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Fletta eftir höfundi "Þorsteinsdóttir, Margrét"

Fletta eftir höfundi "Þorsteinsdóttir, Margrét"

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    Automated Cancer Diagnostics via Analysis of Optical and Chemical Images by Deep and Shallow Learning 
    Ísberg, Ólöf Gerður; Giunchiglia, Valentina; McKenzie, James S.; Takats, Zoltan; Jónasson, Jón Gunnlaugur; Bodvarsdottir, Sigridur Klara; Þorsteinsdóttir, Margrét; Xiang, Yuchen (2022-05-18)
    Optical microscopy has long been the gold standard to analyse tissue samples for the diagnostics of various diseases, such as cancer. The current diagnostic workflow is time-consuming and labour-intensive, and manual annotation by a qualified pathologist ...
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    The effect of sample age on the metabolic information extracted from formalin-fixed and paraffin embedded tissue samples using desorption electrospray ionization mass spectrometry imaging 
    Ísberg, Ólöf Gerður; Xiang, Yuchen; Böðvarsdóttir, Sigríður Klara; Jónasson, Jón Gunnlaugur; Þorsteinsdóttir, Margrét; Takats, Zoltan (2021-11)
    Background: Metabolites, especially lipids, have been shown to be promising therapeutic targets. In conjugation with genes and proteins they can be used to identify phenotypes of disease and support the development of targeted treatments. The majority ...
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    Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease 
    Helgadottir, Anna; Thorleifsson, Gudmar; Alexandersson, Kristjan F; Tragante, Vinicius; Þorsteinsdóttir, Margrét; Eiriksson, Finnur Freyr; Grétarsdóttir, Sólveig; Björnsson, Eyþór; Magnússon, Ólafur; Sveinbjornsson, Gardar; Jonsdottir, Ingileif; Steinthorsdottir, Valgerdur; Ferkingstad, Egil; Jensson, Brynjar Ö; Stefansson, Hreinn; Olafsson, Isleifur; Christensen, Alex H; Torp-Pedersen, Christian; Køber, Lars; Pedersen, Ole B; Erikstrup, Christian; Sørensen, Erik; Brunak, Søren; Banasik, Karina; Hansen, Thomas F; Nyegaard, Mette; Eyjólfsson, Guðmundur I.; Sigurdardottir, Olof; Þórarinsson, Björn L; Matthíasson, Stefán E.; Steingrimsdottir, Thora; Björnsson, Einar Stefán; Danielsen, Ragnar; Asselbergs, Folkert W.; Arnar, David O; Ullum, Henrik; Bundgaard, Henning; sulem, patrick; Thorsteinsdottir, Unnur; Thorgeirsson, Gudmundur; Holm, Hilma; Gudbjartsson, Daniel; Stefansson, Kari (Oxford University Press (OUP), 2020-07-21)
    Aims: To explore whether variability in dietary cholesterol and phytosterol absorption impacts the risk of coronary artery disease (CAD) using as instruments sequence variants in the ABCG5/8 genes, key regulators of intestinal absorption of dietary ...
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    Genetic variability in the uptake of dietary sterols affects the risk of coronary artery disease 
    Eiríksson, Finnur Freyr; Helgadottir, Anna; Thorleifsson, Gudmar; Alexandersson, Kristjan F.; Tragante, Vinicius; Þorsteinsdóttir, Margrét; Grétarsdóttir, Solveig; Björnsson, Eyþór; Magnússon, Ólafur; Sveinbjornsson, Gardar; Jónsdóttir, Ingileif; Steinthorsdottir, Valgerdur; Ferkingstad, Egil; Jensson, Brynjar Ö; Stefansson, Hreinn; Ólafsson, Ísleifur; Christensen, Alex H; Torp-Pedersen, Christian; Køber, Lars; Pedersen, Ole B; Erikstrup, Christian; Sorensen, Erik; Brunak, Søren; Banasik, Karina; Hansen, Thomas Folkmann; Nyegaard, Mette; Eyjolfssson, Gudmundur I; Sigurdardottir, Olof; Thorarinsson, Bjorn L; Matthiasson, Stefan E.; Steingrimsdottir, Thora; Bjornsson, Einar S; Danielsen, Ragnar; Asselbergs, Folkert W; Arnar, Davíð Ottó; Ullum, Henrik; Bundgaard, Henning; sulem, patrick; Thorsteinsdottir, Unnur; Thorgeirsson, Gudmundur; Holm, Hilma; Gudbjartsson, Daniel F; Stefansson, Kari (2020)
    Aims To explore whether variability in dietary cholesterol and phytosterol absorption impacts the risk of coronary artery disease (CAD) using as instruments sequence variants in the ABCG5/8 genes, key regulators of intestinal absorption of dietary ...
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    Lipidomic study of cell lines reveals differences between breast cancer subtypes 
    Eiríksson, Finnur F.; Nøhr, Martha Kampp; Costa, Margarida; Bodvarsdottir, Sigridur Klara; Ögmundsdóttir, Helga M.; Þorsteinsdóttir, Margrét (Public Library of Science (PLoS), 2020-04-14)
    Breast cancer (BC) is the most prevalent type of cancer in women in western countries. BC mortality has not declined despite early detection by screening, indicating the need for better informed treatment decisions. Therefore, a novel noninvasive ...
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    Lipidomic study of cell lines reveals lipid biomarkers for breast cancer subtypes 
    Eiríksson, Finnur Freyr; Nøhr, Martha Kampp; Costa, Margarida; Bodvarsdottir, Sigridur Klara; Ögmundsdóttir, Helga M; Þorsteinsdóttir, Margrét (2020)
    Breast cancer (BC) is the most prevalent type of cancer in women in western countries. BC mortality has not declined despite early detection by screening, indicating the need for better informed treatment decisions. Therefore, a novel noninvasive ...
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    Metabolic Profiling as a Screening Tool for Cytotoxic Compounds: Identification of 3-Alkyl Pyridine Alkaloids from Sponges Collected at a Shallow Water Hydrothermal Vent Site North of Iceland 
    Einarsdóttir, Eydís; Magnúsdóttir, Manuela; Astarita, Giuseppe; Köck, Matthias; Ögmundsdóttir, Helga M.; Þorsteinsdóttir, Margrét; Rapp, Hans; Omarsdottir, Sesselja; Paglia, Giuseppe (MDPI AG, 2017-02-22)
    Twenty-eight sponge specimens were collected at a shallow water hydrothermal vent site north of Iceland. Extracts were prepared and tested in vitro for cytotoxic activity, and eight of them were shown to be cytotoxic. A mass spectrometry (MS)-based ...
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    Optimization and validation of a UPLC-MS/MS assay for simultaneous quantification of 2,8-dihydroxyadenine, adenine, allopurinol, oxypurinol and febuxostat in human plasma 
    Thorsteinsdottir, Unnur A; Runólfsdóttir, Hrafnhildur L.; Eiríksson, Finnur Freyr; Ágústsd., Inger María Schweitz; Eðvarðsson, Viðar Örn; Pálsson, Runólfur; Þorsteinsdóttir, Margrét (2024-03-01)
    Adenine phosphoribosyltransferase (APRT) deficiency is a rare , hereditary disorder characterized by renal excretion of 2,8-dihydroxyadenine (DHA), leading to kidney stone formation and chronic kidney disease (CKD). Treatment with a xanthine oxidoreductase ...