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    Aspirin and other non-steroidal anti-inflammatory drugs and depression, anxiety, and stress-related disorders following a cancer diagnosis: a nationwide register-based cohort study 
    Hu, Kejia; Sjölander, Arvid; Lu, Donghao; Walker, Adam K.; Sloan, Erica K.; Fall, Katja; Valdimarsdottir, Unnur; Hall, Per; Smedby, Karin E.; Fang, Fang (Springer Science and Business Media LLC, 2020-09-09)
    Background: Cancer patients have a highly increased risk of psychiatric disorders following diagnosis, compared with cancer-free individuals. Inflammation is involved in the development of both cancer and psychiatric disorders. The role of non-steroidal ...
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    Aspirin causes endothelium-dependent vasodilation of resistance arteries from non-gravid and gravid rats 
    Helgadottir, Helga; Tropea, Teresa; Gizurarson, Sveinbjorn; Meiri, Hamutal; Mandalà, Maurizio (Elsevier BV, 2019-01)
    Objective:Theobjectiveofthisstudywastounderstandtheeffectofacetylsalicylicacid(aspirin)onresistancearteriesfrommesenteryanduterus.Duringpregnancy,the uterine vasculature undergoes consistent growth to provide sufficient uteroplacental blood flow, a ...
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    Assessing cardiovascular risks from a mid-thigh CT image: A tree-based machine learning approach using radiodensitometric distributions 
    Ricciardi, Carlo; Edmunds, Kyle; Recenti, Marco; Sigurdsson, Sigurdur; Gudnason, Vilmundur; Carraro, Ugo; Gargiulo, Paolo (Springer Science and Business Media LLC, 2020-02-18)
    The nonlinear trimodal regression analysis (NTRA) method based on radiodensitometric CT distributions was recently developed and assessed for the quantification of lower extremity function and nutritional parameters in aging subjects. However, the use ...
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    The assessment and treatment of neurocognition and social cognition in early psychosis 
    Vidarsdottir, Olina (University of Iceland, school of health sciences, faculty of medicine, 2020-09)
    Background: Cognitive impairment is a core feature at all stages of the psychotic illness and significantly predicts functional outcomes. Targeting cognition early is theoretically attractive as a means to reverse the functional impairment before ...
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    Assessment of nutritional biomarkers in pregnant women and associations with gestational diabetes 
    Tryggvadóttir, Ellen Alma (University of Iceland, School of Health Sciences, Faculty of Food Science and Nutrition, 2022-06)
    Background: Gestational diabetes mellitus (GDM) is one of the most common complications diagnosed in pregnancy and is associated with several adverse outcomes for mothers and their offspring. Several factors, both genetic and environmental, are ...
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    Association between maternal gluten intake and type 1 diabetes in offspring: national prospective cohort study in Denmark 
    Antvorskov, Julie C; Halldorsson, Thorhallur; Josefsen, Knud; Svensson, Jannet; Granström, Charlotta; Roep, Bart O; Olesen, Trine H; Hrolfsdottir, Laufey; Buschard, Karsten; Olsen, Sjurdur F. (BMJ, 2018-09-19)
    Objective To examine the association between prenatal gluten exposure and offspring risk of type 1 diabetes in humans. Design National prospective cohort study. Setting National health information registries in Denmark. Participants Pregnant ...
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    Association between prescription of hypnotics/anxiolytics and mortality in multimorbid and non-multimorbid patients: a longitudinal cohort study in primary care 
    Linnet, Kristjan; Sigurdsson, Johann Agust; Tómasdóttir, Margrét Ólafía; Sigurðsson, Emil Lárus; Guðmundsson, Lárus Steinþór (BMJ, 2019-12-05)
    Objectives To assess the risk of mortality in primary care patients, multimorbid (≥2 chronic conditions) or not, prescribed hypnotics/anxiolytics. Design A longitudinal cohort study Setting Primary healthcare in the Reykjavik area. Participants 114 084 ...
