Opin vísindi

Fletta eftir efnisorði "Animals"

Fletta eftir efnisorði "Animals"

Röðun: Raða: Niðurstöður:

  • Icon
    High Atlastin 2-2 (ATL2-2) Expression Associates with Worse Prognosis in Estrogen-Receptor-Positive Breast Cancer 
    Reynisdóttir, Inga; Arason, Aðalgeir; Freysteinsdóttir, Edda Sigríður; Kristjánsdóttir, Sigrún Bærings; Hilmarsdóttir, Bylgja; Traustadóttir, Gunnhildur Ásta; Jóhannsson, Óskar Þór; Agnarsson, Bjarni Agnar; Barkardóttir, Rósa Björk (2023-08)
    The disruption of endoplasmic reticulum (ER) homeostasis occurs in many human diseases. Atlastins (ATLs) maintain the branched network of the ER. The dysregulation of ATL2, located at ER network junctions, has been associated with cancer. ATL2 is ...
  • Icon
    Internal relative potency factors based on immunotoxicity for the risk assessment of mixtures of per- and polyfluoroalkyl substances (PFAS) in human biomonitoring 
    Bil, Wieneke; Ehrlich, Veronika; Chen, Guangchao; Vandebriel, Rob; Zeilmaker, Marco; Luijten, Mirjam; Uhl, Maria; Marx-Stoelting, Philip; Halldorsson, Thorhallur Ingi; Bokkers, Bas (2023-01)
    Relative potency factors (RPFs) for per- and polyfluoroalkyl substances (PFAS) have previously been derived based on liver effects in rodents for the purpose of performing mixture risk assessment with primary input from biomonitoring studies. However, ...
  • Icon
    Kvikasilfur í hári barnshafandi kvenna 
    Dufthaksdottir, Edda; Jacobsen, Eva; Eiriksdottir, Asa Valgerdur; Magnúsdóttir, Óla Kallý; Ólafsdóttir, Kristín; Halldórsson, Þórhallur Ingi (2023-03-06)
    Ágrip BAKGRUNNUR Rannsóknir frá Færeyjum hafa sýnt fram á skýr tengsl milli útsetningar móður fyrir kvikasilfri á meðgöngu og taugaþroska fósturs og hafa Matvælaöryggisstofnun Evrópu (EFSA) og Umhverfisstofnun Bandaríkjanna (US-EPA) lagt til mismunandi ...
  • Icon
    MercuNorth–monitoring mercury in pregnant women from the Arctic as a baseline to assess the effectiveness of the Minamata Convention 
    Adlard, Bryan; Lemire, Mélanie; Bonefeld-Jørgensen, Eva C.; Long, Manhai; Ólafsdóttir, Kristín; Odland, Jon O.; Rautio, Arja; Myllynen, Päivi; Sandanger, Torkjel M.; Dudarev, Alexey A.; Bergdahl, Ingvar A.; Wennberg, Maria; Berner, James; Ayotte, Pierre (2021)
    Exposure to mercury (Hg) is a global concern, particularly among Arctic populations that rely on the consumption of marine mammals and fish which are the main route of Hg exposure for Arctic populations.The MercuNorth project was created to establish ...
  • Icon
    Missense variants causing Wiedemann-Steiner syndrome preferentially occur in the KMT2A-CXXC domain and are accurately classified using AlphaFold2 
    Reynisdóttir, Tinna; Anderson, Kimberley Jade; Boukas, Leandros; Björnsson, Hans Tómas (2022-06-21)
    Wiedemann-Steiner syndrome (WDSTS) is a neurodevelopmental disorder caused by de novo variants in KMT2A, which encodes a multi-domain histone methyltransferase. To gain insight into the currently unknown pathogenesis of WDSTS, we examined the spatial ...
