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Browsing by Author "Eysteinsson, Thor"

Browsing by Author "Eysteinsson, Thor"

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    Carbonic Anhydrase Inhibitors of Different Structures Dilate Pre-Contracted Porcine Retinal Arteries 
    Eysteinsson, Thor; Guðmundsdóttir, Hrönn; Harðarson, Arnar Össur; Berrino, Emanuela; Selleri, Silvia; Supuran, Claudiu; carta, fabrizio (MDPI AG, 2019-01-22)
    Carbonic anhydrase inhibitors (CAIs), such as dorzolamide (DZA), are used as anti-glaucoma drugs to lower intraocular pressure, but it has been found that some of these drugs act as vasodilators of retinal arteries. The exact mechanism behind the ...
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    The microphthalmia-associated transcription factor (Mitf) gene and its role in regulating eye function 
    García-Llorca, Andrea; Gudmundsdottir Aspelund, Snaefridur; Ogmundsdottir, Margret H; Steingrimsson, Eirikur; Eysteinsson, Thor (Springer Science and Business Media LLC, 2019-10-28)
    Mutations in the microphthalmia-associated transcription factor (Mitf) gene can cause retinal pigment epithelium (RPE) and retinal dysfunction and degeneration. We examined retinal and RPE structure and function in 3 month old mice homo- or heterozygous ...
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    Mitf Links Neuronal Activity and Long-Term Homeostatic Intrinsic Plasticity 
    Atacho, Diahann A. M.; Reynisson, Hallur; Pétursdóttir, Anna Þóra; Eysteinsson, Thor; Steingrimsson, Eirikur; Petersen, Petur Henry (Society for Neuroscience, 2020-03)
    Neuroplasticity forms the basis for neuronal circuit complexity and differences between otherwise similar circuits. We show that the microphthalmia-associated transcription factor (Mitf) plays a central role in intrinsic plasticity of olfactory bulb ...
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    Mouse microphthalmia-associated transcription factor (Mitf) mutations affect the structure of the retinal vasculature 
    Daníelsson, Stefán Broddi; García-Llorca, Andrea; Reynisson, Hallur; Eysteinsson, Thor (2022-03-29)
    Purpose: Mice carrying pathogenic variants in the microphthalmia transcription factor (Mitf) gene show structural and functional changes in the retina and retinal pigment epithelium. The purpose of this study was to assess the vascular changes in Mitf ...