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    Association of Dietary Patterns With Testicular Function in Young Danish Men 
    Nassan, Feiby L.; Jensen, Tina K.; Priskorn, Lærke; Halldorsson, Thorhallur; Chavarro, Jorge E.; Jørgensen, Niels (American Medical Association (AMA), 2020-02-21)
    Importance: Diet may play a role in testicular function, but data on how adherence to different diet patterns influences human testicular function are scarce. Objective: To determine whether adherence to specific dietary patterns is associated with ...
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    Association of Dual Decline in Memory and Gait Speed With Risk for Dementia Among Adults Older Than 60 Years 
    Tian, Qu; Resnick, Susan M.; Mielke, Michelle M.; Yaffe, Kristine; Launer, Lenore J.; Jónsson, Pálmi V.; Grande, Giulia; Welmer, Anna-Karin; Laukka, Erika J.; Bandinelli, Stefania; Cherubini, Antonio; Rosano, Caterina; Kritchevsky, Stephen B.; Simonsick, Eleanor M.; Studenski, Stephanie A.; Ferrucci, Luigi (American Medical Association (AMA), 2020-02-21)
    Importance: Dual decline in both memory and gait speed may characterize a group of older individuals at high risk for future dementia. Objective: To assess the risk of dementia in older persons who experience parallel declines in memory and gait speed ...
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    Association of energy and protein intakes with length of stay, readmission and mortality in hospitalised patients with chronic obstructive pulmonary disease 
    Ingadottir, Arora Ros; Beck, Anne M.; Baldwin, Christine; Weekes, C. Elizabeth; Geirsdottir, Olof; Ramel, Alfons; Gislason, Thorarinn; Gunnarsdottir, Ingibjorg (Cambridge University Press (CUP), 2018-03-06)
    Low energy and protein intakes have been associated with an increased risk of malnutrition in outpatients with chronic obstructive pulmonary disease (COPD). We aimed to assess the energy and protein intakes of hospitalised COPD patients according to ...
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    Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis 
    Chen, Hao Yu; Cairns, Benjamin J.; Small, Aeron M.; Burr, Hannah A.; Ambikkumar, Athithan; Martinsson, Andreas; Thériault, Sébastien; Munter, Hans Markus; Steffen, Brian; Zhang, Richard; Levinson, Rebecca T.; Shaffer, Christian M.; Rong, Jian; Sonestedt, Emily; Dufresne, Line; Ljungberg, Johan; Näslund, Ulf; Johansson, Bengt; Ranatunga, Dilrini K.; Whitmer, Rachel A.; Budoff, Matthew J.; Nguyen, Albert; Vasan, Ramachandran S.; Larson, Martin G.; Harris, William S.; Damrauer, Scott M.; Stark, Ken D.; Boekholdt, S. Matthijs; Wareham, Nicholas J.; Pibarot, Philippe; Arsenault, Benoit J.; Mathieu, Patrick; Gudnason, Vilmundur; O’Donnell, Christopher J.; Rotter, Jerome I.; Tsai, Michael Y.; Post, Wendy S.; Clarke, Robert; Söderberg, Stefan; Bossé, Yohan; Wells, Quinn S.; Smith, J. Gustav; Rader, Daniel J.; Lathrop, Mark; Engert, James C.; Thanassoulis, George (American Medical Association (AMA), 2020-06-01)
    Importance: Aortic stenosis (AS) has no approved medical treatment. Identifying etiological pathways for AS could identify pharmacological targets. Objective: To identify novel genetic loci and pathways associated with AS. Design, Setting, and Participants: ...
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    Association of Genetically Predicted Lipid Levels With the Extent of Coronary Atherosclerosis in Icelandic Adults 
    Björnsson, Eyþór; Þorleifsson, Guðmar; Helgadóttir, Anna; Gudnason, Thorarinn; Gudbjartsson, Tomas; Andersen, Karl; Grétarsdóttir, Sólveig; Ólafsson, Ísleifur; Tragante, Vinicius; Ólafsson, Ólafur Hreiðar; Jónsdóttir, Birna; Eyjólfsson, Guðmundur I.; Sigurðardóttir, Ólöf; Thorgeirsson, Gudmundur; Gudbjartsson, Daniel; Thorsteinsdottir, Unnur; Holm, Hilma; Stefansson, Kari (American Medical Association (AMA), 2020-01-01)
    Importance: Genetic studies have evaluated the influence of blood lipid levels on the risk of coronary artery disease (CAD), but less is known about how they are associated with the extent of coronary atherosclerosis. Objective: To estimate the ...
