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Browsing by Author "Amirfallah, Arsalan"

Browsing by Author "Amirfallah, Arsalan"

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  • Amirfallah, Arsalan; Kocal, Gizem; Unal, Olcun; Ellidokuz, Hulya; Oztop, Ilhan; Basbinar, Yasemin (MDPI AG, 2018-12-13)
    Fluoropyrimidine-based chemotherapy is extensively used for the treatment of solid cancers, including colorectal cancer. However, fluoropyrimidine-driven toxicities are a major problem in the management of the disease. The grade and type of the ...
  • Amirfallah, Arsalan; Arason, Adalgeir; Einarsson, Hjörleifur; Guðmundsdóttir, Eydís Þórunn; Freysteinsdóttir, Edda Sigríður; Ólafsdóttir, Kristrún Auður; Jóhannsson, Óskar Þór; Agnarsson, Bjarni A.; Barkardottir, Rosa Bjork; Reynisdottir, Inga (Public Library of Science (PLoS), 2019-08-23)
    Background: Fusion genes result from genomic structural changes, which can lead to alterations in gene expression that supports tumor development. The aim of the study was to use fusion genes as a tool to identify new breast cancer (BC) genes with a ...
  • Amirfallah, Arsalan; Knutsdottir, Hildur; Arason, Aðalgeir; Hilmarsdóttir, Bylgja; Jóhannsson, Óskar Þór; Agnarsson, Bjarni Agnar; Barkardottir, Rosa B.; Reynisdottir, Inga (2021-11-19)
    Breast cancer is the cancer most often diagnosed in women. MicroRNAs (MIRs) are short RNA molecules that bind mRNA resulting in their downregulation. MIR21 has been shown to be an oncomiR in most cancer types, including breast cancer. Most of the effects ...
  • Amirfallah, Arsalan (University of Iceland, School of Health Sciences, Faculty of Medicine, 2021-06-15)
    Breast cancer is the most common type of cancer in women worldwide. It is also a highly heterogeneous disease that is characterized by an array of genetic rearrangements, including copy number alterations (CNA), translocations, inversions, ...