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  • Styrkarsdottir, Unnur; Thorleifsson, Gudmar; Gudjonsson, Sigurjon A.; Sigurdsson, Asgeir; Center, Jacqueline R.; Lee, Seung Hun; Nguyen, Tuan V.; Kwok, Timothy C.Y.; Lee, Jenny S.W.; Ho, Suzanne C.; Woo, Jean; Leung, Ping-C.; Kim, Beom-Jun; Rafnar, Thorunn; Kiemeney, Lambertus A.; Ingvarsson, Þorvaldur; Koh, Jung-Min; Tang, Nelson L.S.; Eisman, John A.; Christiansen, Claus; Sigurdsson, Gunnar; Thorsteinsdottir, Unnur; Stefansson, Kari (Springer Science and Business Media LLC, 2016-01-06)
    Bone mineral density (BMD) is a measure of osteoporosis and is useful in evaluating the risk of fracture. In a genome-wide association study of BMD among 20,100 Icelanders, with follow-up in 10,091 subjects of European and East-Asian descent, we found ...
  • Norland, Kristján; Sveinbjornsson, Gardar; Thorolfsdottir, Rosa B; Davidsson, Olafur B.; Tragante, Vinicius; Rajamani, Sridharan; Helgadottir, Anna; Grétarsdóttir, Sólveig; van Setten, Jessica; Asselbergs, Folkert W.; Sverrisson, Jon Th.; Stephensen, Sigurdur Sverrir; Óskarsson, Gylfi; Sigurðsson, Emil Lárus; Andersen, Karl; Danielsen, Ragnar; Thorgeirsson, Gudmundur; Thorsteinsdottir, Unnur; Arnar, Davíð O.; sulem, patrick; Holm, Hilma; Gudbjartsson, Daniel; Stefansson, Kari (Springer Science and Business Media LLC, 2019-10-22)
    Features of the QRS complex of the electrocardiogram, reflecting ventricular depolarisation, associate with various physiologic functions and several pathologic conditions. We test 32.5 million variants for association with ten measures of the QRS ...
  • Ívarsdóttir, Erna V.; Benonisdottir, Stefania; Thorleifsson, Gudmar; sulem, patrick; Oddsson, Asmundur; Styrkarsdottir, Unnur; Kristmundsdóttir, Snædís; Arnadottir, Gudny; Thorgeirsson, Gudmundur; Jonsdottir, Ingileif; Zoega, Gunnar M.; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Jónasson, Friðbert; Holm, Hilma; Stefansson, Kari (Springer Science and Business Media LLC, 2019-03-20)
    The corneal endothelium is vital for transparency and proper hydration of the cornea. Here, we conduct a genome-wide association study of corneal endothelial cell density (cells/mm2), coefficient of cell size variation (CV), percentage of hexagonal ...
  • DBDS Genetic Consortium (2022-07-20)
    Detailed knowledge of how diversity in the sequence of the human genome affects phenotypic diversity depends on a comprehensive and reliable characterization of both sequences and phenotypic variation. Over the past decade, insights into this relationship ...
  • Magnus, Fridrik; Warnatz, T.; Palsson, G. K.; Devishvili, A.; Ukleev, V.; Palisaitis, J.; Persson, P. O. Å.; Hjörvarsson, Björgvin (American Physical Society (APS), 2018-05-24)
    Polarized neutron reflectometry is used to determine the sequence of magnetic switching in interlayer exchange coupled Fe/MgO(001) superlattices in an applied magnetic field. For 19.6 Å thick MgO layers we obtain a 90 ∘ periodic magnetic alignment ...
  • Manassi, Mauro; Kristjansson, Arni; Whitney, David (Springer Science and Business Media LLC, 2019-12-01)
    In everyday life, we continuously search for and classify objects in the environment around us. This kind of visual search is extremely important when performed by radiologists in cancer image interpretation and officers in airport security screening. ...
  • Prpic, Valter; Kniestedt, Isabelle; Camilleri, Elizabeth; Gómez-Maureira, Marcello A.; Kristjansson, Arni; Thornton, Ian (Public Library of Science (PLoS), 2019-07-25)
    Traditional search tasks have taught us much about vision and attention. Recently, several groups have begun to use multiple-target search to explore more complex and temporally extended “foraging” behaviour. Many of these new foraging tasks, however, ...
  • Quirk, Sigríður Júlía (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-04)
    The pneumococcus is a major human pathogen that causes morbidity and mortality worldwide. Pneumococci are normally carried asymptomatically in the nasopharynx of healthy pre-school children. Pneumococcal infections can range from acute otitis media ...
  • PSERENADE Team (2021-04-01)
    Pneumococcal conjugate vaccine (PCV) introduction has reduced pneumococcal meningitis incidence. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project described the serotype distribution of remaining pneumococcal meningitis ...
  • Gudmundsdottir, Sigridur Lara; Hrafnkelsson, Hrafn; Sigurdsson, Engilbert; Johannsson, Erlingur (Cambridge University Press (CUP), 2020-03-19)
    Objective: The aim of the study was to assess the potential association between serum 25-hydroxyvitamin D (25(OH)D) and whole-body bone mineral density (BMD) among 16-year-old adolescents and to study the prevalence of 25(OH)D insufficiency, defined ...