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    Association of glial and neuronal degeneration markers with Alzheimer’s disease cerebrospinal fluid profile and cognitive functions 
    Teitsdóttir, Unnur Diljá; Jónsdóttir, María K.; Lund, Sigrún H.; Darreh-Shori, Taher; Snædal, Jón; Petersen, Pétur H. (Springer Science and Business Media LLC, 2020-08-04)
    Background: Neuroinflammation has gained increasing attention as a potential contributing factor in the onset and progression of Alzheimer's disease (AD). The objective of this study was to examine the association of selected cerebrospinal fluid (CSF) ...
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    Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations 
    Daya, Michelle; Bjarnadóttir, Hrafnhildur (Springer Science and Business Media LLC, 2019-02-20)
    Asthma is a complex disease with striking disparities across racial and ethnic groups. Despite its relatively high burden, representation of individuals of African ancestry in asthma genome-wide association studies (GWAS) has been inadequate, and true ...
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    Associations between intraoperative factors and surgeons’ self-assessed operative satisfaction 
    Erestam, Sofia; Bock, David; Erichsen Andersson, Annette; Bjartell, Anders; Carlsson, Stefan; Stinesen Kollberg, Karin; Sjoberg, Daniel; Steineck, Gunnar; Stranne, Johan; Þorsteinsdóttir, Þórdís; Tyritzis, Stavros; Wallerstedt Lantz, Anna; Wiklund, Peter; Angenete, Eva; Haglind, Eva (Springer Science and Business Media LLC, 2019-03-18)
    Background: Little is known concerning what may infuence surgeon satisfaction with a surgical procedure and its associations with intraoperative factors. The objective was to explore the relationships between surgeons’ self-assessed satisfaction with ...
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    Associations of autozygosity with a broad range of human phenotypes 
    Clark, David W; Okada, Yukinori; Moore, Kristjan H S; Mason, Dan; Pirastu, Nicola; Gandin, Ilaria; Mattsson, Hannele; Barnes, Catriona L K; Lin, Kuang; Zhao, Jing Hua; Deelen, Patrick; Rohde, Rebecca; Schurmann, Claudia; Guo, Xiuqing; Giulianini, Franco; Zhang, Weihua; Medina-Gomez, Carolina; Karlsson, Robert; Bao, Yanchun; Bartz, Traci M; Baumbach, Clemens; Biino, Ginevra; Bixley, Matthew J; Brumat, Marco; Chai, Jin-Fang; Corre, Tanguy; Cousminer, Diana L; Dekker, Annelot M; Eccles, David A; van Eijk, Kristel R; Fuchsberger, Christian; Gao, He; Germain, Marine; Gordon, Scott D; de Haan, Hugoline G; Harris, Sarah E; Hofer, Edith; Huerta-Chagoya, Alicia; Igartua, Catherine; Jansen, Iris E; Jia, Yucheng; Kacprowski, Tim; Karlsson, Torgny; Kleber, Marcus E; Li, Shengchao Alfred; Li-Gao, Ruifang; Mahajan, Anubha; Matsuda, Koichi; Meidtner, Karina; Meng, Weihua; Montasser, May E; van der Most, Peter J; Munz, Matthias; Nutile, Teresa; Palviainen, Teemu; Prasad, Gauri; Prasad, Rashmi B; Priyanka, Tallapragada Divya Sri; Rizzi, Federica; Salvi, Erika; Sapkota, Bishwa R; Shriner, Daniel; Skotte, Line; Smart, Melissa C; Smith, Albert Vernon; van der Spek, Ashley; Spracklen, Cassandra