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Browsing by Author "Björnsson, Einar Stefán"
Now showing items 1-20 of 27
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(2019-12-01)Background: Data on the natural history of acute lower gastrointestinal bleeding (ALGIB) are lacking. We evaluated five-year bleeding risk and mortality in ALGIB patients and controls. Furthermore, we aimed to find predictors of rebleeding. Methods: ... -
(2022-07-27)Immunological checkpoint inhibitors (ICIs) have revolutionized therapy of many different malignanices. Concomitant immune-mediated adverse effects are common and can affect many organs such as the skin, lungs, gastrointestinal and endocrine organs as ...
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(2021-06-28)Drug-induced liver injury (DILI) should be considered in all patients with recent elevation of liver tests without obvious etiology and normal hepatobiliary imaging. There is currently no biomarker that is helpful in diagnosis which relies on clinical ...
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Comparison of medication adherence to different oral anticoagulants : population-based cohort study (2023-01-01)OBJECTIVE: Previous observational studies have yielded conflicting results on whether medication adherence differs between patients receiving warfarin and direct oral anticoagulants (DOACs). Importantly, no study has adequately accounted for warfarin ...
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(2022-12-23)In the pivotal randomized controlled trials (RCTs) for patients with atrial fibrillation, direct oral anticoagulants (DOACs) had similar or even superior efficacy and safety compared with warfarin. However, RCTs comparing different DOACs are nonexistent ...
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(2023-07)Idiosyncratic drug-induced liver injury (DILI) is an infrequent but important cause of liver disease. Newly identified causes of DILI include the COVID vaccines, turmeric, green tea extract, and immune checkpoint inhibitors. DILI is largely a clinical ...
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(2019-09)INNGANGUR Frumkomin trefjunargallgangabólga er langvinnur bólgusjúkdómur í gallvegum innan og/eða utan lifrar sem getur valdið skorpulifur, lokastigs lifrarbilun og leitt til lifrarígræðslu. Bólgusjúkdómar í meltingarvegi, fyrst og fremst sáraristilbólga, ...
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(2021-04)Drug-induced liver injury (DILI) is a complication of treatment with antituberculosis (TB) drugs, especially in isoniazid (INH)-containing regimens. To investigate genetic risk factors, we performed a genomewide association study (GWAS) involving anti-TB ...
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(2024-03-01)Liver injury associated with the use of a number of different of herbal and dietary supplements are increasingly recognized. It is though often unclear which of the sometimes multiple ingredients are responsible for the liver injury. Several case reports ...
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(2023-08-10)Herb-induced liver injury (HILI) caused by herbal supplements, natural products, and products used in traditional medicine are important for differential diagnoses in patients with acute liver injury without an obvious etiology. The root of Withania ...
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(2023-12)Proton pump inhibitor (PPI) treatment is responsible for substantial gastrin elevation secondary to reduced intragastric acidity. Due to the increasing global prevalence of PPI users, concerns have been raised about the clinical significance of continuous ...
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(2023-03-06)
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(2018-03-05)Inngangur: Faraldrar af völdum lifrarbólgu A veiru (hepatitis A virus, HAV) komu endurtekið upp á Íslandi á fyrrihluta 20. aldar en síðan þá hafa fá tilfelli greinst og engir þekktir faraldrar komið upp síðan 1952. Síðustu íslensku rannsóknir á lifrarbólgu ...
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(2020)Lifrarbólga E er veirusjúkdómur sem berst yfirleitt með menguðu vatni og gengur oftast yfir án sértækra inngripa. Hann er algengur á Indlandi og hefur valdið faröldrum, til að mynda í Asíu, Afríku og Mexíkó, en er sjaldséður á Íslandi. Hér er lýst ...
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(2023-01-01)Background & Aims: No multi-national prospective study of drug-induced liver injury (DILI) has originated in Europe. The design of a prospective European DILI registry, clinical features and short-term outcomes of the cases and controls is reported. ...
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(2022-05-17)Introduction: Idiosyncratic drug-induced liver injury (DILI) is a rare adverse reaction to drugs and other xenobiotics. DILI has different grades of severity and may lead to acute liver failure (ALF), for which there is no effective therapy. N-acetylcysteine ...
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(2021-02)Conducting randomised clinical trials (RCTs) in idiosyncratic drug-induced liver injury (DILI) is challenging. This systematic review aims to summarise the design and findings of RCTs in the prevention and management of idiosyncratic DILI. A systematic ...
Now showing items 1-20 of 27