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Browsing by Author "Klareskog, Lars"

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Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells : Implications for a Bacterial Origin in RA Etiology

Sherina, Natalia; de Vries, Charlotte; Kharlamova, Nastya; Sippl, Natalie; Jiang, Xia; Brynedal, Boel; Kindstedt, Elin; Hansson, Monika; Mathsson-Alm, Linda; Israelsson, Lena; Stålesen, Ragnhild; Saevarsdottir, Saedis; Holmdahl, Rikard; Hensvold, Aase; Johannsen, Gunnar; Eriksson, Kaja; Sallusto, Federica; Catrina, Anca I.; Rönnelid, Johan; Grönwall, Caroline; Yucel-Lindberg, Tülay; Alfredsson, Lars; Klareskog, Lars; Piccoli, Luca; Malmström, Vivianne; Amara, Khaled; Lundberg, Karin (2022-04-20)

Based on the epidemiological link between periodontitis and rheumatoid arthritis (RA), and the unique feature of the periodontal bacterium Porphyromonas gingivalis to citrullinate proteins, it has been suggested that production of anti-citrullinated ...
Anti–Citrullinated Protein Antibody Specificities, Rheumatoid Factor Isotypes, and Incident Cardiovascular Events in Patients With Rheumatoid Arthritis

Westerlind, Helga; Rönnelid, Johan; Hansson, Monika; Alfredsson, Lars; Mathsson‐Alm, Linda; Serre, Guy; Cornillet, Martin; Holmdahl, Rikard; Jakobsson, Per‐Johan; Skriner, Karl; Klareskog, Lars; Saevarsdottir, Saedis; Askling, Johan (Wiley, 2020-09-07)

Objective: To investigate the relationship between anti–citrullinated protein antibodies (ACPAs), specific ACPA subspecificities, rheumatoid factor (RF) isotypes, and incident cardiovascular (CV) events in patients with rheumatoid arthritis (RA). ...
A Comprehensive Evaluation of the Relationship Between Different IgG and IgA Anti-Modified Protein Autoantibodies in Rheumatoid Arthritis

Grönwall, Caroline; Liljefors, Lisa; Bang, Holger; Hensvold, Aase H.; Hansson, Monika; Mathsson-Alm, Linda; Israelsson, Lena; Joshua, Vijay; Svärd, Anna; Stålesen, Ragnhild; Titcombe, Philip J.; Steen, Johanna; Piccoli, Luca; Sherina, Natalia; Clavel, Cyril; Svenungsson, Elisabet; Gunnarsson, Iva; Sævarsdóttir, Sædís; Kastbom, Alf; Serre, Guy; Alfredsson, Lars; Malmström, Vivianne; Rönnelid, Johan; Catrina, Anca I.; Lundberg, Karin; Klareskog, Lars (2021-05-20)

Seropositive rheumatoid arthritis (RA) is characterized by the presence of rheumatoid factor (RF) and anti-citrullinated protein autoantibodies (ACPA) with different fine-specificities. Yet, other serum anti-modified protein autoantibodies (AMPA), e.g. ...
Is tea consumption associated with reduction of risk of rheumatoid arthritis? A Swedish case-control study

Westerlind, Helga; Palmqvist, Ida; Saevarsdottir, Saedis; Alfredsson, Lars; Klareskog, Lars; Di Giuseppe, Daniela (2021-08-07)

BACKGROUND: Tea is a popular beverage around the world and has properties that can affect the immune system. The association between tea consumption and the risk of rheumatoid arthritis (RA), a chronic autoimmune disease primarily affecting the joints, ...
Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis : results from the Swedish EIRA study

Hedenstierna, Louise; Hedström, Anna Karin; Klareskog, Lars; Di Giuseppe, Daniela; Alfredsson, Lars; Askling, Johan; Ernestam, Sofia; Saevarsdottir, Saedis; Ljung, Lotta (2022-08-23)

Objectives: To investigate the association between psychosocial vulnerability, defined as either low social support or low decision latitude at work, and disease remission at 3, 12, and 60 months in patients with rheumatoid arthritis (RA). Methods: ...
Sleep problems in rheumatoid arthritis over 12 years from diagnosis : Results from the Swedish EIRA study

Lyne, Lauren; Åkerstedt, Torbjörn; Alfredsson, Lars; Lehtonen, Tiina; Sævarsdóttir, Sædís; Klareskog, Lars; Westerlind, Helga (2022-01-05)

Objective Most studies of rheumatoid arthritis (RA) and sleep have focused on established RA. We here investigate sleep quality and sleep duration in patients with newly diagnosed RA and during 1-12 years after diagnosis. Methods Data were collected ...

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