N; Strawbridge, Rona J; Tajuddin, Salman M; Trompet, Stella; Turman, Constance; Verweij, Niek; Viberti, Clara; Wang, Lihua; Warren, Helen R; Wootton, Robyn E; Yanek, Lisa R; Yao, Jie; Yousri, Noha A; Zhao, Wei; Adeyemo, Adebowale A; Afaq, Saima; Aguilar-Salinas, Carlos Alberto; Akiyama, Masato; Albert, Matthew L; Allison, Matthew A; Alver, Maris; Aung, Tin; Azizi, Fereidoun; Bentley, Amy R; Boeing, Heiner; Boerwinkle, Eric; Borja, Judith B; de Borst, Gert J; Bottinger, Erwin P; Broer, Linda; Campbell, Harry; Chanock, Stephen; Chee, Miao-Li; Chen, Guanjie; Chen, Yii-Der I; Chen, Zhengming; Chiu, Yen-Feng; Cocca, Massimiliano; Collins, Francis S; Concas, Maria Pina; Corley, Janie; Cugliari, Giovanni; van Dam, Rob M; Damulina, Anna; Daneshpour, Maryam S; Day, Felix R; Delgado, Graciela E; Dhana, Klodian; Doney, Alexander S F; Dörr, Marcus; Doumatey, Ayo P; Dzimiri, Nduna; Ebenesersdóttir, Sigríður Sunna; Elliott, Joshua; Elliott, Paul; Ewert, Ralf; Felix, Janine F; Fischer, Krista; Freedman, Barry I; Girotto, Giorgia; Goel, Anuj; Gögele, Martin; Goodarzi, Mark O; Graff, Mariaelisa; Granot-Hershkovitz, Einat; Grodstein, Francine; Guarrera, Simonetta; Gudbjartsson, Daniel; Guity, Kamran; Gunnarsson, Bjarni; Guo, Yu; Hagenaars, Saskia P; Haiman, Christopher A; Halevy, Avner; Harris, Tamara B; Hedayati, Mehdi; van Heel, David A; Hirata, Makoto; Höfer, Imo; Hsiung, Chao Agnes; Huang, Jinyan; Hung, Yi-Jen; Ikram, M Arfan; Jagadeesan, Anuradha; Jousilahti, Pekka; Kamatani, Yoichiro; Kanai, Masahiro; Kerrison, Nicola D; Kessler, Thorsten; Khaw, Kay-Tee; Khor, Chiea Chuen; de Kleijn, Dominique P V; Koh, Woon-Puay; Kolcic, Ivana; Kraft, Peter; Krämer, Bernhard K; Kutalik, Zoltán; Kuusisto, Johanna; Langenberg, Claudia; Launer, Lenore J; Lawlor, Deborah A; Lee, I-Te; Lee, Wen-Jane; Lerch, Markus M; Li, Liming; Liu, Jianjun; Loh, Marie; London, Stephanie J; Loomis, Stephanie; Lu, Yingchang; Luan, Jian’an; Mägi, Reedik; Manichaikul, Ani W; Manunta, Paolo; Másson, Gísli; Matoba, Nana; Mei, Xue W; Meisinger, Christa; Meitinger, Thomas; Mezzavilla, Massimo; Milani, Lili; Millwood, Iona Y; Momozawa, Yukihide; Moore, Amy; Morange, Pierre-Emmanuel; Moreno-Macías, Hortensia; Mori, Trevor A; Morrison, Alanna C; Muka, Taulant; Murakami, Yoshinori; Murray, Alison D; de Mutsert, Renée; Mychaleckyj, Josyf C; Nalls, Mike A; Nauck, Matthias; Neville, Matt J; Nolte, Ilja M; Ong, Ken K; Orozco, Lorena; Padmanabhan, Sandosh; Pálsson, Gunnar; Pankow, James S; Pattaro, Cristian; Pattie, Alison; Polasek, Ozren; Poulter, Neil; Pramstaller, Peter P; Quintana-Murci, Lluis; Räikkönen, Katri; Ralhan, Sarju; Rao, Dabeeru C; van Rheenen, Wouter; Rich, Stephen S; Ridker, Paul M; Rietveld, Cornelius A; Robino, Antonietta; van Rooij, Frank J A; Ruggiero, Daniela; Saba, Yasaman; Sabanayagam, Charumathi; Sabater-Lleal, Maria; Sala, Cinzia Felicita; Salomaa, Veikko; Sandow, Kevin; Schmidt, Helena; Scott, Laura J; Scott, William R; Sedaghati-Khayat, Bahareh; Sennblad, Bengt; van Setten, Jessica; Sever, Peter J; Sheu, Wayne H-H; Shi, Yuan; Shrestha, Smeeta; Shukla, Sharvari Rahul; Sigurðsson, Jón K.; Sikka, Timo Tonis; Singh, Jai Rup; Smith, Blair