Opin vísindi

Browsing by Subject "Krabbamein"

Browsing by Subject "Krabbamein"

Sort by: Order: Results:

  • Tryggvason, Geir; Briem, Birgir (Læknafélag Íslands / Icelandic Medical Association, 2017-01-05)
    Hnútar í skjaldkirtli eru algengt vandamál og nýgengi þeirra hefur aukist mikið. Kerfisbundin nálgun við uppvinnslu er nauðsynleg til að greining fáist fljótt en ekki síður til að koma í veg fyrir ofgreiningu og ofmeðhöndlun sjúklinga. Það er mikilvægt ...
  • Gudbjartsson, Daniel; Thorsteinsdottir, Unnur (Springer Science and Business Media LLC, 2018-09-13)
    Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of the heritability remains unexplained. We report a new GWAS, a meta-analysis with previous GWAS and a replication series, ...
  • Chen, Ruoqing; Fall, Katja; Czene, Kamila; Kennedy, Beatrice; Valdimarsdottir, Unnur; Fang, Fang (Dove Medical Press Ltd., 2018-05)
    Background: A parental cancer diagnosis is a stressful life event, potentially leading to increased risks of mental and physical problems among children. This study aimed to investigate the associations of parental cancer with IQ, stress resilience, ...
  • Cozzi-Lepri, A; Zangerle, R; Machala, L; Zilmer, K; Ristola, M; Pradier, C; Kirk, O; Sambatakou, H; Fätkenheuer, G; Yust, I; Schmid, P; Gottfredsson, Magnus; Khromova, I; Jilich, D; Flisiak, R; Smidt, J; Rozentale, B; Radoi, R; Losso, MH; Lundgren, JD; Mocroft, A (Wiley, 2017-10-06)
    Objectives There are currently few data on the long‐term risk of cancer and death in individuals taking raltegravir (RAL). The aim of this analysis was to evaluate whether there is evidence for an association. Methods The EuroSIDA cohort was divided ...
  • Islind, Anna Sigridur; Johansson, Victoria; Vallo Hult, Helena; Alsén, Pia; Andreasson, Emma; Angenete, Eva; Gellerstedt, Martin (Springer Science and Business Media LLC, 2020-10-12)
    Purpose The number of colorectal cancer patient survivors is increasing. Information and support during and after treatment are requested by patients, but questions remain on what to provide. The aim of this study was to understand what informational ...
  • de Fine Licht, Sofie; Rugbjerg, Kathrine; Gudmundsdottir, Thorgerdur; Bonnesen, Trine G.; Asdahl, Peter Haubjerg; Holmqvist, Anna Sällfors; Madanat-Harjuoja, Laura; Tryggvadottir, Laufey; Wesenberg, Finn; Hasle, Henrik; Winther, Jeanette F.; Olsen, Jørgen H. (Public Library of Science (PLoS), 2017-05-09)
    Background Survivors of childhood cancer are at increased risk for a wide range of late effects. However, no large population-based studies have included the whole range of somatic diagnoses including subgroup diagnoses and all main types of childhood ...
  • Zimta, Alina-Andreea; Sigurjonsson, Olafur Eysteinn; Gulei, Diana; Tomuleasa, Ciprian (MDPI AG, 2020-08-15)
    Nowadays, advancements in the oncology sector regarding diagnosis methods allow us to specifically detect an increased number of cancer patients, some of them in incipient stages. However, one of the main issues consists of the invasive character of ...
  • Murray, David L.; Puig, Noemi; Kristinsson, Sigurður Yngvi; Usmani, Saad Z.; Dispenzieri, Angela; Bianchi, Giada; Kumar, Shaji; Chng, Wee Joo; Hajek, Roman; Paiva, Bruno; Waage, Anders; Rajkumar, S. Vincent; Durie, Brian (2021-02-01)
    Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect and isotype M-proteins. Increasing ...
  • Anderson, Kimberley (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-04)
    Transcriptional regulatory mechanisms drive the maturation of B cells to plasma cells, with a dramatic transcriptional rewiring taking place during the transition. This rewiring is dependent on a number of factors, including the transcription factor B ...
