RA) could be localised by considering known genetic susceptibility loci for relevant traits and to evaluate the usefulness of these ...
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    A Genetic Polymorphism in CTLA-4 Is Associated with Overall Survival in Sunitinib-Treated Patients with Clear Cell Metastatic Renal Cell Carcinoma 
    Liu, Xiaoyan; Swen, Jesse J.; Diekstra, Meta H.M.; Boven, Epie; Castellano, Daniel; Gelderblom, Hans; Mathijssen, Ron H.J.; Vermeulen, Sita H.; Oosterwijk, Egbert; Junker, Kerstin; Roessler, Max; Alexiusdottir, Kristin; Sverrisdóttir, Ásgerður; Radu, Marius T.; Ambert, Valentin; Eisen, Tim; Warren, Anne; Rodríguez-Antona, Cristina; García-Donas, Jesus; Böhringer, Stefan; Koudijs, Karel K.M.; Kiemeney, Lambertus A.L.M.; Rini, Brian I.; Guchelaar, Henk-Jan (2018-05-15)
    Purpose: The survival of patients with clear cell metastatic renal cell carcinoma (cc-mRCC) has improved substantially since the introduction of tyrosine kinase inhibitors (TKI). With the fact that TKIs interact with immune responses, we investigated ...