  • Icon
    Mouse microphthalmia-associated transcription factor (Mitf) mutations affect the structure of the retinal vasculature 
    Daníelsson, Stefán Broddi; García-Llorca, Andrea; Reynisson, Hallur; Eysteinsson, Thor (2022-03-29)
    Purpose: Mice carrying pathogenic variants in the microphthalmia transcription factor (Mitf) gene show structural and functional changes in the retina and retinal pigment epithelium. The purpose of this study was to assess the vascular changes in Mitf ...
  • Icon
    Neyslutíðni matvæla eða bætiefna og fylgni við styrk langra ómega-3 fitusýra í blóðvökva barnshafandi kvenna 
    Tryggvadóttir, Ellen Alma; Halldórsson, Þórhallur Ingi; Birgisdóttir, Bryndís Eva; Hrólfsdóttir, Laufey; Landberg, Rikard; Hreiðarsdóttir, Ingibjörg Th; Harðardóttir, Hildur; Gunnarsdóttir, Ingibjörg (2022-05-06)
    TILGANGUR Fyrri rannsóknir benda til að hluti barnshafandi kvenna á Íslandi uppfylli ekki ráðlögð viðmið fyrir neyslu langra ómega-3 fitusýra, sem eru taldar mikilvægar fyrir fósturþroska. Markmið rannsóknarinnar var að meta neyslutíðni barnshafandi ...
  • Icon
    Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction 
    Tribble, James R.; Otmani, Amin; Sun, Shanshan; Ellis, Sevannah A.; Cimaglia, Gloria; Vohra, Rupali; Jöe, Melissa; Lardner, Emma; Venkataraman, Abinaya P.; Domínguez-Vicent, Alberto; Kokkali, Eirini; Rho, Seungsoo; Jóhannesson, Gauti; Burgess, Robert W.; Fuerst, Peter G.; Brautaset, Rune; Kolko, Miriam; Morgan, James E.; Crowston, Jonathan G.; Votruba, Marcela; Williams, Pete A. (2021-07)
    Nicotinamide adenine dinucleotide (NAD) is a REDOX cofactor and metabolite essential for neuronal survival. Glaucoma is a common neurodegenerative disease in which neuronal levels of NAD decline. We assess the effects of nicotinamide (a precursor to ...
  • Icon
    Oestrogenic Regulation of Mitochondrial Dynamics 
    Kalkhoran, Siavash Beikoghli; Kararigas, Georgios (2022-02-01)
    Biological sex influences disease development and progression. The steroid hormone 17β-oestradiol (E2), along with its receptors, is expected to play a major role in the manifestation of sex differences. E2 exerts pleiotropic effects in a system-specific ...
  • Icon
    Overestimation of school-based deworming coverage resulting from school-based reporting 
    Sheahan, William; Anderson, Roy; Aruldas, Kumudha; Avokpaho, Euripide; Galagan, Sean; Goodman, Jeanne; Houngbegnon, Parfait; Israel, Gideon John; Janagaraj, Venkateshprabhu; Kaliappan, Saravanakumar Puthupalayam; Means, Arianna Rubin; Morozoff, Chloe; Pearman, Emily; Ramesh, Rohan Michael; Roll, Amy; Schaefer, Alexandra; Simwanza, James; Witek-Mcmanus, Stefan; Ajjampur, Sitara S.R.; Bailey, Robin; Ibikounlé, Moudachirou; Kalua, Khumbo; Luty, Adrian J.F.; Pullan, Rachel; Walson, Judd L.; Ásbjörnsdóttir, Kristjana Hrönn (2023-04-10)
    BACKGROUND: Soil Transmitted Helminths (STH) infect over 1.5 billion people globally and are associated with anemia and stunting, resulting in an annual toll of 1.9 million Disability-Adjusted Life Years (DALYs). School-based deworming (SBD), via mass ...
