Browsing by Author "Ballesteros-Álvarez, Josué"

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Mechanism of conditional partner selectivity in MITF/TFE family transcription factors with a conserved coiled coil stammer motif

Pogenberg, Vivian; Ballesteros-Álvarez, Josué; Schober, Romana; Sigvaldadóttir, Ingibjörg; Obarska-Kosinska, Agnieszka; Milewski, Morlin; Schindl, Rainer; Ögmundsdóttir, Margrét Helga; Steingrímsson, Eiríkur; Wilmanns, Matthias (2020-01-24)

Interrupted dimeric coiled coil segments are found in a broad range of proteins and generally confer selective functional properties such as binding to specific ligands. However, there is only one documented case of a basic-helix-loop-helix leucine ...
A network of bHLHZip transcription factors in melanoma: Interactions of MITF, TFEB and TFE3

Ballesteros Álvarez, Josué A (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-01-10)

The MITF, TFEB, TFE3 and TFEC (MiT-TFE) proteins belong to a larger family of basic helix-loop-helix leucine zipper transcription factors that are able to bind DNA and regulate gene expression. MITF is crucial for melanocyte development and has been ...

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