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Population Genomic Molecular Epidemiological Study of Macrolide-Resistant Streptococcus pyogenes in Iceland, 1995 to 2016: Identification of a Large Clonal Population with a pbp2x Mutation Conferring Reduced In Vitro β-Lactam Susceptibility

Southon, Sara B.; Beres, Stephen B.; Kachroo, Priyanka; Saavedra, Matthew Ojeda; Erlendsdóttir, Helga; Haraldsson, Gunnsteinn; Yerramilli, Prasanti; Pruitt, Layne; Zhu, Luchang; Musser, James M.; Kristinsson, Karl G. (American Society for Microbiology, 2020-06-10)

Resistance to macrolide antibiotics is a global concern in the treatment of Streptococcus pyogenes (group A Streptococcus [GAS]) infections. In Iceland, since the detection of the first macrolide-resistant isolate in 1998, three epidemic waves of ...

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