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Browsing by Subject "Mergæxli"
Now showing items 1-9 of 9
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(Public Library of Science (PLoS), 2018-11-01)The etiology of monoclonal gammopathy of undetermined significance (MGUS), the precursor state of multiple myeloma (MM), is mostly unknown and no studies have been conducted on the effect of diet on MGUS or progression from MGUS to MM. We aimed to ... -
(Springer Science and Business Media LLC, 2018-09-13)Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of the heritability remains unexplained. We report a new GWAS, a meta-analysis with previous GWAS and a replication series, ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2025-06)Introduction and aims: Multiple myeloma (MM) is a hematological malignancy, characterized by the proliferation and accumulation of malignant plasma cells in the bone marrow (BM), leading to overproduction of monoclonal protein (M-protein) and/or free ...
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(University of Iceland, School of Health Science, Faculty of Medicine, 2024-11)Abstract Introduction and aims: Multiple myeloma (MM) is a haematological malignancy caused by abnormal plasma cell proliferation in the bone marrow. All MM cases are preceded by a precursor condition, monoclonal gammopathy of undetermined significance ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-04)Transcriptional regulatory mechanisms drive the maturation of B cells to plasma cells, with a dramatic transcriptional rewiring taking place during the transition. This rewiring is dependent on a number of factors, including the transcription factor B ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2023-10-10)Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic disorder caused by the accumulation of monoclonal immunoglobulin secreting cells in the bone marrow. The main clinical implication of MGUS is that it’s the precursor of multiple ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2019-02)Background and aim: Multiple myeloma is a malignant chronic B-cell disorder characterized by a monoclonal proliferation of plasma cells in the bone marrow. Almost all multiple myeloma cases are preceded by the premalignant state, monoclonal gammopathy ...
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(Ferrata Storti Foundation (Haematologica), 2017-12-07)Epidemiology and outcome of myeloma are mainly reported from large university centers and collaborative groups, and do not represent ‘real-world’ patients. The Swedish Myeloma Registry is a prospective population-based registry documenting characteristics, ...
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(University of Iceland, School of Health Sciences, Faculty of Medicine, 2021-05-21)Inngangur: Með tilkomu áhrifaríkari lyfja í meðhöndlun sjúklinga með mergæxli síðastliðna áratugi hefur lifun þeirra stóraukist. Þessi aukna lifun hefur leitt til aukinnar áherslu rannsakennda á langtíma afleiðingum í formi þróun annarra krabbameina. ...
Now showing items 1-9 of 9