H.; Stančáková, Alena; Stanton, Alice; Starr, John M; Stefánsdóttir, Lilja; Straker, Leon; sulem, patrick; Sveinbjornsson, Gardar; Swertz, Morris A; Taylor, Adele M; Taylor, Kent D; Terzikhan, Natalie; Tham, Yih-Chung; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tillander, Annika; Tracy, Russell P; Tusié-Luna, Teresa; Tzoulaki, Ioanna; Vaccargiu, Simona; Vangipurapu, Jagadish; Veldink, Jan H; Vitart, Veronique; Völker, Uwe; Vuoksimaa, Eero; Wakil, Salma M; Waldenberger, Melanie; Wander, Gurpreet S; Wang, Ya Xing; Wareham, Nicholas J; Wild, Sarah; Yajnik, Chittaranjan S; Yuan, Jian-Min; Zeng, Lingyao; Zhang, Liang; Zhou, Jie; Amin, Najaf; Asselbergs, Folkert W; Bakker, Stephan J L; Becker, Diane M; Lehne, Benjamin; Bennett, David A; van den Berg, Leonard H; Berndt, Sonja I; Bharadwaj, Dwaipayan; Bielak, Lawrence F; Bochud, Murielle; Boehnke, Mike; Bouchard, Claude; Bradfield, Jonathan P; Brody, Jennifer A; Campbell, Archie; Carmi, Shai; Caulfield, Mark J; Cesarini, David; Chambers, John C; Chandak, Giriraj Ratan; Cheng, Ching-Yu; Ciullo, Marina; Cornelis, Marilyn; Cusi, Daniele; Smith, George Davey; Deary, Ian J; Dorajoo, Rajkumar; van Duijn, Cornelia M; Ellinghaus, David; Erdmann, Jeanette; Eriksson, Johan G; Evangelou, Evangelos; Evans, Michele K; Faul, Jessica D; Feenstra, Bjarke; Feitosa, Mary; Foisy, Sylvain; Franke, Andre; Friedlander, Yechiel; Gasparini, Paolo; Gieger, Christian; Gonzalez, Clicerio; Goyette, Philippe; Grant, Struan F A; Griffiths, Lyn R; Groop, Leif; Gudnason, Vilmundur; Gyllensten, Ulf; Hakonarson, Hakon; Hamsten, Anders; van der Harst, Pim; Heng, Chew-Kiat; Hicks, Andrew A; Hochner, Hagit; Huikuri, Heikki; Hunt, Steven C; Jaddoe, Vincent W V; De Jager, Philip L; Johannesson, Magnus; Johansson, Åsa; Jonas, Jost B; Jukema, J. Wouter; Junttila, Juhani; Kaprio, Jaakko; Kardia, Sharon L. R.; Karpe, Fredrik; Kumari, Meena; Laakso, Markku; van der Laan, Sander W; Lahti, Jari; Laudes, Matthias; Lea, Rodney A; Lieb, Wolfgang; Lumley, Thomas; Martin, Nicholas G; März, Winfried; Matullo, Giuseppe; McCarthy, Mark I; Medland, Sarah E; Merriman, Tony R; Metspalu, Andres; Meyer, Brian F; Mohlke, Karen L; Montgomery, Grant W; Mook-Kanamori, Dennis; Munroe, Patricia B; North, Kari E; Nyholt, Dale R; O’connell, Jeffery R; Ober, Carole; Oldehinkel, Albertine J; Palmas, Walter; Palmer, Colin; Pasterkamp, Gerard G; Patin, Etienne; Pennell, Craig E; Perusse, Louis; Peyser, Patricia A; Pirastu, Mario; Polderman, Tinca J. C.; Porteous, David J; Posthuma, Danielle; Psaty, Bruce M; Rioux, John D; Rivadeneira, Fernando; Rotimi, Charles; Rotter, Jerome I; Rudan, Igor; Den Ruijter, Hester M; Sanghera, Dharambir K; Sattar, Naveed; Schmidt, Reinhold; Schulze, Matthias B; Schunkert, Heribert; Scott, Robert A; Shuldiner, Alan R; Sim, Xueling; Small, Neil; Smith, Jennifer A; Sotoodehnia, Nona; Tai, E-Shyong; Teumer, Alexander; Timpson, Nicholas J; Toniolo, Daniela; Tregouet, David-Alexandre; Tuomi, Tiinamaija; Vollenweider, Peter; Wang, Carol A; Weir, David R; Whitfield, John B; Wijmenga, Cisca; Wong, Tien-Yin; Wright, John; Yang, Jingyun; Yu, Lei; Zemel, Babette S; Zonderman, Alan B; Perola, Markus; Magnusson, Patrik K. E.; Uitterlinden, André G; Kooner, Jaspal S; Chasman, Daniel I; Loos, Ruth J. F.; Franceschini, Nora; Franke, Lude; Haley, Chris S; Hayward, Caroline; Walters, Robin G; Perry, John R. B.; Esko, Tōnu; Helgason, Agnar; Stefansson, Kari; Joshi, Peter K; Kubo, Michiaki; Wilson, James F (Springer Science and Business Media LLC, 2019-10-31)
