Browsing by Author "Ísaksson, Helgi Jóhannes"

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NAC blocks Cystatin C amyloid complex aggregation in a cell system and in skin of HCCAA patients

March, Michael E.; Gutierrez-Uzquiza, Alvaro; Snorradottir, Asbjorg Osk; Matsuoka, Leticia S.; Balvis, Noelia Fonseca; Gestsson, Thorgeir; Nguyen, Kenny; Sleiman, Patrick M.A.; Kao, Charlly; Ísaksson, Helgi Jóhannes; Bragason, Birkir Thor; Ólafsson, Elías; Palsdottir, Astridur; Hakonarson, Hakon (2021-03-23)

Hereditary cystatin C amyloid angiopathy is a dominantly inherited disease caused by a leucine to glutamine variant of human cystatin C (hCC). L68Q-hCC forms amyloid deposits in brain arteries associated with micro-infarcts, leading ultimately to ...
Surgical lung biopsy for suspected interstitial lung disease with video-assisted thoracoscopic surgery is safe, providing exact histological and disease specific diagnosis for tailoring treatment

Thrainsson, Leifur; Halldorsson, Arnljotur Bjorn; Ingason, Arnar Bragi; Ísaksson, Helgi Jóhannes; Guðmundsson, Gunnar; Guðbjartsson, Tómas (2024-01)

Background: Surgical lung biopsy (SLB) is required for diagnosis in patients with suspected interstitial lung disease (ILD) if other less invasive diagnostic methods are non-conclusive. We evaluated the outcome of SLB by using centralized databases in ...

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