  • Zhu, Jianwei; Sjölander, Arvid; Fall, Katja; Valdimarsdottir, Unnur; Fang, Fang (Springer Nature, 2018-03-27)
    Background Whether the emotional distress around cancer diagnosis is associated with the long-term outcomes and care utilization is unknown. We aimed to examine the association of mental disorders around cancer diagnosis with the hospital admission ...
  • Schijns, Virgil; Fernández‐Tejada, Alberto; Barjaktarović, Žarko; Bouzalas, Ilias; Brimnes, Jens; Chernysh, Sergey; Gizurarson, Sveinbjorn; Gursel, Ihsan; Jakopin, Žiga; Lawrenz, Maria; Nativi, Cristina; Paul, Stephane; Pedersen, Gabriel Kristian; Rosano, Camillo; Ruiz‐de‐Angulo, Ane; Slütter, Bram; Thakur, Aneesh; Christensen, Dennis; Lavelle, Ed C. (Wiley, 2020-06-28)
    Therapeutic vaccination offers great promise as an intervention for a diversity of infectious and non-infectious conditions. Given that most chronic health conditions are thought to have an immune component, vaccination can at least in principle be ...
  • Shen, Qing; Sjölander, Arvid; Sloan, Erica K.; Walker, Adam K.; Fall, Katja; Valdimarsdóttir, Unnur Anna; Sparén, Pär; Smedby, Karin E.; Fang, Fang (2022-01-17)
    Background: Cancer patients experience increased risk of death from accident and suicide. Cognitive impairment induced by cancer-related inflammation and stress-related psychiatric symptoms may be underlying mechanisms. We therefore studied the association ...
  • Farioli, Andrea; Straif, Kurt; Brandi, Giovanni; Curti, Stefania; Kjaerheim, Kristina; Martinsen, Jan Ivar; Sparen, Pär; Tryggvadottir, Laufey; Weiderpass, Elisabete; Biasco, Guido; Violante, Francesco Saverio; Mattioli, Stefano; Pukkala, Eero (BMJ, 2017-11-13)
    Objectives To assess the association between occupational exposure to asbestos and the risk of cholangiocarcinoma (CC). Methods We conducted a case–control study nested in the Nordic Occupational Cancer (NOCCA) cohort. We studied 1458 intrahepatic ...
  • Pálsdóttir, Edda; Lund, Sigrún Helga; Ásgeirsson, Kristján Skúli (SAGE Publications, 2018-05-14)
    Background and Aims: In Iceland, oncoplastic breast-conservation surgery has been performed since 2008. The aim of this population-based study was to assess and compare the efficacy and patient satisfaction of standard breast-conservation surgery with ...
  • Campbell, Peter J.; Stefansson, Olafur (Springer Science and Business Media LLC, 2020-02-05)
    Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale1,2,3. Here we report the integrative analysis of 2,658 whole-cancer genomes and their ...
  • Gunnell, Anthony S.; Joyce, Sarah; Tomlin, Stephania; Taaffe, Dennis R.; Cormie, Prue; Newton, Robert U.; Joseph, David; Spry, Nigel; Einarsdottir, Kristjana; Galvão, Daniel A. (Frontiers Media SA, 2017-02-14)
    Evidence suggests physical activity improves prognosis following cancer diagnosis; however, evidence regarding prognosis in long-term survivors of cancer is scarce. We assessed physical activity in 1,589 cancer survivors at an average 8.8 years following ...
  • Liedberg, Fredrik; Kollberg, Petter; Allerbo, Marie; Baseckas, Gediminas; Brändstedt, Johan; Gudjónsson, Sigurður; Hagberg, Oskar; Håkansson, Ulf; Jerlström, Tomas; Löfgren, Annica; Patschan, Oliver; Sörenby, Anne; Bläckberg, Mats (2020-11)
    Background: Parastomal hernia (PSH) after urinary diversion with ileal conduit is frequently a clinical problem. Objective: To investigate whether a prophylactic lightweight mesh in the sublay position can reduce the cumulative incidence of PSH after ...