    In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction between close relatives is ...
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    Asthma and COPD overlap (ACO) is related to a high burden of sleep disturbance and respiratory symptoms: Results from the RHINE and Swedish GA2LEN surveys 
    Mindus, Stephanie; Malinovschi, Andrei; Ekerljung, Linda; Forsberg, Bertil; Gislason, Thorarinn; Jõgi, Rain; Franklin, Karl A.; Holm, Mathias; Johannessen, Ane; Middelveld, Roelinde; Schlünssen, Vivi; Svanes, Cecilie; Torén, Kjell; Lindberg, Eva; Janson, Christer (Public Library of Science (PLoS), 2018-04-02)
    Background The term Asthma and COPD Overlap (ACO) describes a condition where asthma and COPD overlap. We aimed to investigate associations between ACO and insomnia and respiratory symptoms, and to investigate the prevalence of ACO and the characteristics ...
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    Atlantic cod (Gadus morhua) trypsin – isoenzyme diversity and antiviral activity 
    Sandholt, Gunnar Birgir (University of Iceland, School of Health Sciences, Faculty of Food Science and Nutrition, 2019-02)
    The aim of the thesis work was to identify and characterise different trypsin isoenzymes from a benzamidine-purified Atlantic cod (Gadus morhua) trypsin isolate. Another aim was to test the ability of cod trypsin to deactivate upper respiratory tract ...
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    Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder 
    Guðmundsson, Ólafur Ó.; Walters, G. Bragi; Ingason, Andrés; Johansson, Stefan; Zayats, Tetyana; Athanasiu, Lavinia; Sonderby, Ida Elken; Gústafsson, Ómar; Nawaz, Muhammad S.; Jónsson, Guðbjörn F.; Jonsson, Lina; Knappskog, Per-Morten; Ingvarsdóttir, Ester; Daviðsdóttir, Katrín; Djurovic, Srdjan; Knudsen, Gun Peggy Strømstad; Askeland, Ragna Bugge; Haraldsdóttir, Gyða S.; Baldursson, Gísli; Magnússon, Páll; Sigurdsson, Engilbert; Gudbjartsson, Daniel; Stefansson, Hreinn; Andreassen, Ole A.; Haavik, Jan; Reichborn-Kjennerud, Ted; Stefansson, Kari (Springer Science and Business Media LLC, 2019-10-17)
    Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable common childhood-onset neurodevelopmental disorder. Some rare copy number variations (CNVs) affect multiple neurodevelopmental disorders such as intellectual disability, autism ...
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    Attractive and repulsive serial biases in visual cognition 
    Rafiei, Mohsen (University of Iceland, School of Health Sciences, Faculty of Psychology, 2021-12-10)
    Our eyes are the primary gates to the visible world around us. Yet, whatever we perceive involves a translation of the patterns of the photons hitting our retinas into mental representations. It could be argued that visual perception is merely an ...