  • Emilsson, Valur; Guðmundsson, Elías F.; Aspelund, Thor; Jónsson, Brynjólfur G.; Guðjónsson, Alexander; Launer, Lenore J.; Lamb, John R.; Guðmundsdóttir, Valborg; Jennings, Lori L.; Guðnason, Vilmundur G. (2020-12-16)
    Objective: As severity of outcome in COVID-19 is disproportionately higher among individuals with obesity, smokers, patients with hypertension, kidney disease, chronic pulmonary disease, coronary heart disease (CHD), and/or type 2 diabetes (T2D), serum ...
  • Semba, Richard; Moaddel, Ruin; Cotch, Mary Frances; Jonasson, Fridbert; Eiriksdottir, Gudny; Harris, Tamara B.; Launer, Lenore J.; Sun, Kai; Klein, Ronald; Schaumberg, Debra Ann; Jónsson, Pálmi V.; Gudnason, Vilmundur; Ferrucci, Luigi (Springer Science and Business Media LLC, 2019-01-08)
    Background: Lipids are implicated in the pathogenesis of age-related macular degeneration (AMD). The relationship between systemic lipids and AMD has not been well characterized. The objective was to investigate the relationship between serum lipids ...
  • Pinto, Julian Torres de Miranda; Morales, Manuel; Fedoruk, Mariia; Diemer, Arnaud; Kovaleva, Marina (MDPI AG, 2019-02-07)
    In the pursuit of eco-efficiency, resilience, and self-sufficiency, sustainable cities focus on long-term environmental goals instead of only short-term economic ones. To do so, many of them rely on servitization, the practice of replacing tangible ...
  • Björnsson, Einar S.; Medina-Caliz, Inmaculada; Andrade, Raul J.; Lucena, M. Isabel (2022-05-21)
    Nitrofurantoin, minocycline, methyldopa and infliximab, have been found to induce autoimmune-like hepatitis (DI-AILH). Evidence for other drugs and herbal and dietary supplements (HDS) is unclear. The aims of the study were to establish criteria to ...
  • Xu, Jason; Bjornsson, Einar; Sundaram, Vinay (Oxford University Press (OUP), 2015-12-14)
    Giant cell arteritis (GCA) is a vasculitis of medium and large sized vessels that occurs most often in people >50 years of age with associated symptoms of fever, weight loss, headache and jaw claudication. Polymyalgia rheumatica (PMR), which is ...
  • Kainulainen, Samu; Duce, Brett; Korkalainen, Henri; Oksenberg, Arie; Leino, Akseli; Arnardottir, Erna Sif; Kulkas, Antti; Myllymaa, Sami; Töyräs, Juha; Leppänen, Timo (European Respiratory Society (ERS), 2020-04)
    Current diagnostic parameters estimating obstructive sleep apnoea (OSA) severity have a poor connection to the psychomotor vigilance of OSA patients. Thus, we aimed to investigate how the severity of apnoeas, hypopnoeas and intermittent hypoxaemia is ...
  • Carlsen, Hanne Krage; Valdimarsdóttir, Unnur Anna; Briem, Haraldur; Dominici, Francesca; Finnbjörnsdóttir, Ragnhildur Guðrún; Jóhannsson, Þorsteinn; Aspelund, Thor; Gíslason, Þórarinn; Guðnason, Þórólfur (2021-02-27)
    BACKGROUND: The Holuhraun volcanic eruption September 2014 to February 2015 emitted large amounts of sulfur dioxide (SO 2). The aim of this study was to determine the association between volcanic SO 2 gases on general population respiratory health some ...
  • Oltra, Javier; Habich, Annegret; Schwarz, Christopher G.; Nedelska, Zuzana; Przybelski, Scott A.; Inguanzo, Anna; Diaz-Galvan, Patricia; Lowe, Val J.; Oppedal, Ketil; Gonzalez, Maria C.; Philippi, Nathalie; Blanc, Frederic; Barkhof, Frederik; Lemstra, Afina W.; Hort, Jakub; Padovani, Alessandro; Rektorova, Irena; Bonanni, Laura; Massa, Federico; Kramberger, Milica G.; Taylor, John Paul; Snædal, Jón G; Walker, Zuzana; Antonini, Angelo; Dierks, Thomas; Segura, Barbara; Junque, Carme; Westman, Eric; Boeve, Bradley F.; Aarsland, Dag; Kantarci, Kejal; Ferreira, Daniel (2023-12-22)
    INTRODUCTION: Sex influences neurodegeneration, but it has been poorly investigated in dementia with Lewy bodies (DLB). We investigated sex differences in brain atrophy in DLB using magnetic resonance imaging (MRI). METHODS: We included 436 patients ...
  • Li, Constance H.; Stefansson, Olafur (Springer Science and Business Media LLC, 2020-08-28)
    Sex differences have been observed in multiple facets of cancer epidemiology, treatment and biology, and in most cancers outside the sex organs. Efforts to link these clinical differences to specific molecular features have focused on somatic mutations ...
  • Theorell-Haglöw, Jenny; Ólafsdóttir, Inga Sif; Benediktsdóttir, Bryndís; Gislason, Thorarinn; Lindberg, Eva; Janson, Christer (Dove Medical Press Ltd., 2016-01)