  • Icon
    Peripheral blood DNA methylation and neuroanatomical responses to HDACi treatment that rescues neurological deficits in a Kabuki syndrome mouse model 
    Goodman, Sarah Jessica; Luperchio, Teresa Romeo; Ellegood, Jacob; Chater-Diehl, Eric; Lerch, Jason P.; Björnsson, Hans Tómas; Weksberg, Rosanna (2023-12)
    Background: Recent findings from studies of mouse models of Mendelian disorders of epigenetic machinery strongly support the potential for postnatal therapies to improve neurobehavioral and cognitive deficits. As several of these therapies move into ...
  • Icon
    PFASs : What can we learn from the European Human Biomonitoring Initiative HBM4EU 
    Uhl, Maria; Schoeters, Greet; Govarts, Eva; Bil, Wieneke; Fletcher, Tony; Haug, Line Småstuen; Hoogenboom, Ron; Gundacker, Claudia; Trier, Xenia; Fernandez, Mariana F.; Calvo, Argelia Castaño; López, Marta Esteban; Coertjens, Dries; Santonen, Tiina; Murínová, Ľubica Palkovičová; Richterová, Denisa; Brouwere, Katleen De; Hauzenberger, Ingrid; Kolossa-Gehring, Marike; Halldórsson, Þórhallur Ingi (2023-05)
    Per- and polyfluoroalkyl substances (PFASs) were one of the priority substance groups selected which have been investigated under the ambitious European Joint programme HBM4EU (2017–2022). In order to answer policy relevant questions concerning exposure ...
  • Icon
    The Predation Game : Does dividing attention affect patterns of human foraging? 
    Thornton, Ian M.; Tagu, Jérôme; Zdravković, Sunčica; Kristjánsson, Árni (2021-05-06)
    Attention is known to play an important role in shaping the behaviour of both human and animal foragers. Here, in three experiments, we built on previous interactive tasks to create an online foraging game for studying divided attention in human ...
  • Icon
    Ritual Animal Killing and Burial Customs in Viking Age Iceland 
    Leifsson, Rúnar (University of Iceland, School of Humanities, Faculty of History and Philosophy, 2018-05)
    In this thesis the ritual killing and burial of animals on grave-fields in Viking Age Iceland is critically re-evaluated, on a site-by-site basis, in order to characterize these customs and place them in a social and historical context. The foundation ...
  • Icon
    Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy 
    Dillard, Pierre; Köksal, Hakan; Maggadóttir, Sólrún Melkorka; Winge-Main, Anna; Pollmann, Sylvie; Menard, Mathilde; Myhre, Marit Renée; Mælandsmo, Gunhild M.; Flørenes, Vivi Ann; Gaudernack, Gustav; Kvalheim, Gunnar; Wälchli, Sébastien; Inderberg, Else Marit (2021-03-03)
    T cell receptor (TCR)-engineered T cell therapy is a promising cancer treatment approach. Human telomerase reverse transcriptase (hTERT) is overexpressed in the majority of tumors and a potential target for adoptive cell therapy. We isolated a novel ...
  • Icon
    Use of acellular intact fish skin grafts in treating acute paediatric wounds during the COVID-19 pandemic : A case series 
    Ciprandi, Guido; Kjartansson, Hilmar; Grussu, Francesca; Baldursson, Baldur Tumi; Frattaroli, Jacopo; Urbani, Urbano; Zama, Mario (2022-10-02)
    OBJECTIVE: More specific strategies are needed to support children requiring skin grafting. Our goal was to identify procedures that reduce operating times, post-operative complications, pain and length of hospital stay. Patient safety, optimal wound ...
  • Icon
    Use of Fish Skin Graft in Management of Combat Injuries Following Military Drone Assaults in Field-Like Hospital Conditions 
    Reda, Fouad; Kjartansson, Hilmar; Jeffery, Steven L A (2023-11-03)
    INTRODUCTION: The 2020 Nagorno-Karabakh war was an armed conflict between Azerbaijan and Armenia over an ethnically and historically significant region. This manuscript is a report on the forward deployment of acellular fish skin graft (FSG) from ...