Browsing by Subject "Adverse drug reactions"

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Diabetes mellitus increases risk of adverse drug reactions and death in hospitalised older people : the SENATOR trial

Chinmayee, Anagha; Subbarayan, Selvarani; Myint, Phyo Kyaw; Cherubini, Antonio; Cruz-Jentoft, Alfonso J.; Petrovic, Mirko; Guðmundsson, Aðalsteinn; Byrne, Stephen; O’Mahony, Denis; Soiza, Roy L. (2024-02)

PURPOSE: Adverse drug reactions (ADRs) are a major cause of morbidity and mortality, especially in older people. Older people with diabetes mellitus may be at especially high risk of ADRs but this risk has not been well studied. This study aimed to ...
Genetic association of gemcitabine/carboplatin-induced leukopenia and neutropenia in non-small cell lung cancer patients using whole-exome sequencing

Svedberg, Anna; Björn, Niclas; Sigurgeirsson, Benjamín; Pradhananga, Sailendra; Brandén, Eva; Koyi, Hirsh; Lewensohn, Rolf; De Petris, Luigi; Apellániz-Ruiz, María; Rodríguez-Antona, Cristina; Lundeberg, Joakim; Gréen, Henrik (Elsevier BV, 2020-09)

Objectives: Gemcitabine/carboplatin treatment is known to cause severe adverse drug reactions which can lead to the need for reduction or cessation of chemotherapy. It would be beneficial to identify patients at risk of severe hematological toxicity ...

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