  • Mikropoulos, Christos; Selkirk, Christina G Hutten; Saya, Sibel; Bancroft, Elizabeth; Vertosick, Emily; Dadaev, Tokhir; Brendler, Charles; Page, Elizabeth; Dias, Alexander; Evans, D Gareth; Rothwell, Jeanette; Maehle, Lovise; Axcrona, Karol; Richardson, Kate; Eccles, Diana; Jensen, Thomas; Osther, Palle J; van Asperen, Christi J; Vasen, Hans; Kiemeney, Lambertus A; Ringelberg, Janneke; Cybulski, Cezary; Wokolorczyk, Dominika; Hart, Rachel; Glover, Wayne; Lam, Jimmy; Taylor, Louise; Salinas, Monica; Feliubadaló, Lidia; Oldenburg, Rogier; Cremers, Ruben; Verhaegh, Gerald; van Zelst-Stams, Wendy A; Oosterwijk, Jan C; Cook, Jackie; Rosario, Derek J; Buys, Saundra S; Conner, Tom; Domchek, Susan; Powers, Jacquelyn; Ausems, Margreet GEM; Teixeira, Manuel R; Maia, Sofia; Izatt, Louise; Schmutzler, Rita; Rhiem, Kerstin; Foulkes, William D; Boshari, Talia; Davidson, Rosemarie; Ruijs, Marielle; Helderman-van den Enden, Apollonia TJM; Andrews, Lesley; Walker, Lisa; Snape, Katie; Henderson, Alex; Jobson, Irene; Lindeman, Geoffrey J; Liljegren, Annelie; Harris, Marion; Adank, Muriel A; Kirk, Judy; Taylor, Amy; Susman, Rachel; Chen-Shtoyerman, Rakefet; Pachter, Nicholas; Spigelman, Allan; Side, Lucy; Zgajnar, Janez; Mora, Josefina; Brewer, Carole; Gadea, Neus; Brady, Angela F; Gallagher, David; van Os, Theo; Donaldson, Alan; Stefansdottir, Vigdis; Barwell, Julian; James, Paul A; Murphy, Declan; Friedman, Eitan; Nicolai, Nicola; Greenhalgh, Lynn; Obeid, Elias; Murthy, Vedang; Copakova, Lucia; McGrath, John; Teo, Soo-Hwang; Strom, Sara; Kast, Karin; Leongamornlert, Daniel A; Chamberlain, Anthony; Pope, Jenny; Newlin, Anna C; Aaronson, Neil; Ardern-Jones, Audrey; Bangma, Chris; Castro, Elena; Dearnaley, David; Eyfjörð, Jórunn Erla; Falconer, Alison; Foster, Christopher S; Gronberg, Henrik; Hamdy, Freddie C; Johannsson, Oskar; Khoo, Vincent; Lubinski, Jan; Grindedal, Eli Marie; McKinley, Joanne; Shackleton, Kylie; Mitra, Anita V; Moynihan, Clare; Rennert, Gad; Suri, Mohnish; Tricker, Karen; Moss, Sue; Kote-Jarai, Zsofia; Vickers, Andrew; Lilja, Hans; Helfand, Brian T; Eeles, Rosalind A (Springer Nature, 2018-01)
    Background: Prostate-specific antigen (PSA) and PSA-velocity (PSAV) have been used to identify men at risk of prostate cancer (PrCa). The IMPACT study is evaluating PSA screening in men with a known genetic predisposition to PrCa due to BRCA1/2 ...
  • Hálfdánarson, Óskar (University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-03-08)
    Background and aims: Proton pump inhibitors (PPIs) are commonly prescribed drugs that are used to treat acid-related disorders of the gastrointestinal tract. Over the last decade, PPI use has repeatedly been shown to be increasing worldwide, causing ...
  • Interrante, Mary K.; Segal, Hannah; Peshkin, Beth N.; Valdimarsdottir, Heiddis; Nusbaum, Rachel; Similuk, Morgan; DeMarco, Tiffani; Hooker, Gillian; Graves, Kristi; Isaacs, Claudine; Wood, Marie; McKinnon, Wendy; Garber, Judy; McCormick, Shelley; Heinzmann, Jessica; Kinney, Anita Y.; Schwartz, Marc D. (Oxford University Press (OUP), 2017-09-01)
    Background: Telephone delivery of genetic counseling is an alternative to in-person genetic counseling because it may extend the reach of genetic counseling. Previous reports have established the noninferiority of telephone counseling on short-term ...